(21 nodes) Mixed, incl. Chromosome passenger complex, and Phosphorylation of Emi1 network (Astatotilapia calliptera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	espl1	Extra spindle pole bodies like 1, separase. (2169 aa)
	ENSACLP00000002506	Uncharacterized protein. (179 aa)
	LOC113035402	Cyclin B2; Belongs to the cyclin family. (386 aa)
	ENSACLP00000003678	TPX2 microtubule nucleation factor. (621 aa)
	LOC113008948	Aurora kinase B; Belongs to the protein kinase superfamily. (331 aa)
	ENSACLP00000006245	Protein kinase domain-containing protein. (194 aa)
	PLK1	Serine/threonine-protein kinase PLK. (582 aa)
	ENSACLP00000007272	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (276 aa)
	LOC113013372	Baculoviral IAP repeat containing 5b. (144 aa)
	cdca8	Cell division cycle associated 8. (278 aa)
	ENSACLP00000018315	Uncharacterized protein. (799 aa)
	LOC113031225	Cyclin A2; Belongs to the cyclin family. (440 aa)
	LOC113009944	Fizzy/cell division cycle 20 related 1b. (531 aa)
	LOC113028579	Baculoviral IAP repeat containing 5a. (142 aa)
	plk2	Serine/threonine-protein kinase PLK. (657 aa)
	aurka	Aurora kinase A; Belongs to the protein kinase superfamily. (453 aa)
	ccnb3	Cyclin B3; Belongs to the cyclin family. (431 aa)
	ENSACLP00000035671	Cell division cycle 20 homolog. (492 aa)
	cntd2	Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (406 aa)
	ENSACLP00000038411	Cell division cycle 20 homolog. (361 aa)
	ccnb1	Cyclin B1; Belongs to the cyclin family. (399 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000002506	ENSACLP00000003678	ENSACLP00000002506	ENSACLP00000003678	Uncharacterized protein.	TPX2 microtubule nucleation factor.	0.889
ENSACLP00000002506	ENSACLP00000006245	ENSACLP00000002506	ENSACLP00000006245	Uncharacterized protein.	Protein kinase domain-containing protein.	0.720
ENSACLP00000002506	ENSACLP00000007272	ENSACLP00000002506	ENSACLP00000007272	Uncharacterized protein.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.720
ENSACLP00000002506	ENSACLP00000035671	ENSACLP00000002506	ENSACLP00000035671	Uncharacterized protein.	Cell division cycle 20 homolog.	0.994
ENSACLP00000002506	ENSACLP00000038411	ENSACLP00000002506	ENSACLP00000038411	Uncharacterized protein.	Cell division cycle 20 homolog.	0.994
ENSACLP00000002506	LOC113008948	ENSACLP00000002506	ENSACLP00000005628	Uncharacterized protein.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.873
ENSACLP00000002506	LOC113009944	ENSACLP00000002506	ENSACLP00000020143	Uncharacterized protein.	Fizzy/cell division cycle 20 related 1b.	0.965
ENSACLP00000002506	LOC113013372	ENSACLP00000002506	ENSACLP00000007593	Uncharacterized protein.	Baculoviral IAP repeat containing 5b.	0.865
ENSACLP00000002506	LOC113028579	ENSACLP00000002506	ENSACLP00000021317	Uncharacterized protein.	Baculoviral IAP repeat containing 5a.	0.938
ENSACLP00000002506	LOC113031225	ENSACLP00000002506	ENSACLP00000019195	Uncharacterized protein.	Cyclin A2; Belongs to the cyclin family.	0.868
ENSACLP00000002506	LOC113035402	ENSACLP00000002506	ENSACLP00000002887	Uncharacterized protein.	Cyclin B2; Belongs to the cyclin family.	0.864
ENSACLP00000002506	PLK1	ENSACLP00000002506	ENSACLP00000006294	Uncharacterized protein.	Serine/threonine-protein kinase PLK.	0.795
ENSACLP00000002506	aurka	ENSACLP00000002506	ENSACLP00000028884	Uncharacterized protein.	Aurora kinase A; Belongs to the protein kinase superfamily.	0.873
ENSACLP00000002506	ccnb1	ENSACLP00000002506	ENSACLP00000040856	Uncharacterized protein.	Cyclin B1; Belongs to the cyclin family.	0.894
ENSACLP00000002506	ccnb3	ENSACLP00000002506	ENSACLP00000030436	Uncharacterized protein.	Cyclin B3; Belongs to the cyclin family.	0.737
ENSACLP00000002506	cdca8	ENSACLP00000002506	ENSACLP00000007842	Uncharacterized protein.	Cell division cycle associated 8.	0.868
ENSACLP00000002506	cntd2	ENSACLP00000002506	ENSACLP00000035747	Uncharacterized protein.	Cyclin N-terminal domain containing 2; Belongs to the cyclin family.	0.864
ENSACLP00000002506	espl1	ENSACLP00000002506	ENSACLP00000000991	Uncharacterized protein.	Extra spindle pole bodies like 1, separase.	0.997
ENSACLP00000002506	plk2	ENSACLP00000002506	ENSACLP00000024227	Uncharacterized protein.	Serine/threonine-protein kinase PLK.	0.795
ENSACLP00000003678	ENSACLP00000002506	ENSACLP00000003678	ENSACLP00000002506	TPX2 microtubule nucleation factor.	Uncharacterized protein.	0.889