40 items (Haplochromis burtoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cdk2	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
	LOC102299999	Uncharacterized protein. (477 aa)
	mdm2	MDM2 proto-oncogene. (522 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC102290684	Serine/threonine-protein phosphatase. (309 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	LOC102295930	Ubiquitin carboxyl-terminal hydrolase. (414 aa)
	SGK1	Non-specific serine/threonine protein kinase. (626 aa)
	ENSHBUP00000029663	Uncharacterized protein. (151 aa)
	rictor	RPTOR independent companion of MTOR, complex 2 a. (1704 aa)
	LOC102314666	Ubiquitin-like domain-containing protein. (131 aa)
	LOC102301386	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	ccna2	Cyclin A2; Belongs to the cyclin family. (434 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2516 aa)
	LOC102300128	Ring finger protein 34b. (419 aa)
	LOC102297192	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
	rffl	Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase. (346 aa)
	usp7	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1112 aa)
	ENSHBUP00000009952	PH domain-containing protein. (146 aa)
	LOC102314329	Ubiquitin carboxyl-terminal hydrolase. (574 aa)
	mapkap1	MAPK associated protein 1. (529 aa)
	LOC102301101	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
	chek2	Checkpoint kinase 2. (521 aa)
	mlst8	MTOR associated protein, LST8 homolog (S. cerevisiae). (326 aa)
	rnf34	Ring finger protein 34a. (378 aa)
	cdk1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (307 aa)
	LOC102296098	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	phf20	PHD finger protein 20, a. (1003 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	ubb	Ubiquitin-like domain-containing protein. (54 aa)
	ccna1	Cyclin A1; Belongs to the cyclin family. (398 aa)
	txndc11	Thioredoxin domain containing 11. (858 aa)
	ENSHBUP00000005062	Uncharacterized protein. (143 aa)
	LOC102296334	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa)
	pdpk1	3-phosphoinositide dependent protein kinase 1b. (565 aa)
	mdm4	MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (495 aa)
	ENSHBUP00000005048	TAN domain-containing protein. (177 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHBUP00000005048	ENSHBUP00000005062	ENSHBUP00000005048	ENSHBUP00000005062	TAN domain-containing protein.	Uncharacterized protein.	0.923
ENSHBUP00000005048	ENSHBUP00000009952	ENSHBUP00000005048	ENSHBUP00000009952	TAN domain-containing protein.	PH domain-containing protein.	0.510
ENSHBUP00000005048	LOC102296098	ENSHBUP00000005048	ENSHBUP00000011927	TAN domain-containing protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.510
ENSHBUP00000005048	LOC102296334	ENSHBUP00000005048	ENSHBUP00000022213	TAN domain-containing protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.989
ENSHBUP00000005048	LOC102297192	ENSHBUP00000005048	ENSHBUP00000034621	TAN domain-containing protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.510
ENSHBUP00000005048	LOC102301101	ENSHBUP00000005048	ENSHBUP00000005571	TAN domain-containing protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.510
ENSHBUP00000005048	LOC102314666	ENSHBUP00000005048	ENSHBUP00000031002	TAN domain-containing protein.	Ubiquitin-like domain-containing protein.	0.677
ENSHBUP00000005048	akt1	ENSHBUP00000005048	ENSHBUP00000014267	TAN domain-containing protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.510
ENSHBUP00000005048	ccna1	ENSHBUP00000005048	ENSHBUP00000005298	TAN domain-containing protein.	Cyclin A1; Belongs to the cyclin family.	0.705
ENSHBUP00000005048	ccna2	ENSHBUP00000005048	ENSHBUP00000032902	TAN domain-containing protein.	Cyclin A2; Belongs to the cyclin family.	0.705
ENSHBUP00000005048	cdk1	ENSHBUP00000005048	ENSHBUP00000012669	TAN domain-containing protein.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.691
ENSHBUP00000005048	cdk2	ENSHBUP00000005048	ENSHBUP00000003403	TAN domain-containing protein.	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.	0.682
ENSHBUP00000005048	chek2	ENSHBUP00000005048	ENSHBUP00000017690	TAN domain-containing protein.	Checkpoint kinase 2.	0.988
ENSHBUP00000005048	mdm2	ENSHBUP00000005048	ENSHBUP00000002884	TAN domain-containing protein.	MDM2 proto-oncogene.	0.890
ENSHBUP00000005048	mdm4	ENSHBUP00000005048	ENSHBUP00000024857	TAN domain-containing protein.	MDM4 regulator of p53; Belongs to the MDM2/MDM4 family.	0.843
ENSHBUP00000005048	mtor	ENSHBUP00000005048	ENSHBUP00000032917	TAN domain-containing protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.729
ENSHBUP00000005048	rps27a	ENSHBUP00000005048	ENSHBUP00000002167	TAN domain-containing protein.	Ribosomal protein S27a.	0.648
ENSHBUP00000005062	ENSHBUP00000005048	ENSHBUP00000005062	ENSHBUP00000005048	Uncharacterized protein.	TAN domain-containing protein.	0.923
ENSHBUP00000005062	ENSHBUP00000009952	ENSHBUP00000005062	ENSHBUP00000009952	Uncharacterized protein.	PH domain-containing protein.	0.510
ENSHBUP00000005062	LOC102296098	ENSHBUP00000005062	ENSHBUP00000011927	Uncharacterized protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.510