STRINGSTRING
LOC102302540 LOC102302540 psma3 psma3 rps27a rps27a LOC102305606 LOC102305606 ENSHBUP00000002798 ENSHBUP00000002798 psmd6 psmd6 LOC102302267 LOC102302267 cdk2 cdk2 LOC102297571 LOC102297571 LOC102313461 LOC102313461 LOC102299742 LOC102299742 LOC102300113 LOC102300113 H3-3B H3-3B LOC102305723 LOC102305723 ENSHBUP00000004241 ENSHBUP00000004241 ENSHBUP00000004642 ENSHBUP00000004642 LOC102296354 LOC102296354 cdc6 cdc6 LOC102289461 LOC102289461 LOC102312912 LOC102312912 LOC102312282 LOC102312282 prim2 prim2 psmd9 psmd9 psmf1 psmf1 ube2c ube2c pole2 pole2 psma4 psma4 orc4 orc4 RPA1 RPA1 anapc7 anapc7 mcm9 mcm9 ENSHBUP00000007917 ENSHBUP00000007917 PSMD11 PSMD11 LOC102297270 LOC102297270 pole4 pole4 bicra bicra ENSHBUP00000008801 ENSHBUP00000008801 orc5 orc5 LOC102300494 LOC102300494 LOC102300798 LOC102300798 LOC102299877 LOC102299877 anapc10 anapc10 LOC102290216 LOC102290216 LOC102298961 LOC102298961 cdc16 cdc16 mcm3 mcm3 mcm6 mcm6 pola2 pola2 ENSHBUP00000010708 ENSHBUP00000010708 LOC102314202 LOC102314202 LOC102298027 LOC102298027 ube2s ube2s cdc45 cdc45 fam89a fam89a LOC102292505 LOC102292505 cdc27 cdc27 psmd12 psmd12 ENSHBUP00000014118 ENSHBUP00000014118 psma6 psma6 kpnb1 kpnb1 kpna1 kpna1 psmc2 psmc2 psma1 psma1 psmc3 psmc3 psmb1 psmb1 LOC102295861 LOC102295861 anapc16 anapc16 meiob meiob LOC102307742 LOC102307742 LOC102295674 LOC102295674 ubb ubb cdc23 cdc23 FZR1 FZR1 orc3 orc3 ENSHBUP00000021119 ENSHBUP00000021119 LOC102309100 LOC102309100 LOC102308796 LOC102308796 LOC102306295 LOC102306295 psmc6 psmc6 psmb3 psmb3 psmb2 psmb2 anapc11 anapc11 gmnn gmnn psmd10 psmd10 LOC102289538 LOC102289538 ENSHBUP00000023288 ENSHBUP00000023288 ENSHBUP00000023290 ENSHBUP00000023290 LOC102313157 LOC102313157 psmd14 psmd14 psmc4 psmc4 ENSHBUP00000024446 ENSHBUP00000024446 psme3 psme3 psmd1 psmd1 anapc1 anapc1 psma5 psma5 mcm7 mcm7 cdc7 cdc7 mcm4 mcm4 psmd5 psmd5 pole pole LOC102293513 LOC102293513 bicral bicral uba52 uba52 rpa2 rpa2 ENSHBUP00000026636 ENSHBUP00000026636 kxd1 kxd1 psmd8 psmd8 psmd7 psmd7 ENSHBUP00000027230 ENSHBUP00000027230 LOC102301120 LOC102301120 kpna5 kpna5 psma2 psma2 tm7sf3 tm7sf3 prim1 prim1 anapc5 anapc5 psmc1 psmc1 psme2 psme2 anapc4 anapc4 mcm2 mcm2 rpa3 rpa3 anapc15 anapc15 ENSHBUP00000030614 ENSHBUP00000030614 LOC102314666 LOC102314666 psmb4 psmb4 psmd2 psmd2 mcm10 mcm10 mcm8 mcm8 cdt1 cdt1 rpa1 rpa1 LOC102300965 LOC102300965 cdc26 cdc26 psmd13 psmd13 anapc2 anapc2 psme1 psme1 orc1 orc1 mcm5 mcm5 pola1 pola1 orc2 orc2 psmc5 psmc5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102302540Importin subunit alpha; Belongs to the importin alpha family. (577 aa)
psma3Proteasome subunit alpha type. (255 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC102305606Proteasome subunit beta. (281 aa)
ENSHBUP00000002798Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (389 aa)
LOC102302267Proteasome 26S subunit, non-ATPase 4b. (375 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
LOC102297571Histone H2A; Belongs to the histone H2A family. (179 aa)
LOC102313461Proteasome subunit beta. (304 aa)
LOC102299742Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102300113WD_REPEATS_REGION domain-containing protein. (489 aa)
H3-3BH3 histone, family 3B. (136 aa)
LOC102305723Proteasome 26S subunit, non-ATPase 11b. (422 aa)
ENSHBUP00000004241Polymerase (DNA directed), epsilon 3 (p17 subunit). (147 aa)
ENSHBUP00000004642Uncharacterized protein. (257 aa)
LOC102296354Proteasome subunit beta. (286 aa)
cdc6Cell division cycle 6 homolog (S. cerevisiae). (429 aa)
LOC102289461Proteasome subunit beta. (278 aa)
LOC102312912UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
LOC102312282Ubiquitin-conjugating enzyme E2E 2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (513 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (212 aa)
psmf1Proteasome inhibitor subunit 1. (277 aa)
ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (199 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (532 aa)
psma4Proteasome subunit alpha type. (261 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (498 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa)
anapc7Anaphase promoting complex subunit 7. (565 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1169 aa)
ENSHBUP00000007917Histone H2A; Belongs to the histone H2A family. (151 aa)
PSMD11PCI domain-containing protein. (422 aa)
LOC102297270SCY domain-containing protein. (125 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa)
bicraBRD4 interacting chromatin remodeling complex associated protein. (1775 aa)
ENSHBUP00000008801Histone H2A; Belongs to the histone H2A family. (134 aa)
orc5Origin recognition complex, subunit 5. (450 aa)
LOC102300494Proteasome subunit beta. (216 aa)
LOC102300798Proteasome subunit beta 12. (226 aa)
LOC102299877Proteasome subunit beta. (275 aa)
anapc10Anaphase promoting complex subunit 10. (143 aa)
LOC102290216Histone H2A; Belongs to the histone H2A family. (138 aa)
LOC102298961Histone H2A; Belongs to the histone H2A family. (129 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (619 aa)
mcm3DNA helicase; Belongs to the MCM family. (811 aa)
