(123 nodes) Negative regulation of cellular catabolic process network (Astatotilapia calliptera)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	usp14	Ubiquitin carboxyl-terminal hydrolase. (491 aa)
	igf2bp3	Insulin-like growth factor 2 mRNA binding protein 3. (588 aa)
	tirap	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein. (291 aa)
	dazl	Deleted in azoospermia-like. (217 aa)
	LOC113027635	Plakophilin 3b. (768 aa)
	ENSACLP00000001630	Uncharacterized protein. (60 aa)
	lepr	Leptin receptor. (1181 aa)
	foxk1	Forkhead box K1. (671 aa)
	bmf	Uncharacterized protein. (170 aa)
	fez1	Fasciculation and elongation protein zeta 1 (zygin I). (403 aa)
	LOC113016001	RRM domain-containing protein. (334 aa)
	meioc	Uncharacterized protein. (775 aa)
	LOC113021333	Insulin-like growth factor 2 mRNA binding protein 1. (601 aa)
	tmem39b	Transmembrane protein 39B. (489 aa)
	tent2	Terminal nucleotidyltransferase 2. (486 aa)
	angel2	Angel homolog 2 (Drosophila). (702 aa)
	LOC113032764	RNA binding motif protein 24b. (235 aa)
	etfbkmt	Electron transfer flavoprotein subunit beta lysine methyltransferase. (258 aa)
	phf23	PHD finger protein 23b. (320 aa)
	ENSACLP00000006439	Nuclear receptor binding protein 2b. (467 aa)
	LOC113023368	Carboxypeptidase; Belongs to the peptidase S10 family. (463 aa)
	ogt	O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1. (1038 aa)
	il10	Interleukin 10. (182 aa)
	mapkapk2	MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (389 aa)
	ENSACLP00000009186	Nuclear protein 1a. (73 aa)
	dnd1	DND microRNA-mediated repression inhibitor 1. (390 aa)
	gipc2	GIPC PDZ domain containing family, member 2. (329 aa)
	ENSACLP00000010567	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (474 aa)
	LOC113033485	Leucine zipper, putative tumor suppressor 1. (671 aa)
	ENSACLP00000011345	Suppressor of fused homolog. (472 aa)
	ENSACLP00000011551	QKI, KH domain containing, RNA binding b. (343 aa)
	trdmt1	tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (382 aa)
	ENSACLP00000011634	Uncharacterized protein. (382 aa)
	LOC113006551	Si:ch211-57i17.1. (396 aa)
	ENSACLP00000012749	Uncharacterized protein. (360 aa)
	nbas	Neuroblastoma amplified sequence. (2372 aa)
	TIMP3	TIMP metallopeptidase inhibitor 3. (284 aa)
	LOC113012021	ELAV-like protein; Belongs to the RRM elav family. (343 aa)
	LOC113014871	Terminal nucleotidyltransferase 5Bb. (393 aa)
	clec16a	C-type lectin domain containing 16A. (1133 aa)
	usp7	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1112 aa)
	ENSACLP00000015308	Terminal nucleotidyltransferase 5D. (389 aa)
	LOC113031594	BCL2 associated athanogene 6. (1227 aa)
	EIF4ENIF1	Eukaryotic translation initiation factor 4E nuclear import factor 1. (955 aa)
	bag5	BCL2 associated athanogene 5. (514 aa)
	ENSACLP00000015815	Si:ch73-147o17.1. (103 aa)
	ENSACLP00000015913	Nocturnin a. (371 aa)
	ENSACLP00000016234	SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3600 aa)
	PKP3	Plakophilin 3. (827 aa)
	LOC113012209	SEFIR domain-containing protein. (437 aa)
	mtmr9	Myotubularin related protein 9. (564 aa)
	nop53	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (464 aa)
	sirt2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (382 aa)
	timp4	TIMP metallopeptidase inhibitor 4, tandem duplicate 2. (224 aa)
	TIMP2	TIMP metallopeptidase inhibitor 2. (220 aa)
	tsc1	TSC complex subunit 1b. (1277 aa)
	fhit	Bis(5'-adenosyl)-triphosphatase. (149 aa)
