(36 nodes) Arachidonic acid metabolic process, and Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) network (Astatotilapia calliptera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113024448	Cytochrome P450, family 3, subfamily A, polypeptide 65. (497 aa)
	ENSACLP00000004294	Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (524 aa)
	ENSACLP00000004483	Uncharacterized protein. (627 aa)
	ENSACLP00000006656	Uncharacterized protein; Belongs to the cytochrome P450 family. (455 aa)
	LOC113016270	Uncharacterized protein; Belongs to the cytochrome P450 family. (535 aa)
	ENSACLP00000007632	Uncharacterized protein. (333 aa)
	ENSACLP00000009028	Uncharacterized protein. (261 aa)
	ENSACLP00000009577	Uncharacterized protein. (486 aa)
	ENSACLP00000010307	Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
	ENSACLP00000010498	Uncharacterized protein. (586 aa)
	LOC113016255	Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
	ENSACLP00000013883	Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
	ENSACLP00000014324	Uncharacterized protein; Belongs to the cytochrome P450 family. (505 aa)
	LOC113016261	Uncharacterized protein. (493 aa)
	LOC113016263	Uncharacterized protein. (493 aa)
	LOC113016262	Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
	ALOX15B	Arachidonate 15-lipoxygenase type B. (615 aa)
	ENSACLP00000015230	Uncharacterized protein; Belongs to the cytochrome P450 family. (500 aa)
	ENSACLP00000015700	Uncharacterized protein; Belongs to the cytochrome P450 family. (500 aa)
	LOC113016277	Uncharacterized protein; Belongs to the cytochrome P450 family. (535 aa)
	LOC113016319	Uncharacterized protein; Belongs to the cytochrome P450 family. (534 aa)
	ENSACLP00000015957	Uncharacterized protein. (71 aa)
	alox5	Arachidonate 5-lipoxygenase a. (674 aa)
	LOC113015599	Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
	ENSACLP00000016607	Cytochrome P450, family 1, subfamily D, polypeptide 1; Belongs to the cytochrome P450 family. (606 aa)
	LOC113015601	Cytochrome P450, family 2, subfamily N, polypeptide 13; Belongs to the cytochrome P450 family. (483 aa)
	LOC113015600	Cytochrome P450, family 2, subfamily N, polypeptide 13; Belongs to the cytochrome P450 family. (495 aa)
	ENSACLP00000016649	Cytochrome P450, family 2, subfamily N, polypeptide 13; Belongs to the cytochrome P450 family. (495 aa)
	ENSACLP00000023119	Uncharacterized protein. (324 aa)
	LOC113018260	Arachidonate 12-lipoxygenase. (670 aa)
	ENSACLP00000026705	Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. (481 aa)
	LOC113024290	Uncharacterized protein. (667 aa)
	LOC113024298	Cytochrome P450, family 2, subfamily U, polypeptide 1; Belongs to the cytochrome P450 family. (525 aa)
	ENSACLP00000035974	Uncharacterized protein; Belongs to the cytochrome P450 family. (455 aa)
	ENSACLP00000036086	Uncharacterized protein; Belongs to the cytochrome P450 family. (501 aa)
	ENSACLP00000037360	Epoxide hydrolase 5. (488 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALOX15B	ENSACLP00000006656	ENSACLP00000015101	ENSACLP00000006656	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.517
ALOX15B	ENSACLP00000007632	ENSACLP00000015101	ENSACLP00000007632	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein.	0.541
ALOX15B	ENSACLP00000009577	ENSACLP00000015101	ENSACLP00000009577	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein.	0.471
ALOX15B	ENSACLP00000010307	ENSACLP00000015101	ENSACLP00000010307	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.471
ALOX15B	ENSACLP00000013883	ENSACLP00000015101	ENSACLP00000013883	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.471
ALOX15B	ENSACLP00000014324	ENSACLP00000015101	ENSACLP00000014324	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.471
ALOX15B	ENSACLP00000015230	ENSACLP00000015101	ENSACLP00000015230	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.471
ALOX15B	ENSACLP00000015700	ENSACLP00000015101	ENSACLP00000015700	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.471
ALOX15B	ENSACLP00000015957	ENSACLP00000015101	ENSACLP00000015957	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein.	0.541
ALOX15B	ENSACLP00000016649	ENSACLP00000015101	ENSACLP00000016649	Arachidonate 15-lipoxygenase type B.	Cytochrome P450, family 2, subfamily N, polypeptide 13; Belongs to the cytochrome P450 family.	0.471
ALOX15B	ENSACLP00000035974	ENSACLP00000015101	ENSACLP00000035974	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.517
ALOX15B	ENSACLP00000036086	ENSACLP00000015101	ENSACLP00000036086	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.517
ALOX15B	LOC113015599	ENSACLP00000015101	ENSACLP00000016539	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.471
ALOX15B	LOC113015600	ENSACLP00000015101	ENSACLP00000016642	Arachidonate 15-lipoxygenase type B.	Cytochrome P450, family 2, subfamily N, polypeptide 13; Belongs to the cytochrome P450 family.	0.471
ALOX15B	LOC113015601	ENSACLP00000015101	ENSACLP00000016622	Arachidonate 15-lipoxygenase type B.	Cytochrome P450, family 2, subfamily N, polypeptide 13; Belongs to the cytochrome P450 family.	0.471
ALOX15B	LOC113016255	ENSACLP00000015101	ENSACLP00000013641	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.471
ALOX15B	LOC113016261	ENSACLP00000015101	ENSACLP00000014459	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein.	0.516
ALOX15B	LOC113016262	ENSACLP00000015101	ENSACLP00000014805	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.516
ALOX15B	LOC113016263	ENSACLP00000015101	ENSACLP00000014567	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein.	0.516
ALOX15B	LOC113016270	ENSACLP00000015101	ENSACLP00000007536	Arachidonate 15-lipoxygenase type B.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.541