STRINGSTRING
LOC102305036 LOC102305036 taf6 taf6 supt16h supt16h PRKAB2 PRKAB2 rad17 rad17 ENSHBUP00000033633 ENSHBUP00000033633 cdca7l cdca7l ENSHBUP00000033354 ENSHBUP00000033354 ccna2 ccna2 recql4 recql4 LOC102309580 LOC102309580 mre11 mre11 tbp tbp rad1 rad1 dna2 dna2 rpa1 rpa1 hipk2 hipk2 prkaa2 prkaa2 LOC102314666 LOC102314666 chek1 chek1 nuak1 nuak1 rbbp8 rbbp8 rpa3 rpa3 ENSHBUP00000030027 ENSHBUP00000030027 exo1 exo1 atrip atrip LOC102301927 LOC102301927 taf2 taf2 rad9a rad9a prkab1 prkab1 kxd1 kxd1 prkaa1 prkaa1 rpa2 rpa2 uba52 uba52 taf11 taf11 LOC102303734 LOC102303734 LOC102291667 LOC102291667 ENSHBUP00000024920 ENSHBUP00000024920 mdm4 mdm4 cdk5r1 cdk5r1 LOC102308989 LOC102308989 nbn nbn LOC102291467 LOC102291467 dyrk2 dyrk2 tp53rk tp53rk hus1 hus1 rad50 rad50 mapkapk5 mapkapk5 rfc4 rfc4 LOC102296334 LOC102296334 LOC102310380 LOC102310380 rad9b rad9b ENSHBUP00000021576 ENSHBUP00000021576 LOC102299633 LOC102299633 ankrd11 ankrd11 kat5 kat5 LOC102294305 LOC102294305 stk11 stk11 ubb ubb noc2l noc2l LOC102302272 LOC102302272 taf13 taf13 meiob meiob tpx2 tpx2 chek2 chek2 exd2 exd2 cdca7 cdca7 cdk5r2 cdk5r2 tp53inp1 tp53inp1 ENSHBUP00000016295 ENSHBUP00000016295 ENSHBUP00000016017 ENSHBUP00000016017 dyrk4 dyrk4 top3a top3a LOC102303299 LOC102303299 hipk3 hipk3 pin1 pin1 blm blm taf7l taf7l topbp1 topbp1 LOC102289212 LOC102289212 atr atr ENSHBUP00000012655 ENSHBUP00000012655 rfc2 rfc2 tbpl1 tbpl1 TAF4B TAF4B TAF4 TAF4 ENSHBUP00000010635 ENSHBUP00000010635 LOC102299316 LOC102299316 LOC102309545 LOC102309545 LOC102293093 LOC102293093 rhno1 rhno1 LOC102303805 LOC102303805 ssrp1 ssrp1 rfc5 rfc5 ENSHBUP00000009143 ENSHBUP00000009143 ENSHBUP00000009123 ENSHBUP00000009123 slf1 slf1 rmi1 rmi1 LOC102304830 LOC102304830 csnk2a2 csnk2a2 LOC102297562 LOC102297562 ENSHBUP00000007967 ENSHBUP00000007967 RPA1 RPA1 aurka aurka ankrd12 ankrd12 ENSHBUP00000006825 ENSHBUP00000006825 cdk5 cdk5 prkag1 prkag1 prkag3 prkag3 LOC102289231 LOC102289231 tdrd3 tdrd3 LOC102310609 LOC102310609 LOC102303516 LOC102303516 taf5l taf5l ccna1 ccna1 rfc3 rfc3 ENSHBUP00000005062 ENSHBUP00000005062 ENSHBUP00000005048 ENSHBUP00000005048 dyrk3 dyrk3 taf3 taf3 tp53inp2 tp53inp2 tbpl2 tbpl2 LOC102292229 LOC102292229 LOC102293834 LOC102293834 LOC102294513 LOC102294513 cdk2 cdk2 brca1 brca1 LOC102305216 LOC102305216 mdm2 mdm2 LOC102306348 LOC102306348 rps27a rps27a LOC102311348 LOC102311348 rmi2 rmi2 LOC102308859 LOC102308859 LOC102310033 LOC102310033
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102305036Si:ch211-160o17.4. (1137 aa)
taf6TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (638 aa)
supt16hSPT16 homolog, facilitates chromatin remodeling subunit. (1030 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (310 aa)
rad17RAD17 checkpoint clamp loader component. (692 aa)
ENSHBUP00000033633Uncharacterized protein. (363 aa)
cdca7lCell division cycle associated 7b. (402 aa)
ENSHBUP00000033354WD_REPEATS_REGION domain-containing protein. (78 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (434 aa)
recql4RecQ helicase-like 4. (1577 aa)
LOC102309580Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (350 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (695 aa)
tbpTATA box binding protein. (307 aa)
rad1RAD1 homolog (S. pombe). (309 aa)
dna2DNA replication helicase/nuclease 2. (1401 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
hipk2Homeodomain interacting protein kinase 2. (1244 aa)
prkaa2Non-specific serine/threonine protein kinase. (557 aa)
LOC102314666Ubiquitin-like domain-containing protein. (131 aa)
chek1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (460 aa)
nuak1NUAK family, SNF1-like kinase, 1b. (656 aa)
rbbp8Uncharacterized protein. (673 aa)
rpa3Replication protein A3. (122 aa)
ENSHBUP00000030027Protein kinase domain-containing protein. (265 aa)
exo1Exonuclease 1. (737 aa)
atripUncharacterized protein. (789 aa)
LOC102301927TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (247 aa)
taf2TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (1213 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (389 aa)
prkab1Protein kinase, AMP-activated, beta 1 non-catalytic subunit, a. (269 aa)
kxd1KxDL motif containing 1. (184 aa)
prkaa1Non-specific serine/threonine protein kinase. (571 aa)
rpa2Replication protein A2. (293 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
taf11TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (204 aa)
LOC102303734Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (344 aa)
LOC102291667Aurora kinase B; Belongs to the protein kinase superfamily. (305 aa)
ENSHBUP00000024920Protein kinase domain-containing protein. (274 aa)
mdm4MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (495 aa)
cdk5r1Cyclin-dependent kinase 5 activator. (317 aa)
LOC102308989ANK_REP_REGION domain-containing protein. (698 aa)
nbnNibrin. (779 aa)
LOC102291467Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (414 aa)
dyrk2Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2. (592 aa)
tp53rkTP53 regulating kinase. (236 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (285 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
