STRINGSTRING
LOC102293146 LOC102293146 ercc2 ercc2 gtf2h4 gtf2h4 LOC102303915 LOC102303915 ENSHBUP00000001568 ENSHBUP00000001568 polr2i polr2i nelfcd nelfcd ell ell elob elob nelfb nelfb tceanc2 tceanc2 polr2h polr2h gtf2h5 gtf2h5 phf3 phf3 gtf2f1 gtf2f1 polr2j polr2j ENSHBUP00000007553 ENSHBUP00000007553 ccnh ccnh ccnq ccnq ssrp1 ssrp1 POLR2E POLR2E polr2g polr2g nelfa nelfa cdk7 cdk7 polr2l polr2l cdk13 cdk13 ccnk ccnk LOC102298451 LOC102298451 supt5h supt5h polr2d polr2d POLR2B POLR2B ccnt2 ccnt2 ENSHBUP00000016698 ENSHBUP00000016698 polr2a polr2a gtf2h1 gtf2h1 ENSHBUP00000018586 ENSHBUP00000018586 polr2f polr2f LOC102296285 LOC102296285 mnat1 mnat1 nelfe nelfe polr2k polr2k ercc3 ercc3 gtf2f2 gtf2f2 LOC102297138 LOC102297138 gtf2h3 gtf2h3 ccnt1 ccnt1 tcea1 tcea1 TCEANC TCEANC cdk9 cdk9 LOC102307883 LOC102307883 eloa eloa ENSHBUP00000032420 ENSHBUP00000032420 LOC102292669 LOC102292669 supt4h1 supt4h1 polr2c polr2c supt16h supt16h
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102293146Cyclin-dependent kinase 12. (1352 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
LOC102303915General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (252 aa)
ENSHBUP00000001568Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (116 aa)
polr2iPolymerase (RNA) II (DNA directed) polypeptide I. (135 aa)
nelfcdNegative elongation factor complex member C/D. (579 aa)
ellElongation factor RNA polymerase II. (676 aa)
elobUbiquitin-like domain-containing protein. (119 aa)
nelfbNegative elongation factor complex member B. (583 aa)
tceanc2Uncharacterized protein. (260 aa)
polr2hDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
phf3PHD finger protein 3. (1704 aa)
gtf2f1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (552 aa)
polr2jPolymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
ENSHBUP00000007553Elongin B. (103 aa)
ccnhCyclin H; Belongs to the cyclin family. (335 aa)
ccnqCyclin Q; Belongs to the cyclin family. (254 aa)
ssrp1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (704 aa)
POLR2ERNA polymerase II subunit E. (138 aa)
polr2gPolymerase (RNA) II (DNA directed) polypeptide G-like. (181 aa)
nelfaNegative elongation factor complex member A. (547 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
polr2lPolymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
cdk13Cyclin-dependent kinase 13. (1417 aa)
ccnkCyclin K; Belongs to the cyclin family. (539 aa)
LOC102298451Si:dkey-12j5.1. (461 aa)
supt5hTranscription elongation factor SPT5. (1082 aa)
polr2dRPOL4c domain-containing protein. (509 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1088 aa)
ccnt2Cyclin T2. (731 aa)
ENSHBUP00000016698FCP1_C domain-containing protein. (180 aa)
polr2aDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1906 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (550 aa)
ENSHBUP00000018586TFIIS N-terminal domain-containing protein. (406 aa)
polr2fPolymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
LOC102296285Transcription elongation factor A (SII), 2. (331 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
nelfeNegative elongation factor complex member E. (393 aa)
polr2kPolymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
ercc3Excision repair cross-complementation group 3. (783 aa)
gtf2f2General transcription factor IIF, polypeptide 2a. (248 aa)
LOC102297138Elongin A, like. (630 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (305 aa)
ccnt1Cyclin T1; Belongs to the cyclin family. (702 aa)
tcea1Transcription elongation factor A (SII), 1. (311 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (345 aa)
cdk9Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. (393 aa)
LOC102307883Cyclin T2b; Belongs to the cyclin family. (565 aa)
eloaElongin A. (559 aa)
ENSHBUP00000032420FCP1 homology domain-containing protein. (278 aa)
LOC102292669General transcription factor IIH subunit. (392 aa)
supt4h1SPT4 homolog, DSIF elongation factor subunit. (94 aa)
polr2cPolymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
supt16hSPT16 homolog, facilitates chromatin remodeling subunit. (1030 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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