	htr2b	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled. (478 aa)
	rubcn	Rubicon autophagy regulator. (1018 aa)
	gipc3	GIPC PDZ domain containing family, member 3. (334 aa)
	vip	Vasoactive intestinal peptide. (150 aa)
	LOC113020696	TIMP metallopeptidase inhibitor 2b. (222 aa)
	uchl5	Ubiquitin carboxyl-terminal hydrolase. (359 aa)
	nrde2	NRDE-2, necessary for RNA interference, domain containing. (1186 aa)
	LOC113027476	Uncharacterized protein. (161 aa)
	FOXK2	Forkhead box K2. (615 aa)
	TENT5A	Terminal nucleotidyltransferase 5A. (401 aa)
	hsp90ab1	Heat shock protein 90, alpha (cytosolic), class B member 1. (727 aa)
	LOC113033866	Uncharacterized protein. (1206 aa)
	ENSACLP00000035182	Leucine-rich pentatricopeptide repeat containing. (1308 aa)
	ybx1	Y box binding protein 1. (321 aa)
	ENSACLP00000033361	GIPC PDZ domain containing family, member 1. (351 aa)
	bcl2	BCL2 apoptosis regulator b. (228 aa)
	dhx9	DEAH (Asp-Glu-Ala-His) box helicase 9. (1271 aa)
	ENSACLP00000031455	Leucine-rich repeat kinase 2. (2416 aa)
	tmem39a	Transmembrane protein 39A. (493 aa)
	ENSACLP00000030835	TSC complex subunit 2. (1705 aa)
	dap	Death-associated protein. (104 aa)
	LOC113020236	Forkhead box K2. (607 aa)
	sorl1	Sortilin-related receptor, L(DLR class) A repeats containing. (2262 aa)
	ENSACLP00000029064	Zgc:154055. (513 aa)
	pink1	PTEN induced kinase 1. (574 aa)
	LOC113016105	ELAV-like protein; Belongs to the RRM elav family. (370 aa)
	RBM38	RNA binding motif protein 38. (244 aa)
	wdr6	WD repeat domain 6. (1364 aa)
	LOC113015754	TRAF3 interacting protein 2-like. (440 aa)
	zcchc17	Zinc finger, CCHC domain containing 17. (248 aa)
	cptp	Ceramide-1-phosphate transfer protein. (218 aa)
	traf3ip2	SEFIR domain-containing protein. (419 aa)
	fus	FUS RNA binding protein. (548 aa)
	tspo	Translocator protein. (161 aa)
	dffb	DNA fragmentation factor, beta polypeptide (caspase-activated DNase). (343 aa)
	tent4b	Terminal nucleotidyltransferase 4B. (669 aa)
	qrich2	Uncharacterized protein. (1005 aa)
	ENSACLP00000025638	Apobec1 complementation factor. (585 aa)
	LOC113029594	BH4_2 domain-containing protein. (198 aa)
	scfd1	Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (631 aa)
	ENSACLP00000025109	Uncharacterized protein. (413 aa)
	LOC113014726	RNA binding motif protein 24a. (261 aa)
	ENSACLP00000024780	Terminal nucleotidyltransferase 5C. (380 aa)
	ENSACLP00000024753	Uncharacterized protein. (82 aa)
	LOC113032634	Uncharacterized protein. (821 aa)
	phax	Phosphorylated adaptor for RNA export. (409 aa)
	ENSACLP00000018362	Serine/threonine-protein kinase TOR. (2384 aa)
	tent5b	Terminal nucleotidyltransferase 5ba. (392 aa)
	styx	Serine/threonine/tyrosine interacting protein. (259 aa)
	LOC113032701	Si:dkey-288i20.2. (398 aa)
	dapl1	Death associated protein 1b. (116 aa)
	dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1064 aa)
	nsun2	NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (773 aa)
	e2f1	E2F transcription factor 1. (454 aa)
	ENSACLP00000021240	Terminal nucleotidyltransferase 4A. (525 aa)
	camlg	Calcium modulating ligand. (283 aa)
	ctsa	Carboxypeptidase; Belongs to the peptidase S10 family. (473 aa)
	n4bp1	Nedd4 binding protein 1. (979 aa)
	gdnf	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (257 aa)
	LOC113014194	BCL2 associated athanogene 6, like. (1200 aa)
	igf2bp2	Insulin-like growth factor 2 mRNA binding protein 2a. (611 aa)