mapkapk5MAPK activated protein kinase 5. (471 aa)
rfc4Replication factor C (activator 1) 4. (357 aa)
LOC102296334Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa)
LOC102310380Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
rad9bRAD9 checkpoint clamp component B. (390 aa)
ENSHBUP00000021576Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (419 aa)
LOC102299633Mitogen-activated protein kinase. (361 aa)
ankrd11Ankyrin repeat domain 11. (2842 aa)
kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (555 aa)
LOC102294305Mitogen-activated protein kinase. (361 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (436 aa)
ubbUbiquitin-like domain-containing protein. (54 aa)
noc2lNOC2-like nucleolar associated transcriptional repressor. (748 aa)
LOC102302272TAFH domain-containing protein. (1094 aa)
taf13TATA-box binding protein associated factor 13. (124 aa)
meiobMethionine sulfoxide reductase B1b. (464 aa)
tpx2TPX2 microtubule nucleation factor. (701 aa)
chek2Checkpoint kinase 2. (521 aa)
exd2Exonuclease 3'-5' domain containing 2. (635 aa)
cdca7Cell division cycle associated 7a. (401 aa)
cdk5r2Cyclin-dependent kinase 5, regulatory subunit 2b (p39). (295 aa)
tp53inp1Tumor protein p53 inducible nuclear protein 1. (296 aa)
ENSHBUP00000016295TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (163 aa)
ENSHBUP00000016017Protein kinase domain-containing protein. (109 aa)
dyrk4Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4. (650 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1037 aa)
LOC102303299Cyclin-dependent kinase 5 activator. (349 aa)
hipk3Homeodomain interacting protein kinase 3b. (1342 aa)
pin1Peptidyl-prolyl cis-trans isomerase. (156 aa)
blmBLM RecQ like helicase. (1405 aa)
taf7lTAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (362 aa)
topbp1DNA topoisomerase II binding protein 1. (1538 aa)
LOC102289212Protein kinase domain-containing protein. (242 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (3139 aa)
ENSHBUP00000012655Protein kinase domain-containing protein. (360 aa)
rfc2Replication factor C (activator 1) 2. (356 aa)
tbpl1TBP-like 1. (187 aa)
TAF4BTATA-box binding protein associated factor 4b. (683 aa)
TAF4TATA-box binding protein associated factor 4. (992 aa)
ENSHBUP00000010635Uncharacterized protein. (203 aa)
LOC102299316TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor. (854 aa)
LOC102309545Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b. (268 aa)
LOC102293093Uncharacterized protein. (294 aa)
rhno1Si:ch73-352p4.5. (295 aa)
LOC102303805Mitogen-activated protein kinase. (361 aa)
ssrp1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (704 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
ENSHBUP00000009143AAA_23 domain-containing protein. (92 aa)
ENSHBUP00000009123Uncharacterized protein. (264 aa)
slf1SMC5-SMC6 complex localization factor 1. (885 aa)
rmi1RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (679 aa)
LOC102304830Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (186 aa)
csnk2a2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (384 aa)
LOC102297562Cyclin-dependent kinase 5 activator. (335 aa)
ENSHBUP00000007967Uncharacterized protein. (215 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa)
aurkaAurora kinase A; Belongs to the protein kinase superfamily. (433 aa)
ankrd12Ankyrin repeat domain 12. (1951 aa)
ENSHBUP00000006825Protein kinase domain-containing protein. (146 aa)
cdk5Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
prkag1Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (326 aa)
prkag3Protein kinase, AMP-activated, gamma 3a non-catalytic subunit. (310 aa)
LOC102289231Si:dkey-219c3.2. (944 aa)
tdrd3Tudor domain containing 3. (780 aa)
LOC102310609Homeodomain interacting protein kinase 1a. (1109 aa)
LOC102303516Uncharacterized protein. (279 aa)
taf5lTAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (600 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (398 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
ENSHBUP00000005062Uncharacterized protein. (143 aa)
ENSHBUP00000005048TAN domain-containing protein. (177 aa)
dyrk3Dual specificity tyrosine phosphorylation regulated kinase 3. (604 aa)
taf3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto. (935 aa)
tp53inp2Uncharacterized protein. (320 aa)
tbpl2TATA box binding protein like 2. (320 aa)
LOC102292229Zgc:86598; Belongs to the protein kinase superfamily. (392 aa)
LOC102293834Mitogen-activated protein kinase. (364 aa)
LOC102294513Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
brca1Uncharacterized protein. (1388 aa)
LOC102305216Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (438 aa)
mdm2MDM2 proto-oncogene. (522 aa)
LOC102306348Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily. (393 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC102311348Transcription initiation factor TFIID subunit. (1830 aa)
rmi2RecQ mediated genome instability 2. (146 aa)
LOC102308859NUAK family, SNF1-like kinase, 2. (625 aa)
LOC102310033Protein kinase domain-containing protein. (1369 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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