STRINGSTRING
hsdl1 hsdl1 ENSACLP00000002513 ENSACLP00000002513 LOC113032285 LOC113032285 LOC113023525 LOC113023525 LOC113009035 LOC113009035 ENSACLP00000005892 ENSACLP00000005892 LOC113035327 LOC113035327 ENSACLP00000009717 ENSACLP00000009717 LOC113026644 LOC113026644 ENSACLP00000014369 ENSACLP00000014369 srd5a1 srd5a1 ENSACLP00000022184 ENSACLP00000022184 ENSACLP00000022967 ENSACLP00000022967 srd5a3 srd5a3 LOC113026744 LOC113026744 ENSACLP00000025139 ENSACLP00000025139 LOC113007739 LOC113007739 ENSACLP00000026689 ENSACLP00000026689 LOC113020014 LOC113020014 LOC113019472 LOC113019472 ENSACLP00000030400 ENSACLP00000030400 ENSACLP00000032688 ENSACLP00000032688 LOC113022938 LOC113022938 LOC113016943 LOC113016943 LOC113016287 LOC113016287 LOC113026834 LOC113026834 srd5a2 srd5a2 AKR1D1 AKR1D1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hsdl1Hydroxysteroid dehydrogenase like 1. (325 aa)
ENSACLP00000002513Uncharacterized protein; Belongs to the cytochrome P450 family. (145 aa)
LOC113032285Cytochrome P450, family 21, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (525 aa)
LOC1130235253-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (249 aa)
LOC113009035Aldo_ket_red domain-containing protein. (326 aa)
ENSACLP00000005892Aldo_ket_red domain-containing protein. (267 aa)
LOC113035327Cytochrome P450, family 17, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (516 aa)
ENSACLP00000009717UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (558 aa)
LOC113026644Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
ENSACLP00000014369Uncharacterized protein. (478 aa)
srd5a13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (265 aa)
ENSACLP00000022184Hydroxysteroid (17-beta) dehydrogenase 3. (319 aa)
ENSACLP00000022967UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (527 aa)
srd5a3Steroid 5 alpha-reductase 3. (344 aa)
LOC113026744Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (518 aa)
ENSACLP00000025139Uncharacterized protein. (283 aa)
LOC113007739Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. (374 aa)
ENSACLP00000026689UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
LOC113020014Cytochrome P450, family 19, subfamily A, polypeptide 1a; Belongs to the cytochrome P450 family. (506 aa)
LOC113019472Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (521 aa)
ENSACLP00000030400Cytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (542 aa)
ENSACLP00000032688Aldo_ket_red domain-containing protein. (186 aa)
LOC113022938Zgc:113054. (551 aa)
LOC113016943Hydroxysteroid (11-beta) dehydrogenase 1-like a. (286 aa)
LOC113016287Hydroxysteroid (11-beta) dehydrogenase 1-like a. (287 aa)
LOC113026834Hydroxysteroid (11-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (406 aa)
srd5a23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (251 aa)
AKR1D1Aldo-keto reductase family 1 member D1. (354 aa)
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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