(28 nodes) DNA synthesis involved in DNA repair network (Astatotilapia calliptera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSACLP00000000986	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2036 aa)
	rev1	REV1 DNA directed polymerase. (1390 aa)
	vcp	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (443 aa)
	polk	Polymerase (DNA directed) kappa. (875 aa)
	ENSACLP00000010605	DNA polymerase. (1128 aa)
	cdkn2d	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
	spata22	Uncharacterized protein. (398 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
	ENSACLP00000017593	Polymerase (DNA directed), delta 2, regulatory subunit. (482 aa)
	ENSACLP00000017846	Poly [ADP-ribose] polymerase. (612 aa)
	ENSACLP00000020901	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (499 aa)
	polh	Polymerase (DNA directed), eta. (738 aa)
	poldip2	Polymerase (DNA-directed), delta interacting protein 2. (377 aa)
	zbtb1	Zinc finger and BTB domain containing 1. (668 aa)
	pold4	Si:dkey-28b4.7. (121 aa)
	rev3l	REV3 like, DNA directed polymerase zeta catalytic subunit. (3016 aa)
	wrnip1	WRN helicase interacting protein 1. (603 aa)
	poli	Polymerase (DNA directed) iota. (720 aa)
	primpol	Primase and polymerase (DNA-directed). (548 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (715 aa)
	ENSACLP00000033415	PCNA clamp associated factor. (94 aa)
	ENSACLP00000033936	DNA polymerase. (1326 aa)
	dtl	Denticleless E3 ubiquitin protein ligase homolog (Drosophila). (661 aa)
	ENSACLP00000034749	WD_REPEATS_REGION domain-containing protein. (132 aa)
	ENSACLP00000035605	Zgc:136908; Belongs to the AAA ATPase family. (721 aa)
	hrob	Si:dkey-260c8.8. (614 aa)
	ENSACLP00000040960	SprT-like N-terminal domain. (433 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000000986	ENSACLP00000010605	ENSACLP00000000986	ENSACLP00000010605	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	DNA polymerase.	0.994
ENSACLP00000000986	ENSACLP00000017593	ENSACLP00000000986	ENSACLP00000017593	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	Polymerase (DNA directed), delta 2, regulatory subunit.	0.992
ENSACLP00000000986	ENSACLP00000020901	ENSACLP00000000986	ENSACLP00000020901	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.999
ENSACLP00000000986	ENSACLP00000033415	ENSACLP00000000986	ENSACLP00000033415	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	PCNA clamp associated factor.	0.679
ENSACLP00000000986	ENSACLP00000033936	ENSACLP00000000986	ENSACLP00000033936	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	DNA polymerase.	0.995
ENSACLP00000000986	ENSACLP00000034749	ENSACLP00000000986	ENSACLP00000034749	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	WD_REPEATS_REGION domain-containing protein.	0.859
ENSACLP00000000986	ENSACLP00000040960	ENSACLP00000000986	ENSACLP00000040960	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	SprT-like N-terminal domain.	0.422
ENSACLP00000000986	dtl	ENSACLP00000000986	ENSACLP00000034658	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	0.859
ENSACLP00000000986	pcna	ENSACLP00000000986	ENSACLP00000017122	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.990
ENSACLP00000000986	pold3	ENSACLP00000000986	ENSACLP00000004188	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	Polymerase (DNA-directed), delta 3, accessory subunit.	0.901
ENSACLP00000000986	pold4	ENSACLP00000000986	ENSACLP00000026976	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	Si:dkey-28b4.7.	0.876
ENSACLP00000000986	polh	ENSACLP00000000986	ENSACLP00000021778	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	Polymerase (DNA directed), eta.	0.934
ENSACLP00000000986	poli	ENSACLP00000000986	ENSACLP00000030261	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	Polymerase (DNA directed) iota.	0.916
ENSACLP00000000986	polk	ENSACLP00000000986	ENSACLP00000006479	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	Polymerase (DNA directed) kappa.	0.913
ENSACLP00000000986	rev1	ENSACLP00000000986	ENSACLP00000001942	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	REV1 DNA directed polymerase.	0.923
ENSACLP00000000986	rev3l	ENSACLP00000000986	ENSACLP00000027681	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.905
ENSACLP00000000986	wrnip1	ENSACLP00000000986	ENSACLP00000030034	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	WRN helicase interacting protein 1.	0.422
ENSACLP00000010605	ENSACLP00000000986	ENSACLP00000010605	ENSACLP00000000986	DNA polymerase.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.994
ENSACLP00000010605	ENSACLP00000017593	ENSACLP00000010605	ENSACLP00000017593	DNA polymerase.	Polymerase (DNA directed), delta 2, regulatory subunit.	0.999
ENSACLP00000010605	ENSACLP00000020901	ENSACLP00000010605	ENSACLP00000020901	DNA polymerase.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.989