(52 nodes) Positive regulation of mitochondrion organization network (Astatotilapia calliptera)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSACLP00000040197	CARD domain-containing protein. (91 aa)
	LOC113029596	Zgc:153993. (274 aa)
	LOC113025578	Zgc:73226. (181 aa)
	ppargc1a	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (1275 aa)
	bmf	Uncharacterized protein. (170 aa)
	LOC113024462	Mitochondrial elongation factor 2. (466 aa)
	ENSACLP00000005288	Vacuolar protein sorting 13 homolog D. (4306 aa)
	bax	Uncharacterized protein. (205 aa)
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (425 aa)
	ENSACLP00000006475	Uncharacterized protein. (165 aa)
	pdcd5	Programmed cell death 5. (132 aa)
	ENSACLP00000009275	Uncharacterized protein. (188 aa)
	ENSACLP00000010509	Uncharacterized protein. (194 aa)
	pla2g6	Phospholipase A2, group VI (cytosolic, calcium-independent). (820 aa)
	zdhhc6	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (412 aa)
	prkn	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (456 aa)
	ralbp1	RalA binding protein 1. (674 aa)
	ENSACLP00000012232	F-box protein 7. (489 aa)
	MFF	Miff domain-containing protein. (288 aa)
	ENSACLP00000014595	MLLT11 transcription factor 7 cofactor. (97 aa)
	vps35	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (798 aa)
	ENSACLP00000016489	CARD domain-containing protein. (93 aa)
	ENSACLP00000016500	CARD domain-containing protein. (101 aa)
	ENSACLP00000016507	CARD domain-containing protein. (95 aa)
	LOC113032849	CARD domain-containing protein. (174 aa)
	mief1	Mitochondrial elongation factor 1. (490 aa)
	ENSACLP00000016947	CARD domain-containing protein. (95 aa)
	ENSACLP00000017063	Uncharacterized protein. (198 aa)
	ENSACLP00000017703	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (386 aa)
	LOC113012128	DDHD domain containing 1a. (808 aa)
	ENSACLP00000021832	Huntingtin. (2558 aa)
	ssbp1	Single-stranded DNA binding protein 1. (147 aa)
	bnip3	BCL2 interacting protein 3. (189 aa)
	LOC113017320	Uncharacterized protein. (207 aa)
	ENSACLP00000027937	Cell death inducing DFFA like effector c. (222 aa)
	mul1	Mitochondrial E3 ubiquitin protein ligase 1b. (352 aa)
	pink1	PTEN induced kinase 1. (574 aa)
	pgam5	PGAM family member 5, serine/threonine protein phosphatase, mitochondrial. (300 aa)
	LOC113006665	DDHD domain containing 1b. (851 aa)
	LOC113014387	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (438 aa)
	bad	BCL2 associated agonist of cell death b. (158 aa)
	ambra1	Autophagy/beclin-1 regulator 1b. (1358 aa)
	LOC113009045	Decorin; May affect the rate of fibrils formation. (358 aa)
	ENSACLP00000038389	Uncharacterized protein. (198 aa)
	ENSACLP00000038429	Uncharacterized protein. (207 aa)
	LOC113032090	Uncharacterized protein. (323 aa)
	ENSACLP00000038493	Uncharacterized protein. (210 aa)
	LOC113032794	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
	stoml2	Stomatin (EPB72)-like 2. (356 aa)
	fam162a	Family with sequence similarity 162 member A. (159 aa)
	ENSACLP00000040066	Uncharacterized protein. (472 aa)
	LOC113030608	CARD domain-containing protein. (199 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000006475	LOC113025578	ENSACLP00000006475	ENSACLP00000000843	Uncharacterized protein.	Zgc:73226.	0.617
ENSACLP00000006475	LOC113029596	ENSACLP00000006475	ENSACLP00000000007	Uncharacterized protein.	Zgc:153993.	0.967
ENSACLP00000006475	bad	ENSACLP00000006475	ENSACLP00000031622	Uncharacterized protein.	BCL2 associated agonist of cell death b.	0.847
ENSACLP00000006475	bmf	ENSACLP00000006475	ENSACLP00000003496	Uncharacterized protein.	Uncharacterized protein.	0.641
ENSACLP00000006475	bnip3	ENSACLP00000006475	ENSACLP00000024118	Uncharacterized protein.	BCL2 interacting protein 3.	0.617
ENSACLP00000006475	pgam5	ENSACLP00000006475	ENSACLP00000029438	Uncharacterized protein.	PGAM family member 5, serine/threonine protein phosphatase, mitochondrial.	0.586
ENSACLP00000006475	pink1	ENSACLP00000006475	ENSACLP00000029037	Uncharacterized protein.	PTEN induced kinase 1.	0.691
ENSACLP00000006475	prkn	ENSACLP00000006475	ENSACLP00000011571	Uncharacterized protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.887
ENSACLP00000012232	pink1	ENSACLP00000012232	ENSACLP00000029037	F-box protein 7.	PTEN induced kinase 1.	0.704
ENSACLP00000012232	pla2g6	ENSACLP00000012232	ENSACLP00000011094	F-box protein 7.	Phospholipase A2, group VI (cytosolic, calcium-independent).	0.536
ENSACLP00000012232	prkn	ENSACLP00000012232	ENSACLP00000011571	F-box protein 7.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.630
ENSACLP00000012232	vps35	ENSACLP00000012232	ENSACLP00000015525	F-box protein 7.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.573
ENSACLP00000017063	LOC113032849	ENSACLP00000017063	ENSACLP00000016512	Uncharacterized protein.	CARD domain-containing protein.	0.556
ENSACLP00000021832	ppargc1a	ENSACLP00000021832	ENSACLP00000001514	Huntingtin.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.922
ENSACLP00000021832	prkn	ENSACLP00000021832	ENSACLP00000011571	Huntingtin.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.685
LOC113014387	bad	ENSACLP00000031037	ENSACLP00000031622	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	BCL2 associated agonist of cell death b.	0.485
LOC113014387	prkn	ENSACLP00000031037	ENSACLP00000011571	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.539
LOC113024462	MFF	ENSACLP00000004064	ENSACLP00000013870	Mitochondrial elongation factor 2.	Miff domain-containing protein.	0.577
LOC113025578	ENSACLP00000006475	ENSACLP00000000843	ENSACLP00000006475	Zgc:73226.	Uncharacterized protein.	0.617
LOC113025578	LOC113029596	ENSACLP00000000843	ENSACLP00000000007	Zgc:73226.	Zgc:153993.	0.617