STRINGSTRING
LOC102296059 LOC102296059 LOC102306195 LOC102306195 ELK3 ELK3 plcg1 plcg1 map2k2 map2k2 btc btc LOC102309252 LOC102309252 LOC102294942 LOC102294942 erbb2 erbb2 pik3r1 pik3r1 LOC102301101 LOC102301101 camk2a camk2a LOC102296758 LOC102296758 LOC102296588 LOC102296588 shc2 shc2 crk crk erbb3 erbb3 LOC102293191 LOC102293191 ENSHBUP00000007276 ENSHBUP00000007276 ENSHBUP00000007353 ENSHBUP00000007353 LOC102289537 LOC102289537 LOC102297714 LOC102297714 LOC102288843 LOC102288843 ENSHBUP00000008836 ENSHBUP00000008836 LOC102303337 LOC102303337 LOC102293296 LOC102293296 tmeff1 tmeff1 ENSHBUP00000009952 ENSHBUP00000009952 LOC102289590 LOC102289590 LOC102305228 LOC102305228 ptk2 ptk2 SHC4 SHC4 LOC102295102 LOC102295102 LOC102311605 LOC102311605 LOC102296098 LOC102296098 REM1 REM1 araf araf LOC102303266 LOC102303266 crkl crkl cdkn1b cdkn1b LOC102290252 LOC102290252 nrg4 nrg4 prkca prkca jun jun myc myc pak6 pak6 gem gem akt1 akt1 PRKCB PRKCB ENSHBUP00000014471 ENSHBUP00000014471 bad bad ppp1r14b ppp1r14b cbl cbl LOC102313643 LOC102313643 braf braf ENSHBUP00000016109 ENSHBUP00000016109 SHC3 SHC3 LOC102309393 LOC102309393 plcg2 plcg2 LOC102307400 LOC102307400 elk1 elk1 CSDE1 CSDE1 LOC102291632 LOC102291632 ENSHBUP00000018527 ENSHBUP00000018527 LOC102302192 LOC102302192 abl2 abl2 pik3cd pik3cd ENSHBUP00000019125 ENSHBUP00000019125 LOC102305748 LOC102305748 ENSHBUP00000019390 ENSHBUP00000019390 LOC102306161 LOC102306161 LOC102305789 LOC102305789 PAK3 PAK3 abl1 abl1 pik3cb pik3cb LOC102291189 LOC102291189 nck2 nck2 LOC102298036 LOC102298036 LOC102301891 LOC102301891 pak4 pak4 LOC102309899 LOC102309899 ENSHBUP00000022085 ENSHBUP00000022085 rrad rrad ENSHBUP00000022635 ENSHBUP00000022635 shc1 shc1 LOC102308224 LOC102308224 LOC102292440 LOC102292440 LOC102304719 LOC102304719 LOC102304206 LOC102304206 LOC102295027 LOC102295027 mapk1 mapk1 ENSHBUP00000024997 ENSHBUP00000024997 LOC102293267 LOC102293267 LOC102313924 LOC102313924 gab1 gab1 egfr egfr LOC102289393 LOC102289393 LOC102288968 LOC102288968 LOC102289283 LOC102289283 alkbh4 alkbh4 hras hras ENSHBUP00000028406 ENSHBUP00000028406 map2k1 map2k1 LOC102304961 LOC102304961 LOC102296178 LOC102296178 KRAS KRAS LOC102298669 LOC102298669 LOC102306909 LOC102306909 LOC102294556 LOC102294556 pik3r2 pik3r2 LOC102293792 LOC102293792 sos1 sos1 nck1 nck1 ENSHBUP00000031317 ENSHBUP00000031317 pak5 pak5 LOC102293459 LOC102293459 LOC102304410 LOC102304410 sos2 sos2 LOC102295366 LOC102295366 ENSHBUP00000032271 ENSHBUP00000032271 mtor mtor LOC102310457 LOC102310457 LOC102297038 LOC102297038 LOC102312420 LOC102312420 tmeff2 tmeff2 raf1 raf1 ENSHBUP00000034273 ENSHBUP00000034273 grb2 grb2 LOC102297192 LOC102297192 pak1 pak1 LOC102294714 LOC102294714 egf egf LOC102295710 LOC102295710 nrg2 nrg2 LOC102304538 LOC102304538 LOC102304617 LOC102304617 map2k7 map2k7 SRC SRC gsk3b gsk3b ENSHBUP00000002891 ENSHBUP00000002891 LOC102292733 LOC102292733 pik3ca pik3ca LOC102306852 LOC102306852
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102296059GRB2 related adaptor protein 2a. (290 aa)
LOC102306195Neuregulin 3b. (657 aa)
ELK3ETS transcription factor ELK3. (403 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (425 aa)
btcBetacellulin, epidermal growth factor family member. (172 aa)
LOC102309252Uncharacterized protein. (123 aa)
LOC102294942Uncharacterized protein. (588 aa)
erbb2Receptor protein-tyrosine kinase. (1309 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (729 aa)
LOC102301101Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
camk2aCalcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (460 aa)
LOC102296758Tyrosine-protein kinase. (590 aa)
LOC102296588ETS domain-containing protein. (394 aa)
shc2SHC (Src homology 2 domain containing) transforming protein 2. (725 aa)
crkCRK proto-oncogene, adaptor protein. (315 aa)
