(22 nodes) Secretory granule organization network (Astatotilapia calliptera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113011157	Aquaporin 1a (Colton blood group), tandem duplicate 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
	LOC113011103	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (262 aa)
	tmf1	TATA element modulatory factor 1. (1153 aa)
	LOC113035690	Sorting nexin 19b. (981 aa)
	tbc1d20	TBC1 domain family, member 20. (397 aa)
	bloc1s3	Biogenesis of lysosomal organelles complex-1, subunit 3. (187 aa)
	knl1	Knl1_RWD_C domain-containing protein. (2010 aa)
	LOC113009301	Uncharacterized protein. (425 aa)
	LOC113030093	Uncharacterized protein. (282 aa)
	ENSACLP00000012122	Uncharacterized protein. (143 aa)
	LOC113031610	Uncharacterized protein. (350 aa)
	ENSACLP00000006506	Coiled-coil domain containing 136b. (406 aa)
	hps4	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (619 aa)
	LOC113036168	ArfGAP with FG repeats 1a. (634 aa)
	ENSACLP00000013929	ArfGAP with FG repeats 1b. (581 aa)
	VPS13B	Vacuolar protein sorting 13 homolog B. (3910 aa)
	ENSACLP00000017121	Uncharacterized protein. (125 aa)
	LOC113014360	Zgc:63863. (432 aa)
	serpine2	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (397 aa)
	LOC113030282	Sorting nexin 19a. (897 aa)
	LOC113014242	Dystrobrevin binding protein 1b. (272 aa)
	LOC113011158	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (256 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC113014242	bloc1s3	ENSACLP00000022538	ENSACLP00000032692	Dystrobrevin binding protein 1b.	Biogenesis of lysosomal organelles complex-1, subunit 3.	0.958
LOC113014242	hps4	ENSACLP00000022538	ENSACLP00000000479	Dystrobrevin binding protein 1b.	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.	0.534
LOC113031610	bloc1s3	ENSACLP00000006620	ENSACLP00000032692	Uncharacterized protein.	Biogenesis of lysosomal organelles complex-1, subunit 3.	0.788
bloc1s3	LOC113014242	ENSACLP00000032692	ENSACLP00000022538	Biogenesis of lysosomal organelles complex-1, subunit 3.	Dystrobrevin binding protein 1b.	0.958
bloc1s3	LOC113031610	ENSACLP00000032692	ENSACLP00000006620	Biogenesis of lysosomal organelles complex-1, subunit 3.	Uncharacterized protein.	0.788
bloc1s3	hps4	ENSACLP00000032692	ENSACLP00000000479	Biogenesis of lysosomal organelles complex-1, subunit 3.	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.	0.536
hps4	LOC113014242	ENSACLP00000000479	ENSACLP00000022538	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.	Dystrobrevin binding protein 1b.	0.534
hps4	bloc1s3	ENSACLP00000000479	ENSACLP00000032692	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.	Biogenesis of lysosomal organelles complex-1, subunit 3.	0.536