(14 nodes) Blood vessel remodeling network (Astatotilapia calliptera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSACLP00000029012	R-spondin 3. (268 aa)
	LOC113029596	Zgc:153993. (274 aa)
	atg5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	bax	Uncharacterized protein. (205 aa)
	ENSACLP00000006475	Uncharacterized protein. (165 aa)
	LOC113007501	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1199 aa)
	ENSACLP00000016764	Uncharacterized protein. (679 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (471 aa)
	crb1	Crumbs cell polarity complex component 1. (1316 aa)
	LOC113033870	Crumbs cell polarity complex component 2b. (1467 aa)
	sema3c	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (765 aa)
	LOC113025297	Uncharacterized protein. (1466 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1067 aa)
	ednra	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (442 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDNRA	ednra	ENSACLP00000017504	ENSACLP00000037935	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	0.850
ENSACLP00000006475	LOC113029596	ENSACLP00000006475	ENSACLP00000000007	Uncharacterized protein.	Zgc:153993.	0.967
LOC113007501	bmpr2	ENSACLP00000015194	ENSACLP00000037110	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.818
LOC113029596	ENSACLP00000006475	ENSACLP00000000007	ENSACLP00000006475	Zgc:153993.	Uncharacterized protein.	0.967
LOC113029596	bax	ENSACLP00000000007	ENSACLP00000006340	Zgc:153993.	Uncharacterized protein.	0.969
bax	LOC113029596	ENSACLP00000006340	ENSACLP00000000007	Uncharacterized protein.	Zgc:153993.	0.969
bmpr2	LOC113007501	ENSACLP00000037110	ENSACLP00000015194	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.818
ednra	EDNRA	ENSACLP00000037935	ENSACLP00000017504	Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.850