erbb3Protein kinase domain-containing protein. (1151 aa)
LOC102293191P21 protein (Cdc42/Rac)-activated kinase 6b. (286 aa)
ENSHBUP00000007276Receptor protein-tyrosine kinase. (587 aa)
ENSHBUP00000007353Kazal-like domain-containing protein. (100 aa)
LOC102289537GRB2 related adaptor protein 2b. (227 aa)
LOC102297714Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2; Belongs to the protein kinase superfamily. (344 aa)
LOC102288843Protein kinase domain-containing protein. (616 aa)
ENSHBUP00000008836Uncharacterized protein. (394 aa)
LOC102303337Heparin-binding EGF-like growth factor a. (239 aa)
LOC102293296Protein kinase domain-containing protein. (264 aa)
tmeff1Transmembrane protein with EGF-like and two follistatin-like domains 1a. (250 aa)
ENSHBUP00000009952PH domain-containing protein. (146 aa)
LOC102289590Amphiregulin. (233 aa)
LOC102305228Uncharacterized protein. (857 aa)
ptk2Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family. (980 aa)
SHC4SHC adaptor protein 4. (588 aa)
LOC102295102Uncharacterized protein. (319 aa)
LOC102311605Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2. (543 aa)
LOC102296098Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
REM1RRAD and GEM like GTPase 1. (308 aa)
arafA-Raf proto-oncogene, serine/threonine kinase. (611 aa)
LOC102303266Phosphoinositide-3-kinase, regulatory subunit 3a (gamma). (467 aa)
crklV-crk avian sarcoma virus CT10 oncogene homolog-like. (305 aa)
cdkn1bCyclin-dependent kinase inhibitor 1Bb. (184 aa)
LOC102290252JunE proto-oncogene, AP-1 transcription factor subunit. (347 aa)
nrg4EGF-like domain-containing protein. (109 aa)
prkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
junBZIP domain-containing protein; Belongs to the bZIP family. (323 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (412 aa)
pak6Non-specific serine/threonine protein kinase. (698 aa)
gemGTP binding protein overexpressed in skeletal muscle. (307 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
ENSHBUP00000014471Uncharacterized protein. (97 aa)
badBCL2 associated agonist of cell death b. (158 aa)
ppp1r14bProtein phosphatase 1, regulatory (inhibitor) subunit 14Bb. (133 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (950 aa)
LOC102313643Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (428 aa)
brafB-Raf proto-oncogene, serine/threonine kinase. (822 aa)
ENSHBUP00000016109Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (261 aa)
SHC3SHC adaptor protein 3. (666 aa)
LOC102309393Myelocytomatosis oncogene homolog. (356 aa)
plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1249 aa)
LOC102307400Zgc:55558. (187 aa)
elk1ETS transcription factor ELK1. (595 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (922 aa)
LOC102291632Signal transducer and activator of transcription. (786 aa)
ENSHBUP00000018527EGF-like domain-containing protein. (102 aa)
LOC102302192Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
abl2Tyrosine-protein kinase. (1201 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa)
ENSHBUP00000019125Kazal-like domain-containing protein. (67 aa)
LOC102305748Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1; Belongs to the protein kinase superfamily. (486 aa)
ENSHBUP00000019390Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (284 aa)
LOC102306161Mitogen-activated protein kinase kinase 2b. (397 aa)
LOC102305789Transforming growth factor, alpha. (254 aa)
PAK3Non-specific serine/threonine protein kinase. (575 aa)
abl1Tyrosine-protein kinase. (1104 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
LOC102291189Mitogen-activated protein kinase. (456 aa)
nck2Cytoplasmic protein. (398 aa)
LOC102298036Eukaryotic translation initiation factor 4E binding protein 1. (119 aa)
LOC102301891Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (470 aa)
pak4Non-specific serine/threonine protein kinase. (660 aa)
