STRINGSTRING
wdr48 wdr48 ercc1 ercc1 fancl fancl ube2t ube2t uba52 uba52 rpa2 rpa2 kxd1 kxd1 nutf2 nutf2 fancd2 fancd2 atrip atrip rpa3 rpa3 slx4 slx4 LOC102314666 LOC102314666 eme2 eme2 rpa1 rpa1 eme1 eme1 ubb ubb meiob meiob usp1 usp1 faap24 faap24 ercc4 ercc4 atr atr fanci fanci ENSHBUP00000010143 ENSHBUP00000010143 SLX1 SLX1 mus81 mus81 fancf fancf ENSHBUP00000008606 ENSHBUP00000008606 proser1 proser1 RPA1 RPA1 fancm fancm dclre1a dclre1a fancc fancc rps27a rps27a cenpx cenpx fan1 fan1 LOC102303702 LOC102303702 LOC102308588 LOC102308588 dclre1b dclre1b fancb fancb FAAP100 FAAP100 fanca fanca
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
wdr48WD repeat domain 48b. (685 aa)
ercc1Excision repair cross-complementation group 1. (352 aa)
fanclFA complementation group L. (371 aa)
ube2tUbiquitin-conjugating enzyme E2T (putative). (192 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
rpa2Replication protein A2. (293 aa)
kxd1KxDL motif containing 1. (184 aa)
nutf2Nuclear transport factor 2. (127 aa)
fancd2FA complementation group D2. (1335 aa)
atripUncharacterized protein. (789 aa)
rpa3Replication protein A3. (122 aa)
slx4SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1628 aa)
LOC102314666Ubiquitin-like domain-containing protein. (131 aa)
eme2ERCC4 domain-containing protein. (276 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
eme1Essential meiotic structure-specific endonuclease 1. (526 aa)
ubbUbiquitin-like domain-containing protein. (54 aa)
meiobMethionine sulfoxide reductase B1b. (464 aa)
usp1Ubiquitin carboxyl-terminal hydrolase. (828 aa)
faap24FA core complex associated protein 24. (216 aa)
ercc4Excision repair cross-complementation group 4. (899 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3139 aa)
fanciFA complementation group I. (1285 aa)
ENSHBUP00000010143Polymerase (DNA directed) nu. (1094 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (256 aa)
mus81MUS81 structure-specific endonuclease subunit. (650 aa)
fancfFA complementation group F. (343 aa)
ENSHBUP00000008606FA complementation group G. (622 aa)
proser1Proline and serine rich 1. (777 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa)
fancmUncharacterized protein. (2114 aa)
dclre1aDNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (931 aa)
fanccFA complementation group C. (558 aa)
rps27aRibosomal protein S27a. (156 aa)
cenpxCentromere protein X. (89 aa)
fan1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1106 aa)
LOC102303702NTF2 domain-containing protein. (130 aa)
LOC102308588Centromere protein S. (123 aa)
dclre1bDNA cross-link repair 1B. (586 aa)
fancbFA complementation group B. (777 aa)
FAAP100FA core complex associated protein 100. (866 aa)
fancaFanconi_A_N domain-containing protein. (1213 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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