	ENSACLP00000023026	Dyskeratosis congenita 1, dyskerin. (491 aa)
	poldip2	Polymerase (DNA-directed), delta interacting protein 2. (377 aa)
	ubxn1	UBX domain protein 1. (314 aa)
	rbm46	RNA binding motif protein 46. (574 aa)
	klhl22	Kelch-like family member 22. (638 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF4ENIF1	uchl5	ENSACLP00000015608	ENSACLP00000037285	Eukaryotic translation initiation factor 4E nuclear import factor 1.	Ubiquitin carboxyl-terminal hydrolase.	0.416
EIF4ENIF1	usp7	ENSACLP00000015608	ENSACLP00000015131	Eukaryotic translation initiation factor 4E nuclear import factor 1.	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.	0.402
ENSACLP00000001630	ENSACLP00000016234	ENSACLP00000001630	ENSACLP00000016234	Uncharacterized protein.	SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.	0.756
ENSACLP00000001630	ENSACLP00000018362	ENSACLP00000001630	ENSACLP00000018362	Uncharacterized protein.	Serine/threonine-protein kinase TOR.	0.906
ENSACLP00000001630	ENSACLP00000030835	ENSACLP00000001630	ENSACLP00000030835	Uncharacterized protein.	TSC complex subunit 2.	0.925
ENSACLP00000001630	LOC113012209	ENSACLP00000001630	ENSACLP00000017108	Uncharacterized protein.	SEFIR domain-containing protein.	0.478
ENSACLP00000001630	LOC113015754	ENSACLP00000001630	ENSACLP00000028380	Uncharacterized protein.	TRAF3 interacting protein 2-like.	0.478
ENSACLP00000001630	pink1	ENSACLP00000001630	ENSACLP00000029037	Uncharacterized protein.	PTEN induced kinase 1.	0.600
ENSACLP00000001630	traf3ip2	ENSACLP00000001630	ENSACLP00000027754	Uncharacterized protein.	SEFIR domain-containing protein.	0.478
ENSACLP00000010567	ENSACLP00000025638	ENSACLP00000010567	ENSACLP00000025638	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Apobec1 complementation factor.	0.636
ENSACLP00000010567	LOC113012021	ENSACLP00000010567	ENSACLP00000013632	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	ELAV-like protein; Belongs to the RRM elav family.	0.526
ENSACLP00000010567	LOC113016001	ENSACLP00000010567	ENSACLP00000003685	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	RRM domain-containing protein.	0.570
ENSACLP00000010567	LOC113016105	ENSACLP00000010567	ENSACLP00000028797	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	ELAV-like protein; Belongs to the RRM elav family.	0.604
ENSACLP00000010567	dazl	ENSACLP00000010567	ENSACLP00000000750	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Deleted in azoospermia-like.	0.432
ENSACLP00000010567	dhx9	ENSACLP00000010567	ENSACLP00000032879	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	DEAH (Asp-Glu-Ala-His) box helicase 9.	0.587
ENSACLP00000010567	dnd1	ENSACLP00000010567	ENSACLP00000009355	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	DND microRNA-mediated repression inhibitor 1.	0.636
ENSACLP00000010567	fus	ENSACLP00000010567	ENSACLP00000027381	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	FUS RNA binding protein.	0.852
ENSACLP00000010567	rbm46	ENSACLP00000010567	ENSACLP00000023731	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	RNA binding motif protein 46.	0.636
ENSACLP00000010567	ybx1	ENSACLP00000010567	ENSACLP00000033494	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Y box binding protein 1.	0.691
ENSACLP00000011551	LOC113012209	ENSACLP00000011551	ENSACLP00000017108	QKI, KH domain containing, RNA binding b.	SEFIR domain-containing protein.	0.401