LOC102309899Signal transducer and activator of transcription. (786 aa)
ENSHBUP00000022085Recep_L_domain domain-containing protein. (166 aa)
rradRas-related associated with diabetes. (309 aa)
ENSHBUP00000022635Cyclin-dependent kinase inhibitor 1A. (163 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (600 aa)
LOC102308224Mitogen-activated protein kinase. (435 aa)
LOC102292440Receptor protein-tyrosine kinase. (1405 aa)
LOC102304719Uncharacterized protein. (181 aa)
LOC102304206Erb-b2 receptor tyrosine kinase 3b. (1464 aa)
LOC102295027Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (503 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
ENSHBUP00000024997Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (292 aa)
LOC102293267Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (362 aa)
LOC102313924Neuregulin 1. (626 aa)
gab1GRB2-associated binding protein 1. (746 aa)
egfrReceptor protein-tyrosine kinase. (1120 aa)
LOC102289393PH domain-containing protein. (543 aa)
LOC102288968Epithelial mitogen homolog (mouse). (164 aa)
LOC102289283EGF-like domain-containing protein. (154 aa)
alkbh4AlkB homolog 4, lysine demthylase. (275 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
ENSHBUP00000028406Protein kinase domain-containing protein. (93 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
LOC102304961Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
LOC102296178Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (388 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (217 aa)
LOC102298669Receptor protein-tyrosine kinase. (1116 aa)
LOC102306909Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa)
LOC102294556Non-specific serine/threonine protein kinase. (513 aa)
pik3r2Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (735 aa)
LOC102293792Uncharacterized protein. (498 aa)
sos1Son of sevenless homolog 1 (Drosophila). (1153 aa)
nck1Cytoplasmic protein. (463 aa)
ENSHBUP00000031317P21 protein (Cdc42/Rac)-activated kinase 2b. (157 aa)
pak5Non-specific serine/threonine protein kinase. (782 aa)
LOC102293459Uncharacterized protein. (244 aa)
LOC102304410Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
sos2Son of sevenless homolog 2 (Drosophila). (1331 aa)
LOC102295366Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (526 aa)
ENSHBUP00000032271Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2; Belongs to the protein kinase superfamily. (435 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2516 aa)
LOC102310457Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (607 aa)
LOC102297038Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (445 aa)
LOC1023124201-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1312 aa)
tmeff2Transmembrane protein with EGF-like and two follistatin-like domains 2a. (380 aa)
raf1Raf-1 proto-oncogene, serine/threonine kinase a. (670 aa)
ENSHBUP00000034273Zgc:158659; Belongs to the PI3/PI4-kinase family. (485 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC102297192Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
pak1Non-specific serine/threonine protein kinase. (583 aa)
LOC102294714Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (956 aa)
egfEpidermal growth factor. (1159 aa)
LOC102295710Mitogen-activated protein kinase. (390 aa)
nrg2Neuregulin 2b. (712 aa)
LOC102304538Mitogen-activated protein kinase. (420 aa)
LOC102304617Cyclin-dependent kinase inhibitor 1A. (169 aa)
map2k7Mitogen-activated protein kinase kinase 7. (453 aa)
SRCTyrosine-protein kinase. (550 aa)
gsk3bGlycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (421 aa)
ENSHBUP00000002891UBA domain-containing protein. (163 aa)
LOC102292733Neuregulin 2a. (681 aa)
pik3caPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC102306852Uncharacterized protein. (178 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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