(73 nodes) Glycosaminoglycan degradation, and Sulfation network (Astatotilapia calliptera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113036545	Beta-galactosidase. (605 aa)
	naglu	N-acetylglucosaminidase, alpha. (752 aa)
	LOC113006395	Deoxyribonuclease II beta. (351 aa)
	LOC113006511	Uncharacterized protein. (361 aa)
	ENSACLP00000002721	Sulfatase modifying factor 1. (281 aa)
	sult6b1	Sulfotransferase; Belongs to the sulfotransferase 1 family. (301 aa)
	gla	Alpha-galactosidase. (430 aa)
	LOC113011071	Sulfatase domain-containing protein. (763 aa)
	ENSACLP00000004789	Uncharacterized protein. (343 aa)
	ENSACLP00000005566	Uncharacterized protein. (851 aa)
	ENSACLP00000005626	Uncharacterized protein. (172 aa)
	LOC113030553	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (640 aa)
	arsj	Arylsulfatase family, member J. (566 aa)
	LOC113031247	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (647 aa)
	sumf2	Sulfatase modifying factor 2. (295 aa)
	ENSACLP00000010055	Arylsulfatase family, member K. (551 aa)
	LOC113015035	Neuraminidase 1. (386 aa)
	LOC113015104	Neuraminidase 1. (387 aa)
	bod1	Uncharacterized protein. (426 aa)
	ENSACLP00000012030	Steroid sulfatase (microsomal), isozyme S. (536 aa)
	LOC113017976	Sulfotransferase; Belongs to the sulfotransferase 1 family. (293 aa)
	ENSACLP00000012420	Uncharacterized protein. (264 aa)
	LOC113026160	Uncharacterized protein. (504 aa)
	LOC113027391	Uncharacterized protein. (389 aa)
	dnase2	Deoxyribonuclease II, lysosomal. (374 aa)
	LOC113036391	Arylsulfatase family, member Ia. (570 aa)
	hpse2	Heparanase 2. (622 aa)
	LOC113019334	Sulfotransferase; Belongs to the sulfotransferase 1 family. (309 aa)
	ENSACLP00000015106	Sulfotransferase; Belongs to the sulfotransferase 1 family. (159 aa)
	ENSACLP00000015626	Heparanase. (539 aa)
	ENSACLP00000017040	Uncharacterized protein. (846 aa)
	LOC113024118	Heparan-alpha-glucosaminide N-acetyltransferase. (651 aa)
	LOC113024869	Uncharacterized protein. (1648 aa)
	arsg	Arylsulfatase G. (539 aa)
	ENSACLP00000021360	Sulfotransferase; Belongs to the sulfotransferase 1 family. (363 aa)
	gns	N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (545 aa)
	ctsa	Carboxypeptidase; Belongs to the peptidase S10 family. (473 aa)
	LOC113025258	N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (524 aa)
	LOC113008083	Galactosidase, beta 1-like; Belongs to the glycosyl hydrolase 35 family. (636 aa)
	hexa	Beta-hexosaminidase. (536 aa)
	neu3	Sialidase 3 (membrane sialidase), tandem duplicate 1. (408 aa)
	LOC113007702	Arylsulfatase H. (597 aa)
	ENSACLP00000029641	Uncharacterized protein. (1806 aa)
	sgsh	N-sulfoglucosamine sulfohydrolase (sulfamidase). (527 aa)
	ENSACLP00000029854	Si:dkey-192p21.6. (565 aa)
	LOC113022875	Extracellular sulfatase. (884 aa)
	ENSACLP00000030182	Sulfotransferase; Belongs to the sulfotransferase 1 family. (289 aa)
	ENSACLP00000030769	Iduronidase alpha-L-. (633 aa)
	glb1	Beta-galactosidase. (643 aa)
	ENSACLP00000031301	Sulfotransferase; Belongs to the sulfotransferase 1 family. (310 aa)
	ENSACLP00000031438	Sulfotransferase; Belongs to the sulfotransferase 1 family. (255 aa)
	ENSACLP00000031458	Steroid sulfatase (microsomal), isozyme S. (477 aa)
	LOC113020267	Sulfotransferase; Belongs to the sulfotransferase 1 family. (281 aa)
	ENSACLP00000031869	annotation not available (255 aa)
	ids	Iduronate 2-sulfatase. (559 aa)
	ENSACLP00000032187	Sulfotransferase; Belongs to the sulfotransferase 1 family. (293 aa)
