19 items (Haplochromis burtoni) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	LOC102290684	Serine/threonine-protein phosphatase. (309 aa)
	ctsb	Cathepsin Bb; Belongs to the peptidase C1 family. (329 aa)
	LOC102309907	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (456 aa)
	LOC102296947	Uncharacterized protein. (303 aa)
	cul1	Cullin 1b; Belongs to the cullin family. (740 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	skp1	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
	LOC102313950	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (866 aa)
	adcy7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1086 aa)
	LOC102300580	RAB11a, member RAS oncogene family. (230 aa)
	ctsd	Cathepsin D; Belongs to the peptidase A1 family. (396 aa)
	egfr	Receptor protein-tyrosine kinase. (1120 aa)
	rpl8	Ribosomal protein L8. (257 aa)
	gas1	Growth arrest-specific 1a. (253 aa)
	EEF1A1-2	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
	megf11	Multiple EGF-like-domains 11. (1126 aa)
	LOC102292629	Uncharacterized protein. (266 aa)
	CSK	Tyrosine-protein kinase. (451 aa)
	ccne1	Cyclin E1; Belongs to the cyclin family. (462 aa)

Your Current Organism:

Haplochromis burtoni

NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSK	LOC102290684	ENSHBUP00000033741	ENSHBUP00000001048	Tyrosine-protein kinase.	Serine/threonine-protein phosphatase.	0.642
CSK	LOC102300580	ENSHBUP00000033741	ENSHBUP00000020747	Tyrosine-protein kinase.	RAB11a, member RAS oncogene family.	0.622
CSK	LOC102313950	ENSHBUP00000033741	ENSHBUP00000019474	Tyrosine-protein kinase.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.569
CSK	adcy7	ENSHBUP00000033741	ENSHBUP00000019480	Tyrosine-protein kinase.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.526
CSK	ccne1	ENSHBUP00000033741	ENSHBUP00000034171	Tyrosine-protein kinase.	Cyclin E1; Belongs to the cyclin family.	0.738
CSK	cul1	ENSHBUP00000033741	ENSHBUP00000017087	Tyrosine-protein kinase.	Cullin 1b; Belongs to the cullin family.	0.435
CSK	egfr	ENSHBUP00000033741	ENSHBUP00000027041	Tyrosine-protein kinase.	Receptor protein-tyrosine kinase.	0.642
CSK	megf11	ENSHBUP00000033741	ENSHBUP00000028875	Tyrosine-protein kinase.	Multiple EGF-like-domains 11.	0.572
CSK	ppp2ca	ENSHBUP00000033741	ENSHBUP00000019070	Tyrosine-protein kinase.	Serine/threonine-protein phosphatase.	0.701
CSK	skp1	ENSHBUP00000033741	ENSHBUP00000019095	Tyrosine-protein kinase.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.683
EEF1A1-2	LOC102290684	ENSHBUP00000028109	ENSHBUP00000001048	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Serine/threonine-protein phosphatase.	0.424
EEF1A1-2	LOC102292629	ENSHBUP00000028109	ENSHBUP00000031449	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Uncharacterized protein.	0.614
EEF1A1-2	LOC102296947	ENSHBUP00000028109	ENSHBUP00000015164	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Uncharacterized protein.	0.666
EEF1A1-2	LOC102309907	ENSHBUP00000028109	ENSHBUP00000013692	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.799
EEF1A1-2	rpl8	ENSHBUP00000028109	ENSHBUP00000027526	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Ribosomal protein L8.	0.852
LOC102290684	CSK	ENSHBUP00000001048	ENSHBUP00000033741	Serine/threonine-protein phosphatase.	Tyrosine-protein kinase.	0.642
LOC102290684	EEF1A1-2	ENSHBUP00000001048	ENSHBUP00000028109	Serine/threonine-protein phosphatase.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.424
LOC102290684	LOC102300580	ENSHBUP00000001048	ENSHBUP00000020747	Serine/threonine-protein phosphatase.	RAB11a, member RAS oncogene family.	0.571
LOC102290684	LOC102313950	ENSHBUP00000001048	ENSHBUP00000019474	Serine/threonine-protein phosphatase.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.417
LOC102290684	ccne1	ENSHBUP00000001048	ENSHBUP00000034171	Serine/threonine-protein phosphatase.	Cyclin E1; Belongs to the cyclin family.	0.597