mcm6DNA helicase; Belongs to the MCM family. (828 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (602 aa)
ENSHBUP00000010708Rpn3_C domain-containing protein. (104 aa)
LOC102314202Proteasome subunit alpha type. (246 aa)
LOC102298027DBF4 zinc finger. (433 aa)
ube2sUbiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (233 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (568 aa)
fam89aFamily with sequence similarity 89 member A. (180 aa)
LOC102292505Fizzy/cell division cycle 20 related 1b. (532 aa)
cdc27Cell division cycle 27. (802 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (456 aa)
ENSHBUP00000014118Histone H2A; Belongs to the histone H2A family. (139 aa)
psma6Proteasome subunit alpha type. (246 aa)
kpnb1Karyopherin (importin) beta 1. (876 aa)
kpna1Importin subunit alpha; Belongs to the importin alpha family. (494 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (442 aa)
psma1Proteasome subunit alpha type. (263 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (476 aa)
psmb1Proteasome subunit beta. (237 aa)
LOC102295861Histone H3.3. (136 aa)
anapc16Anaphase promoting complex subunit 16. (108 aa)
meiobMethionine sulfoxide reductase B1b. (464 aa)
LOC102307742Histone domain-containing protein. (222 aa)
LOC102295674Proteasome 26S subunit, non-ATPase 4a. (377 aa)
ubbUbiquitin-like domain-containing protein. (54 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (575 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (496 aa)
orc3Origin recognition complex, subunit 3. (720 aa)
ENSHBUP00000021119Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC102309100Histone H3.3. (136 aa)
LOC102308796Histone H3.3. (136 aa)
LOC102306295Proteasome subunit alpha type. (246 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (330 aa)
psmb3Proteasome subunit beta. (205 aa)
psmb2Proteasome subunit beta. (229 aa)
anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (94 aa)
gmnnGeminin DNA replication inhibitor. (227 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (226 aa)
LOC102289538Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ENSHBUP00000023288Histone H2B; Belongs to the histone H2B family. (128 aa)
ENSHBUP00000023290Uncharacterized protein. (125 aa)
LOC102313157Proteasome subunit beta. (275 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (310 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa)
ENSHBUP00000024446Histone H2B; Belongs to the histone H2B family. (135 aa)
psme3Proteasome activator subunit 3. (256 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (957 aa)
anapc1Anaphase promoting complex subunit 1. (1982 aa)
psma5Proteasome subunit alpha type. (241 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (740 aa)
cdc7Cell division cycle 7 homolog (S. cerevisiae). (611 aa)
mcm4DNA helicase; Belongs to the MCM family. (860 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (504 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2016 aa)
LOC102293513Histone H2B; Belongs to the histone H2B family. (116 aa)
bicralBRD4 interacting chromatin remodeling complex associated protein like. (797 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
rpa2Replication protein A2. (293 aa)
ENSHBUP00000026636Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (104 aa)
kxd1KxDL motif containing 1. (184 aa)
psmd8Proteasome 26S subunit, non-ATPase 8. (265 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (332 aa)
ENSHBUP00000027230Histone H3; Belongs to the histone H3 family. (95 aa)
LOC102301120Proteasome subunit beta. (275 aa)
kpna5Importin subunit alpha; Belongs to the importin alpha family. (536 aa)
psma2Proteasome endopeptidase complex. (164 aa)
tm7sf3Transmembrane 7 superfamily member 3. (565 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (426 aa)
anapc5Anaphase promoting complex subunit 5. (771 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
psme2Proteasome activator subunit 2. (245 aa)
anapc4Anaphase promoting complex subunit 4. (756 aa)
mcm2DNA helicase; Belongs to the MCM family. (886 aa)
rpa3Replication protein A3. (122 aa)
anapc15Anaphase promoting complex subunit 15. (122 aa)
ENSHBUP00000030614Uncharacterized protein. (95 aa)
LOC102314666Ubiquitin-like domain-containing protein. (131 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (906 aa)
mcm10Minichromosome maintenance 10 replication initiation factor. (867 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (844 aa)
cdt1Chromatin licensing and DNA replication factor 1. (607 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
LOC102300965Ubiquitin-conjugating enzyme E2E 1; Belongs to the ubiquitin-conjugating enzyme family. (218 aa)
cdc26Cell division cycle 26 homolog. (87 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (378 aa)
anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (646 aa)
psme1Proteasome activator subunit 1. (230 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (898 aa)
mcm5DNA helicase; Belongs to the MCM family. (767 aa)
pola1DNA polymerase. (1482 aa)
orc2Origin recognition complex, subunit 2. (604 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (448 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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