22 items (Astatotilapia calliptera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	irs2	Insulin receptor substrate 2b. (1103 aa)
	LOC113033441	Uncharacterized protein. (717 aa)
	LOC113018742	Si:ch73-335l21.1. (1295 aa)
	ENSACLP00000011022	Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (694 aa)
	ENSACLP00000013425	Tyrosine-protein phosphatase non-receptor type. (386 aa)
	LOC113010568	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC113011234	Tyrosine-protein kinase receptor. (1365 aa)
	pik3cb	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1078 aa)
	LOC113010606	Phosphoinositide-3-kinase, regulatory subunit 3a (gamma). (467 aa)
	LOC113031192	Si:ch211-284e13.4. (1172 aa)
	LOC113035041	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (464 aa)
	LOC113027917	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (411 aa)
	LOC113013184	Tyrosine-protein kinase. (552 aa)
	LOC113026105	Tyrosine-protein kinase receptor. (1417 aa)
	LOC113019078	Insulin receptor substrate 4a. (1404 aa)
	LOC113015984	Tyrosine-protein kinase receptor. (1401 aa)
	igf1r	Tyrosine-protein kinase receptor. (1418 aa)
	LOC113009053	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (698 aa)
	ENSACLP00000034020	Uncharacterized protein. (400 aa)
	ENSACLP00000034346	Uncharacterized protein. (258 aa)
	pik3cd	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa)
	LOC113015828	Insulin receptor substrate 2a. (1052 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000011022	ENSACLP00000034020	ENSACLP00000011022	ENSACLP00000034020	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Uncharacterized protein.	0.816
ENSACLP00000011022	LOC113010568	ENSACLP00000011022	ENSACLP00000015873	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.930
ENSACLP00000011022	LOC113010606	ENSACLP00000011022	ENSACLP00000018537	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Phosphoinositide-3-kinase, regulatory subunit 3a (gamma).	0.818
ENSACLP00000011022	LOC113011234	ENSACLP00000011022	ENSACLP00000016530	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Tyrosine-protein kinase receptor.	0.778
ENSACLP00000011022	LOC113013184	ENSACLP00000011022	ENSACLP00000025858	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Tyrosine-protein kinase.	0.928
ENSACLP00000011022	LOC113015828	ENSACLP00000011022	ENSACLP00000040134	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Insulin receptor substrate 2a.	0.929
ENSACLP00000011022	LOC113015984	ENSACLP00000011022	ENSACLP00000031503	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Tyrosine-protein kinase receptor.	0.778
ENSACLP00000011022	LOC113018742	ENSACLP00000011022	ENSACLP00000009140	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Si:ch73-335l21.1.	0.929
ENSACLP00000011022	LOC113019078	ENSACLP00000011022	ENSACLP00000028747	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Insulin receptor substrate 4a.	0.929
ENSACLP00000011022	LOC113026105	ENSACLP00000011022	ENSACLP00000028600	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Tyrosine-protein kinase receptor.	0.853
ENSACLP00000011022	LOC113027917	ENSACLP00000011022	ENSACLP00000024033	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.882
ENSACLP00000011022	LOC113031192	ENSACLP00000011022	ENSACLP00000020671	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Si:ch211-284e13.4.	0.929
ENSACLP00000011022	LOC113033441	ENSACLP00000011022	ENSACLP00000009076	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Uncharacterized protein.	0.818
ENSACLP00000011022	LOC113035041	ENSACLP00000011022	ENSACLP00000022923	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.890
ENSACLP00000011022	igf1r	ENSACLP00000011022	ENSACLP00000032394	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Tyrosine-protein kinase receptor.	0.853
ENSACLP00000011022	irs2	ENSACLP00000011022	ENSACLP00000006002	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Insulin receptor substrate 2b.	0.928
ENSACLP00000011022	pik3cb	ENSACLP00000011022	ENSACLP00000018358	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.930
ENSACLP00000011022	pik3cd	ENSACLP00000011022	ENSACLP00000038522	Phosphoinositide-3-kinase, regulatory subunit 2 (beta).	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.930
ENSACLP00000013425	ENSACLP00000034346	ENSACLP00000013425	ENSACLP00000034346	Tyrosine-protein phosphatase non-receptor type.	Uncharacterized protein.	0.635
ENSACLP00000013425	LOC113010568	ENSACLP00000013425	ENSACLP00000015873	Tyrosine-protein phosphatase non-receptor type.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.428