	LOC113020267-2	Amine sulfotransferase-like. (281 aa)
	LOC113020267-3	Amine sulfotransferase-like. (281 aa)
	LOC113020274	Sulfotransferase; Belongs to the sulfotransferase 1 family. (281 aa)
	ENSACLP00000033032	Sulfotransferase; Belongs to the sulfotransferase 1 family. (281 aa)
	ENSACLP00000033106	Sulfotransferase; Belongs to the sulfotransferase 1 family. (156 aa)
	LOC113027833	Sulfotransferase; Belongs to the sulfotransferase 1 family. (287 aa)
	ENSACLP00000036527	Uncharacterized protein. (304 aa)
	galns	Galactosamine (N-acetyl)-6-sulfatase. (525 aa)
	ENSACLP00000037214	Si:dkey-174i8.1. (403 aa)
	ENSACLP00000037243	Sulfatase domain-containing protein. (115 aa)
	LOC113020423	Sulfotransferase; Belongs to the sulfotransferase 1 family. (287 aa)
	sulf1	Sulfatase 1. (1163 aa)
	arsa	Arylsulfatase A. (499 aa)
	ENSACLP00000038367	Sulfatase domain-containing protein. (92 aa)
	ARSB	Arylsulfatase B. (485 aa)
	LOC113030966	Beta-galactosidase. (638 aa)
	ENSACLP00000040651	N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (534 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARSB	ENSACLP00000002721	ENSACLP00000038930	ENSACLP00000002721	Arylsulfatase B.	Sulfatase modifying factor 1.	0.730
ARSB	ENSACLP00000005566	ENSACLP00000038930	ENSACLP00000005566	Arylsulfatase B.	Uncharacterized protein.	0.519
ARSB	ENSACLP00000005626	ENSACLP00000038930	ENSACLP00000005626	Arylsulfatase B.	Uncharacterized protein.	0.519
ARSB	ENSACLP00000010055	ENSACLP00000038930	ENSACLP00000010055	Arylsulfatase B.	Arylsulfatase family, member K.	0.711
ARSB	ENSACLP00000012030	ENSACLP00000038930	ENSACLP00000012030	Arylsulfatase B.	Steroid sulfatase (microsomal), isozyme S.	0.715
ARSB	ENSACLP00000017040	ENSACLP00000038930	ENSACLP00000017040	Arylsulfatase B.	Uncharacterized protein.	0.451
ARSB	ENSACLP00000029854	ENSACLP00000038930	ENSACLP00000029854	Arylsulfatase B.	Si:dkey-192p21.6.	0.556
ARSB	ENSACLP00000030769	ENSACLP00000038930	ENSACLP00000030769	Arylsulfatase B.	Iduronidase alpha-L-.	0.897
ARSB	ENSACLP00000031458	ENSACLP00000038930	ENSACLP00000031458	Arylsulfatase B.	Steroid sulfatase (microsomal), isozyme S.	0.722
ARSB	ENSACLP00000038367	ENSACLP00000038930	ENSACLP00000038367	Arylsulfatase B.	Sulfatase domain-containing protein.	0.889
ARSB	ENSACLP00000040651	ENSACLP00000038930	ENSACLP00000040651	Arylsulfatase B.	N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.	0.459
ARSB	LOC113007702	ENSACLP00000038930	ENSACLP00000025867	Arylsulfatase B.	Arylsulfatase H.	0.718
ARSB	LOC113008083	ENSACLP00000038930	ENSACLP00000022500	Arylsulfatase B.	Galactosidase, beta 1-like; Belongs to the glycosyl hydrolase 35 family.	0.558
ARSB	LOC113015035	ENSACLP00000038930	ENSACLP00000010258	Arylsulfatase B.	Neuraminidase 1.	0.547
ARSB	LOC113015104	ENSACLP00000038930	ENSACLP00000010277	Arylsulfatase B.	Neuraminidase 1.	0.547
ARSB	LOC113022875	ENSACLP00000038930	ENSACLP00000030046	Arylsulfatase B.	Extracellular sulfatase.	0.458
ARSB	LOC113024118	ENSACLP00000038930	ENSACLP00000017606	Arylsulfatase B.	Heparan-alpha-glucosaminide N-acetyltransferase.	0.556
ARSB	LOC113025258	ENSACLP00000038930	ENSACLP00000021999	Arylsulfatase B.	N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.	0.467
ARSB	LOC113030553	ENSACLP00000038930	ENSACLP00000008631	Arylsulfatase B.	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	0.711
ARSB	LOC113030966	ENSACLP00000038930	ENSACLP00000039851	Arylsulfatase B.	Beta-galactosidase.	0.519