STRINGSTRING
psme2 psme2 znf385c znf385c psma3 psma3 LOC102304617 LOC102304617 ENSHBUP00000002040 ENSHBUP00000002040 rps27a rps27a LOC102305606 LOC102305606 psmd6 psmd6 mdm2 mdm2 LOC102306852 LOC102306852 LOC102302267 LOC102302267 cdk2 cdk2 LOC102313461 LOC102313461 LOC102305723 LOC102305723 ENSHBUP00000004642 ENSHBUP00000004642 cop1 cop1 ENSHBUP00000005048 ENSHBUP00000005048 ENSHBUP00000005062 ENSHBUP00000005062 LOC102296354 LOC102296354 ccna1 ccna1 LOC102289461 LOC102289461 psmd9 psmd9 psmf1 psmf1 ENSHBUP00000006730 ENSHBUP00000006730 psma4 psma4 psme4 psme4 LOC102300494 LOC102300494 LOC102300798 LOC102300798 LOC102299877 LOC102299877 ENSHBUP00000010708 ENSHBUP00000010708 LOC102314202 LOC102314202 phf20 phf20 LOC102300709 LOC102300709 cdkn1b cdkn1b psmd12 psmd12 psma6 psma6 psmc2 psmc2 psma1 psma1 psmc3 psmc3 psmb1 psmb1 LOC102313340 LOC102313340 chek2 chek2 LOC102307929 LOC102307929 LOC102295674 LOC102295674 ubb ubb LOC102306295 LOC102306295 psmc6 psmc6 psmb3 psmb3 psmb2 psmb2 LOC102296334 LOC102296334 psmd10 psmd10 ENSHBUP00000022635 ENSHBUP00000022635 LOC102296801 LOC102296801 LOC102294796 LOC102294796 LOC102304719 LOC102304719 psmd14 psmd14 psma8 psma8 psmc4 psmc4 psme3 psme3 psmd1 psmd1 mdm4 mdm4 psma5 psma5 psmd5 psmd5 uba52 uba52 kxd1 kxd1 psmd8 psmd8 psmd7 psmd7 ENSHBUP00000027335 ENSHBUP00000027335 psma2 psma2 psmc1 psmc1 ENSHBUP00000029663 ENSHBUP00000029663 LOC102298978 LOC102298978 ENSHBUP00000030614 ENSHBUP00000030614 LOC102314666 LOC102314666 psmb4 psmb4 psmd13 psmd13 ccna2 ccna2 psme1 psme1 ccne1 ccne1 LOC102307191 LOC102307191 psmc5 psmc5 PSMD11 PSMD11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
psme2Proteasome activator subunit 2. (245 aa)
znf385cZinc finger protein 385C. (589 aa)
psma3Proteasome subunit alpha type. (255 aa)
LOC102304617Cyclin-dependent kinase inhibitor 1A. (169 aa)
ENSHBUP00000002040Proteasome subunit beta. (299 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC102305606Proteasome subunit beta. (281 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (389 aa)
mdm2MDM2 proto-oncogene. (522 aa)
LOC102306852Uncharacterized protein. (178 aa)
LOC102302267Proteasome 26S subunit, non-ATPase 4b. (375 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
LOC102313461Proteasome subunit beta. (304 aa)
LOC102305723Proteasome 26S subunit, non-ATPase 11b. (422 aa)
ENSHBUP00000004642Uncharacterized protein. (257 aa)
cop1COP1 E3 ubiquitin ligase. (715 aa)
ENSHBUP00000005048TAN domain-containing protein. (177 aa)
ENSHBUP00000005062Uncharacterized protein. (143 aa)
LOC102296354Proteasome subunit beta. (286 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (398 aa)
LOC102289461Proteasome subunit beta. (278 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (212 aa)
psmf1Proteasome inhibitor subunit 1. (277 aa)
ENSHBUP00000006730Uncharacterized protein. (181 aa)
psma4Proteasome subunit alpha type. (261 aa)
psme4Proteasome activator subunit 4a. (1811 aa)
LOC102300494Proteasome subunit beta. (216 aa)
LOC102300798Proteasome subunit beta 12. (226 aa)
LOC102299877Proteasome subunit beta. (275 aa)
ENSHBUP00000010708Rpn3_C domain-containing protein. (104 aa)
LOC102314202Proteasome subunit alpha type. (246 aa)
phf20PHD finger protein 20, a. (1003 aa)
LOC102300709Cyclin-dependent kinase inhibitor 1Cb. (208 aa)
cdkn1bCyclin-dependent kinase inhibitor 1Bb. (184 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (456 aa)
psma6Proteasome subunit alpha type. (246 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (442 aa)
psma1Proteasome subunit alpha type. (263 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (476 aa)
psmb1Proteasome subunit beta. (237 aa)
LOC102313340Cyclin E2; Belongs to the cyclin family. (391 aa)
chek2Checkpoint kinase 2. (521 aa)
LOC102307929Proteasome activator subunit 4b. (1804 aa)
LOC102295674Proteasome 26S subunit, non-ATPase 4a. (377 aa)
ubbUbiquitin-like domain-containing protein. (54 aa)
LOC102306295Proteasome subunit alpha type. (246 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (330 aa)
psmb3Proteasome subunit beta. (205 aa)
psmb2Proteasome subunit beta. (229 aa)
LOC102296334Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ENSHBUP00000022635Cyclin-dependent kinase inhibitor 1A. (163 aa)
LOC102296801Uncharacterized protein. (543 aa)
LOC102294796Zinc finger protein 385A. (445 aa)
LOC102304719Uncharacterized protein. (181 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (310 aa)
psma8Proteasome subunit alpha type. (296 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa)
psme3Proteasome activator subunit 3. (256 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (957 aa)
mdm4MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (495 aa)
psma5Proteasome subunit alpha type. (241 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (504 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
kxd1KxDL motif containing 1. (184 aa)
psmd8Proteasome 26S subunit, non-ATPase 8. (265 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (332 aa)
ENSHBUP00000027335C2H2-type domain-containing protein. (339 aa)
psma2Proteasome endopeptidase complex. (164 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
ENSHBUP00000029663Uncharacterized protein. (151 aa)
LOC102298978Uncharacterized protein. (427 aa)
ENSHBUP00000030614Uncharacterized protein. (95 aa)
LOC102314666Ubiquitin-like domain-containing protein. (131 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (378 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (434 aa)
psme1Proteasome activator subunit 1. (230 aa)
ccne1Cyclin E1; Belongs to the cyclin family. (462 aa)
LOC102307191Proteasome subunit beta11b. (362 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (448 aa)
PSMD11PCI domain-containing protein. (422 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.