STRINGSTRING
rptor rptor atg3 atg3 LOC102290684 LOC102290684 gabarap gabarap ttc14 ttc14 LOC102304444 LOC102304444 ppp2cb ppp2cb pik3r4 pik3r4 atg16l1 atg16l1 pik3c3 pik3c3 LOC102306046 LOC102306046 atg2a atg2a atg12 atg12 LOC102295665 LOC102295665 atg13 atg13 ENSHBUP00000015287 ENSHBUP00000015287 atg101 atg101 ATG2B ATG2B igbp1 igbp1 mlst8 mlst8 atg4c atg4c atg4d atg4d ulk3 ulk3 ppp2ca ppp2ca LOC102302824 LOC102302824 becn1 becn1 atg9a atg9a ulk2 ulk2 LOC102292286 LOC102292286 atg7 atg7 atg4b atg4b atg10 atg10 wipi2 wipi2 atg5 atg5 mtor mtor WIPI1 WIPI1 gabarapl2 gabarapl2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rptorRegulatory associated protein of MTOR, complex 1. (1358 aa)
atg3Autophagy-related protein 3. (313 aa)
LOC102290684Serine/threonine-protein phosphatase. (309 aa)
gabarapGABA(A) receptor-associated protein b. (122 aa)
ttc14Tetratricopeptide repeat domain 14. (723 aa)
LOC102304444Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (500 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
pik3r4Phosphoinositide-3-kinase, regulatory subunit 4. (1336 aa)
atg16l1ATG16 autophagy related 16-like 1 (S. cerevisiae). (604 aa)
pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (884 aa)
LOC102306046Si:ch211-63o20.7; Belongs to the protein kinase superfamily. (348 aa)
atg2aAutophagy related 2A. (2014 aa)
atg12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (117 aa)
LOC102295665Zgc:92606. (117 aa)
atg13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (538 aa)
ENSHBUP00000015287Si:ch1073-143l10.2. (137 aa)
atg101Autophagy related 101. (218 aa)
ATG2BAutophagy related 2B. (2073 aa)
igbp1Immunoglobulin (CD79A) binding protein 1. (358 aa)
mlst8MTOR associated protein, LST8 homolog (S. cerevisiae). (326 aa)
atg4cCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (480 aa)
atg4dCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (459 aa)
ulk3Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (469 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
LOC102302824GABA type A receptor associated protein like 2. (121 aa)
becn1Beclin 1, autophagy related. (447 aa)
atg9aAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (855 aa)
ulk2Unc-51 like autophagy activating kinase 2. (1039 aa)
LOC102292286Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (809 aa)
atg7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (720 aa)
atg4bCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (394 aa)
atg10Autophagy_act_C domain-containing protein. (226 aa)
wipi2WD repeat domain, phosphoinositide interacting 2. (427 aa)
atg5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2516 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (443 aa)
gabarapl2GABA(A) receptor-associated protein like 2. (117 aa)
Your Current Organism:
Haplochromis burtoni
NCBI taxonomy Id: 8153
Other names: Astatotilapia burtoni, Chromis burtoni, H. burtoni
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