STRINGSTRING
yap1 yap1 kat2a kat2a LOC102313759 LOC102313759 psma3 psma3 LOC102314283 LOC102314283 rps27a rps27a LOC102305606 LOC102305606 SRC SRC psmd6 psmd6 mdm2 mdm2 maml1 maml1 LOC102302267 LOC102302267 LOC102313461 LOC102313461 LOC102305723 LOC102305723 LOC102294096 LOC102294096 ENSHBUP00000004642 ENSHBUP00000004642 LOC102294501 LOC102294501 LOC102296354 LOC102296354 LOC102296331 LOC102296331 LOC102296758 LOC102296758 LOC102289249 LOC102289249 LOC102312355 LOC102312355 LOC102289461 LOC102289461 psmd9 psmd9 psmf1 psmf1 psma4 psma4 PSMD11 PSMD11 ENSHBUP00000008944 ENSHBUP00000008944 LOC102292622 LOC102292622 LOC102300494 LOC102300494 LOC102300798 LOC102300798 LOC102299877 LOC102299877 ENSHBUP00000010363 ENSHBUP00000010363 notch1 notch1 ENSHBUP00000010708 ENSHBUP00000010708 LOC102314202 LOC102314202 zfhx3 zfhx3 TEAD4 TEAD4 fndc3b fndc3b LOC106632273 LOC106632273 psmd12 psmd12 ENSHBUP00000013863 ENSHBUP00000013863 ENSHBUP00000013881 ENSHBUP00000013881 tcf7l2 tcf7l2 psma6 psma6 psmc2 psmc2 psma1 psma1 ep300 ep300 psmc3 psmc3 psmb1 psmb1 LOC102305578 LOC102305578 rbpj rbpj LOC102295674 LOC102295674 hes4 hes4 LOC102309260 LOC102309260 ubb ubb LOC102304566 LOC102304566 LOC102306757 LOC102306757 LOC102313654 LOC102313654 LOC102306295 LOC102306295 psmc6 psmc6 psmb3 psmb3 maml2 maml2 psmb2 psmb2 fndc3a fndc3a maml3 maml3 cbfb cbfb LOC102296334 LOC102296334 psmd10 psmd10 LOC102298276 LOC102298276 psmd14 psmd14 psmc4 psmc4 psme3 psme3 hes1 hes1 psmd1 psmd1 psma5 psma5 LOC102293257 LOC102293257 psmd5 psmd5 uba52 uba52 psmd8 psmd8 psmd7 psmd7 psma2 psma2 tcf7l1 tcf7l1 psmc1 psmc1 ccnd1 ccnd1 snw1 snw1 psme2 psme2 smurf1 smurf1 TEAD1 TEAD1 SMURF2 SMURF2 ENSHBUP00000030562 ENSHBUP00000030562 ENSHBUP00000030614 ENSHBUP00000030614 lef1 lef1 LOC102306633 LOC102306633 LOC102314666 LOC102314666 psmb4 psmb4 psmd2 psmd2 psmd13 psmd13 psme1 psme1 runx3 runx3 tcf7 tcf7 rbpjl rbpjl ctnnb1 ctnnb1 zfhx4 zfhx4 psmc5 psmc5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yap1Yes-associated protein 1. (436 aa)
kat2aHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (798 aa)
LOC102313759TEA domain family member 1a. (428 aa)
psma3Proteasome subunit alpha type. (255 aa)
LOC102314283Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC102305606Proteasome subunit beta. (281 aa)
SRCTyrosine-protein kinase. (550 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (389 aa)
mdm2MDM2 proto-oncogene. (522 aa)
maml1Mastermind-like transcriptional coactivator 1. (972 aa)
LOC102302267Proteasome 26S subunit, non-ATPase 4b. (375 aa)
LOC102313461Proteasome subunit beta. (304 aa)
LOC102305723Proteasome 26S subunit, non-ATPase 11b. (422 aa)
LOC102294096Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (294 aa)
ENSHBUP00000004642Uncharacterized protein. (257 aa)
LOC102294501TEA domain transcription factor 3. (426 aa)
LOC102296354Proteasome subunit beta. (286 aa)
LOC102296331Uncharacterized protein. (247 aa)
LOC102296758Tyrosine-protein kinase. (590 aa)
LOC102289249Notch receptor 1a. (2455 aa)
LOC102312355Mothers against decapentaplegic homolog. (606 aa)
LOC102289461Proteasome subunit beta. (278 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (212 aa)
psmf1Proteasome inhibitor subunit 1. (277 aa)
psma4Proteasome subunit alpha type. (261 aa)
PSMD11PCI domain-containing protein. (422 aa)
ENSHBUP00000008944TEA domain family member 3 b. (346 aa)
LOC102292622Mothers against decapentaplegic homolog. (510 aa)
LOC102300494Proteasome subunit beta. (216 aa)
LOC102300798Proteasome subunit beta 12. (226 aa)
LOC102299877Proteasome subunit beta. (275 aa)
ENSHBUP00000010363HMG box domain-containing protein. (172 aa)
notch1Notch receptor 1b. (2411 aa)
ENSHBUP00000010708Rpn3_C domain-containing protein. (104 aa)
