STRINGSTRING
LOC113016116 LOC113016116 plcg2 plcg2 LOC113024435 LOC113024435 LOC113030276 LOC113030276 sos2 sos2 irs2 irs2 ENSACLP00000006489 ENSACLP00000006489 LOC113033441 LOC113033441 LOC113018742 LOC113018742 SHC3 SHC3 ENSACLP00000011022 ENSACLP00000011022 ENSACLP00000011894 ENSACLP00000011894 ENSACLP00000013425 ENSACLP00000013425 ENSACLP00000014200 ENSACLP00000014200 LOC113010568 LOC113010568 LOC113011234 LOC113011234 LOC113018242 LOC113018242 pik3cb pik3cb LOC113010606 LOC113010606 ENSACLP00000019486 ENSACLP00000019486 LOC113031192 LOC113031192 LOC113035041 LOC113035041 kdr kdr LOC113027917 LOC113027917 LOC113013184 LOC113013184 LOC113029559 LOC113029559 grb2 grb2 shc1 shc1 ENSACLP00000028350 ENSACLP00000028350 LOC113026105 LOC113026105 LOC113019078 LOC113019078 LOC113020258 LOC113020258 LOC113015984 LOC113015984 igf1r igf1r LOC113009053 LOC113009053 LOC113009003 LOC113009003 gab2 gab2 ENSACLP00000034020 ENSACLP00000034020 ENSACLP00000034346 ENSACLP00000034346 ptpn6 ptpn6 ptpn11 ptpn11 gab1 gab1 pik3cd pik3cd pik3r1 pik3r1 LOC113015828 LOC113015828
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC113016116SHC (Src homology 2 domain containing) transforming protein 2. (726 aa)
plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1249 aa)
LOC113024435GRB2 related adaptor protein b. (261 aa)
LOC113030276Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1025 aa)
sos2Son of sevenless homolog 2 (Drosophila). (1331 aa)
irs2Insulin receptor substrate 2b. (1103 aa)
ENSACLP00000006489Son of sevenless homolog 1 (Drosophila). (1443 aa)
LOC113033441Uncharacterized protein. (717 aa)
LOC113018742Si:ch73-335l21.1. (1295 aa)
SHC3SHC adaptor protein 3. (661 aa)
ENSACLP00000011022Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (694 aa)
ENSACLP00000011894GRB2 related adaptor protein 2b. (227 aa)
ENSACLP00000013425Tyrosine-protein phosphatase non-receptor type. (386 aa)
ENSACLP00000014200Receptor protein-tyrosine kinase. (1407 aa)
LOC113010568Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC113011234Tyrosine-protein kinase receptor. (1365 aa)
LOC113018242PH domain-containing protein. (781 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1078 aa)
LOC113010606Phosphoinositide-3-kinase, regulatory subunit 3a (gamma). (467 aa)
ENSACLP00000019486Protein tyrosine phosphatase non-receptor type 11b. (547 aa)
LOC113031192Si:ch211-284e13.4. (1172 aa)
LOC113035041Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (464 aa)
kdrKinase insert domain receptor (a type III receptor tyrosine kinase). (1356 aa)
LOC113027917Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (411 aa)
LOC113013184Tyrosine-protein kinase. (552 aa)
LOC113029559Receptor protein-tyrosine kinase. (1175 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (600 aa)
ENSACLP00000028350Tyrosine-protein kinase receptor. (1438 aa)
LOC113026105Tyrosine-protein kinase receptor. (1417 aa)
LOC113019078Insulin receptor substrate 4a. (1404 aa)
LOC113020258Uncharacterized protein. (220 aa)
LOC113015984Tyrosine-protein kinase receptor. (1401 aa)
igf1rTyrosine-protein kinase receptor. (1418 aa)
LOC113009053Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (698 aa)
LOC1130090031-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1312 aa)
gab2GRB2-associated binding protein 2. (654 aa)
ENSACLP00000034020Uncharacterized protein. (400 aa)
ENSACLP00000034346Uncharacterized protein. (258 aa)
ptpn6Protein tyrosine phosphatase non-receptor type 6. (583 aa)
ptpn11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (603 aa)
gab1GRB2-associated binding protein 1. (746 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (729 aa)
LOC113015828Insulin receptor substrate 2a. (1052 aa)
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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