(9 nodes) Positive regulation of peptidyl-threonine phosphorylation network (Astatotilapia calliptera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rptor	Regulatory associated protein of MTOR, complex 1. (1350 aa)
	LOC113014387	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (438 aa)
	LOC113036502	Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
	LOC113024166	Ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
	stox1	Storkhead box 1. (1090 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (576 aa)
	LOC113032794	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
	LOC113036628	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (425 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC113014387	LOC113036502	ENSACLP00000031037	ENSACLP00000028286	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.424
LOC113014387	rptor	ENSACLP00000031037	ENSACLP00000015112	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	Regulatory associated protein of MTOR, complex 1.	0.525
LOC113024166	LOC113036628	ENSACLP00000023097	ENSACLP00000014143	Ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.	0.829
LOC113032794	LOC113036502	ENSACLP00000038681	ENSACLP00000028286	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.424
LOC113032794	rptor	ENSACLP00000038681	ENSACLP00000015112	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	Regulatory associated protein of MTOR, complex 1.	0.525
LOC113036502	LOC113014387	ENSACLP00000028286	ENSACLP00000031037	Transforming growth factor beta; Belongs to the TGF-beta family.	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	0.424
LOC113036502	LOC113032794	ENSACLP00000028286	ENSACLP00000038681	Transforming growth factor beta; Belongs to the TGF-beta family.	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	0.424
LOC113036502	gsk3b	ENSACLP00000028286	ENSACLP00000006469	Transforming growth factor beta; Belongs to the TGF-beta family.	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.	0.424
LOC113036628	LOC113024166	ENSACLP00000014143	ENSACLP00000023097	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	0.829
gsk3b	LOC113036502	ENSACLP00000006469	ENSACLP00000028286	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.424
gsk3b	rptor	ENSACLP00000006469	ENSACLP00000015112	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.	Regulatory associated protein of MTOR, complex 1.	0.525
ripk2	rptor	ENSACLP00000015326	ENSACLP00000015112	Receptor-interacting serine-threonine kinase 2.	Regulatory associated protein of MTOR, complex 1.	0.428
rptor	LOC113014387	ENSACLP00000015112	ENSACLP00000031037	Regulatory associated protein of MTOR, complex 1.	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	0.525
rptor	LOC113032794	ENSACLP00000015112	ENSACLP00000038681	Regulatory associated protein of MTOR, complex 1.	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	0.525
rptor	gsk3b	ENSACLP00000015112	ENSACLP00000006469	Regulatory associated protein of MTOR, complex 1.	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.	0.525
rptor	ripk2	ENSACLP00000015112	ENSACLP00000015326	Regulatory associated protein of MTOR, complex 1.	Receptor-interacting serine-threonine kinase 2.	0.428