LOC102314202Proteasome subunit alpha type. (246 aa)
zfhx3Zinc finger homeobox 3. (3883 aa)
TEAD4TEA domain transcription factor 4. (422 aa)
fndc3bFibronectin type III domain containing 3Ba. (1204 aa)
LOC106632273Recombination signal binding protein for immunoglobulin kappa J region a. (496 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (456 aa)
ENSHBUP00000013863Homeobox domain-containing protein. (295 aa)
ENSHBUP00000013881HMG box domain-containing protein. (303 aa)
tcf7l2Transcription factor 7 like 2. (631 aa)
psma6Proteasome subunit alpha type. (246 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (442 aa)
psma1Proteasome subunit alpha type. (263 aa)
ep300E1A binding protein p300 b. (2764 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (476 aa)
psmb1Proteasome subunit beta. (237 aa)
LOC102305578HMG box domain-containing protein. (580 aa)
rbpjRecombination signal binding protein for immunoglobulin kappa J region. (490 aa)
LOC102295674Proteasome 26S subunit, non-ATPase 4a. (377 aa)
hes4Hairy-related 9. (285 aa)
LOC102309260Mothers against decapentaplegic homolog. (503 aa)
ubbUbiquitin-like domain-containing protein. (54 aa)
LOC102304566E3 ubiquitin-protein ligase. (842 aa)
LOC102306757E1A binding protein p300 a. (2600 aa)
LOC102313654Hairy-related 8.2. (190 aa)
LOC102306295Proteasome subunit alpha type. (246 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (330 aa)
psmb3Proteasome subunit beta. (205 aa)
maml2MamL-1 domain-containing protein. (895 aa)
psmb2Proteasome subunit beta. (229 aa)
fndc3aFibronectin type III domain containing 3A. (1237 aa)
maml3Mastermind-like transcriptional coactivator 3. (1151 aa)
cbfbCore-binding factor subunit beta. (182 aa)
LOC102296334Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (226 aa)
LOC102298276Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (792 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (310 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa)
psme3Proteasome activator subunit 3. (256 aa)
hes1Hairy-related 6. (292 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (957 aa)
psma5Proteasome subunit alpha type. (241 aa)
LOC102293257Uncharacterized protein. (2253 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (504 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
psmd8Proteasome 26S subunit, non-ATPase 8. (265 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (332 aa)
psma2Proteasome endopeptidase complex. (164 aa)
tcf7l1Transcription factor 7 like 1b. (581 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
ccnd1Cyclin D1; Belongs to the cyclin family. (292 aa)
snw1SNW domain containing 1. (536 aa)
psme2Proteasome activator subunit 2. (245 aa)
smurf1E3 ubiquitin-protein ligase. (733 aa)
TEAD1TEA domain family member 1b. (435 aa)
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (668 aa)
ENSHBUP00000030562Uncharacterized protein. (733 aa)
ENSHBUP00000030614Uncharacterized protein. (95 aa)
lef1Lymphoid enhancer-binding factor 1. (398 aa)
LOC102306633CREB binding protein a. (2475 aa)
LOC102314666Ubiquitin-like domain-containing protein. (131 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
psmd226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (906 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (378 aa)
psme1Proteasome activator subunit 1. (230 aa)
runx3Runt-related transcription factor. (421 aa)
tcf7Transcription factor 7. (409 aa)
rbpjlRecombination signal binding protein for immunoglobulin kappa J region-like. (496 aa)
ctnnb1Catenin (cadherin-associated protein), beta 1. (783 aa)
zfhx4Zinc finger homeobox 4. (3771 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (448 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.