56 items (Haplochromis burtoni) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	LOC102293146	Cyclin-dependent kinase 12. (1352 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (461 aa)
	LOC102303915	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (252 aa)
	ENSHBUP00000001568	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (116 aa)
	polr2i	Polymerase (RNA) II (DNA directed) polypeptide I. (135 aa)
	nelfcd	Negative elongation factor complex member C/D. (579 aa)
	ell	Elongation factor RNA polymerase II. (676 aa)
	elob	Ubiquitin-like domain-containing protein. (119 aa)
	nelfb	Negative elongation factor complex member B. (583 aa)
	tceanc2	Uncharacterized protein. (260 aa)
	polr2h	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	gtf2h5	General transcription factor IIH, polypeptide 5. (71 aa)
	phf3	PHD finger protein 3. (1704 aa)
	gtf2f1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (552 aa)
	polr2j	Polymerase (RNA) II (DNA directed) polypeptide J. (117 aa)
	ENSHBUP00000007553	Elongin B. (103 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (335 aa)
	ccnq	Cyclin Q; Belongs to the cyclin family. (254 aa)
	ssrp1	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (704 aa)
	POLR2E	RNA polymerase II subunit E. (138 aa)
	polr2g	Polymerase (RNA) II (DNA directed) polypeptide G-like. (181 aa)
	nelfa	Negative elongation factor complex member A. (547 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
	polr2l	Polymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
	cdk13	Cyclin-dependent kinase 13. (1417 aa)
	ccnk	Cyclin K; Belongs to the cyclin family. (539 aa)
	LOC102298451	Si:dkey-12j5.1. (461 aa)
	supt5h	Transcription elongation factor SPT5. (1082 aa)
	polr2d	RPOL4c domain-containing protein. (509 aa)
	POLR2B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1088 aa)
	ccnt2	Cyclin T2. (731 aa)
	ENSHBUP00000016698	FCP1_C domain-containing protein. (180 aa)
	polr2a	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1906 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (550 aa)
	ENSHBUP00000018586	TFIIS N-terminal domain-containing protein. (406 aa)
	polr2f	Polymerase (RNA) II (DNA directed) polypeptide F. (127 aa)
	LOC102296285	Transcription elongation factor A (SII), 2. (331 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	nelfe	Negative elongation factor complex member E. (393 aa)
	polr2k	Polymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
	ercc3	Excision repair cross-complementation group 3. (783 aa)
	gtf2f2	General transcription factor IIF, polypeptide 2a. (248 aa)
	LOC102297138	Elongin A, like. (630 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (305 aa)
	ccnt1	Cyclin T1; Belongs to the cyclin family. (702 aa)
	tcea1	Transcription elongation factor A (SII), 1. (311 aa)
	TCEANC	Transcription elongation factor A N-terminal and central domain containing. (345 aa)
	cdk9	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. (393 aa)
	LOC102307883	Cyclin T2b; Belongs to the cyclin family. (565 aa)
	eloa	Elongin A. (559 aa)
	ENSHBUP00000032420	FCP1 homology domain-containing protein. (278 aa)
	LOC102292669	General transcription factor IIH subunit. (392 aa)
	supt4h1	SPT4 homolog, DSIF elongation factor subunit. (94 aa)
	polr2c	Polymerase (RNA) II (DNA directed) polypeptide C. (275 aa)
	supt16h	SPT16 homolog, facilitates chromatin remodeling subunit. (1030 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHBUP00000001568	ENSHBUP00000007553	ENSHBUP00000001568	ENSHBUP00000007553	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	Elongin B.	0.636
ENSHBUP00000001568	ENSHBUP00000016698	ENSHBUP00000001568	ENSHBUP00000016698	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	FCP1_C domain-containing protein.	0.785
ENSHBUP00000001568	ENSHBUP00000018586	ENSHBUP00000001568	ENSHBUP00000018586	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	TFIIS N-terminal domain-containing protein.	0.939
ENSHBUP00000001568	ENSHBUP00000032420	ENSHBUP00000001568	ENSHBUP00000032420	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	FCP1 homology domain-containing protein.	0.785
ENSHBUP00000001568	LOC102292669	ENSHBUP00000001568	ENSHBUP00000034401	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	General transcription factor IIH subunit.	0.725
ENSHBUP00000001568	LOC102293146	ENSHBUP00000001568	ENSHBUP00000000578	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	Cyclin-dependent kinase 12.	0.813
ENSHBUP00000001568	LOC102296285	ENSHBUP00000001568	ENSHBUP00000020190	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	Transcription elongation factor A (SII), 2.	0.939
ENSHBUP00000001568	LOC102297138	ENSHBUP00000001568	ENSHBUP00000024956	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	Elongin A, like.	0.638
ENSHBUP00000001568	LOC102303915	ENSHBUP00000001568	ENSHBUP00000001526	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.734
ENSHBUP00000001568	LOC102307883	ENSHBUP00000001568	ENSHBUP00000030346	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	Cyclin T2b; Belongs to the cyclin family.	0.770
ENSHBUP00000001568	POLR2B	ENSHBUP00000001568	ENSHBUP00000015581	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.984
ENSHBUP00000001568	POLR2E	ENSHBUP00000001568	ENSHBUP00000009323	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	RNA polymerase II subunit E.	0.982
ENSHBUP00000001568	TCEANC	ENSHBUP00000001568	ENSHBUP00000028659	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	Transcription elongation factor A N-terminal and central domain containing.	0.858
ENSHBUP00000001568	ccnh	ENSHBUP00000001568	ENSHBUP00000008328	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	Cyclin H; Belongs to the cyclin family.	0.696
ENSHBUP00000001568	ccnk	ENSHBUP00000001568	ENSHBUP00000013923	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	Cyclin K; Belongs to the cyclin family.	0.849
ENSHBUP00000001568	ccnq	ENSHBUP00000001568	ENSHBUP00000008541	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	Cyclin Q; Belongs to the cyclin family.	0.762
ENSHBUP00000001568	ccnt1	ENSHBUP00000001568	ENSHBUP00000026243	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	Cyclin T1; Belongs to the cyclin family.	0.770
ENSHBUP00000001568	ccnt2	ENSHBUP00000001568	ENSHBUP00000015886	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	Cyclin T2.	0.770
ENSHBUP00000001568	cdk13	ENSHBUP00000001568	ENSHBUP00000012533	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	Cyclin-dependent kinase 13.	0.813
ENSHBUP00000001568	cdk7	ENSHBUP00000001568	ENSHBUP00000010765	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily.	0.753