STRINGSTRING
ENSACLP00000000986 ENSACLP00000000986 pole3 pole3 rfc4 rfc4 ENSACLP00000001994 ENSACLP00000001994 pole4 pole4 rfc3 rfc3 lig1 lig1 ENSACLP00000007406 ENSACLP00000007406 ENSACLP00000009814 ENSACLP00000009814 dna2 dna2 wdhd1 wdhd1 ENSACLP00000013892 ENSACLP00000013892 rfc2 rfc2 pcna pcna recql4 recql4 ENSACLP00000020901 ENSACLP00000020901 rfc1 rfc1 fen1 fen1 rfc5 rfc5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSACLP00000000986DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2036 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (150 aa)
rfc4Replication factor C (activator 1) 4. (357 aa)
ENSACLP00000001994ATPase family AAA domain containing 5a. (1510 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
lig1DNA ligase. (1014 aa)
ENSACLP00000007406Exonuclease 1. (775 aa)
ENSACLP00000009814AAA domain-containing protein. (866 aa)
dna2DNA replication helicase/nuclease 2. (1417 aa)
wdhd1WD repeat and HMG-box DNA binding protein 1. (1134 aa)
ENSACLP00000013892Zgc:110269. (354 aa)
rfc2Replication factor C (activator 1) 2. (356 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
recql4RecQ helicase-like 4. (1577 aa)
ENSACLP00000020901DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (499 aa)
rfc1Replication factor C subunit 1. (1161 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (381 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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