19 items (Haplochromis burtoni) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	coq9	Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (332 aa)
	ENSHBUP00000033403	Mab-21 domain-containing protein. (579 aa)
	gchfr	GTP cyclohydrolase I feedback regulator. (177 aa)
	idh1	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
	coq5	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (321 aa)
	pts	6-pyruvoyltetrahydropterin synthase. (152 aa)
	LOC102304432	GTP cyclohydrolase 2. (221 aa)
	LOC102312058	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (729 aa)
	coq7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (222 aa)
	coq6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (477 aa)
	spr	Sepiapterin reductase b. (267 aa)
	LOC102312375	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1. (724 aa)
	itprip	Inositol 1,4,5-trisphosphate receptor interacting protein. (537 aa)
	pdss2	Prenyl (decaprenyl) diphosphate synthase, subunit 2; Belongs to the FPP/GGPP synthase family. (385 aa)
	ENSHBUP00000013815	GTP cyclohydrolase 1. (173 aa)
	coq3	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (338 aa)
	pdss1	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family. (416 aa)
	LOC102296098	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	LOC102301101	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHBUP00000013815	LOC102304432	ENSHBUP00000013815	ENSHBUP00000021340	GTP cyclohydrolase 1.	GTP cyclohydrolase 2.	0.832
ENSHBUP00000013815	coq6	ENSHBUP00000013815	ENSHBUP00000017714	GTP cyclohydrolase 1.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.638
ENSHBUP00000013815	gchfr	ENSHBUP00000013815	ENSHBUP00000030930	GTP cyclohydrolase 1.	GTP cyclohydrolase I feedback regulator.	0.978
ENSHBUP00000013815	pts	ENSHBUP00000013815	ENSHBUP00000024866	GTP cyclohydrolase 1.	6-pyruvoyltetrahydropterin synthase.	0.929
ENSHBUP00000013815	spr	ENSHBUP00000013815	ENSHBUP00000017415	GTP cyclohydrolase 1.	Sepiapterin reductase b.	0.603
ENSHBUP00000033403	coq3	ENSHBUP00000033403	ENSHBUP00000013762	Mab-21 domain-containing protein.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.929
ENSHBUP00000033403	coq5	ENSHBUP00000033403	ENSHBUP00000027246	Mab-21 domain-containing protein.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.912
ENSHBUP00000033403	coq6	ENSHBUP00000033403	ENSHBUP00000017714	Mab-21 domain-containing protein.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.769
ENSHBUP00000033403	coq9	ENSHBUP00000033403	ENSHBUP00000035052	Mab-21 domain-containing protein.	Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.	0.928
ENSHBUP00000033403	pdss1	ENSHBUP00000033403	ENSHBUP00000013133	Mab-21 domain-containing protein.	Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family.	0.491
ENSHBUP00000033403	pdss2	ENSHBUP00000033403	ENSHBUP00000015037	Mab-21 domain-containing protein.	Prenyl (decaprenyl) diphosphate synthase, subunit 2; Belongs to the FPP/GGPP synthase family.	0.473
LOC102296098	LOC102312058	ENSHBUP00000011927	ENSHBUP00000020100	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	0.803
LOC102296098	LOC102312375	ENSHBUP00000011927	ENSHBUP00000016703	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	0.803
LOC102296098	spr	ENSHBUP00000011927	ENSHBUP00000017415	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Sepiapterin reductase b.	0.708
LOC102301101	LOC102312058	ENSHBUP00000005571	ENSHBUP00000020100	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	0.803
LOC102301101	LOC102312375	ENSHBUP00000005571	ENSHBUP00000016703	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	0.803
LOC102301101	spr	ENSHBUP00000005571	ENSHBUP00000017415	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Sepiapterin reductase b.	0.708
LOC102304432	ENSHBUP00000013815	ENSHBUP00000021340	ENSHBUP00000013815	GTP cyclohydrolase 2.	GTP cyclohydrolase 1.	0.832
LOC102304432	coq6	ENSHBUP00000021340	ENSHBUP00000017714	GTP cyclohydrolase 2.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.638
LOC102304432	gchfr	ENSHBUP00000021340	ENSHBUP00000030930	GTP cyclohydrolase 2.	GTP cyclohydrolase I feedback regulator.	0.978