48 items (Astatotilapia calliptera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSACLP00000037208	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (309 aa)
	ccs	Copper chaperone for superoxide dismutase. (305 aa)
	oser1	Oxidative stress responsive serine-rich 1. (357 aa)
	LOC113010656	Peroxiredoxin 1. (198 aa)
	ENSACLP00000018137	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (261 aa)
	ENSACLP00000016341	Pejvakin. (356 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (715 aa)
	ripk1	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (682 aa)
	prdx5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (190 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (594 aa)
	sod2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (225 aa)
	LOC113019113	Receptor-interacting serine-threonine kinase 3. (506 aa)
	tnfaip3	Tumor necrosis factor, alpha-induced protein 3. (818 aa)
	ENSACLP00000034814	Zinc finger protein 277. (440 aa)
	ENSACLP00000035402	C2H2-type domain-containing protein. (317 aa)
	ENSACLP00000035460	C2H2-type domain-containing protein. (405 aa)
	trpa1	Transient receptor potential cation channel, subfamily A, member 1b; Belongs to the transient receptor (TC 1.A.4) family. (1118 aa)
	impact	Impact RWD domain protein. (340 aa)
	LOC113026884	Uncharacterized protein. (477 aa)
	ncf1	Neutrophil cytosolic factor 1. (414 aa)
	LOC113030109	Lysine (K)-specific demethylase 6B, b. (1732 aa)
	romo1	Reactive oxygen species modulator 1. (79 aa)
	LOC113036079	Mitogen-activated protein kinase. (420 aa)
	LOC113021014	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
	aifm1	Apoptosis inducing factor mitochondrion associated 1. (650 aa)
	mapk7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1120 aa)
	LOC113026110	JunE proto-oncogene, AP-1 transcription factor subunit. (347 aa)
	edn1	Endothelin 1. (201 aa)
	smpd3	Sphingomyelin phosphodiesterase 3, neutral. (721 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	ENSACLP00000004294	Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (524 aa)
	sod1	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
	ect2	Epithelial cell transforming 2. (993 aa)
	LOC113027966	Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b. (407 aa)
	prdx3	Peroxiredoxin 3. (248 aa)
	ENSACLP00000028690	Lysine (K)-specific demethylase 6B, a. (2186 aa)
	sod3	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (215 aa)
	LOC113035495	Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (543 aa)
	LOC113032447	Peroxisome proliferator-activated receptor gamma, coactivator 1 beta. (912 aa)
	ENSACLP00000026032	Frataxin. (157 aa)
	LOC113011103	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (262 aa)
	LOC113011158	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (256 aa)
	LOC113011157	Aquaporin 1a (Colton blood group), tandem duplicate 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
	park7	Parkinson protein 7. (189 aa)
	nme9	NME/NM23 family member 8; Belongs to the NDK family. (635 aa)
	ENSACLP00000022536	Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (774 aa)
	ENSACLP00000022421	FA complementation group C. (497 aa)
	prdx2	Peroxiredoxin 2. (212 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000018137	ENSACLP00000028690	ENSACLP00000018137	ENSACLP00000028690	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Lysine (K)-specific demethylase 6B, a.	0.432
ENSACLP00000018137	LOC113021014	ENSACLP00000018137	ENSACLP00000011537	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.907
ENSACLP00000018137	LOC113030109	ENSACLP00000018137	ENSACLP00000012365	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Lysine (K)-specific demethylase 6B, b.	0.432
ENSACLP00000018137	LOC113036079	ENSACLP00000018137	ENSACLP00000011972	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.987
ENSACLP00000018137	mapk1	ENSACLP00000018137	ENSACLP00000005434	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.907
ENSACLP00000018137	mapk7	ENSACLP00000018137	ENSACLP00000010142	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.824
ENSACLP00000018137	nfe2l2	ENSACLP00000018137	ENSACLP00000012478	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Nuclear factor, erythroid 2-like 2a.	0.604
ENSACLP00000018137	sirt1	ENSACLP00000018137	ENSACLP00000030828	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Deacetylase sirtuin-type domain-containing protein.	0.737
ENSACLP00000026032	ENSACLP00000028690	ENSACLP00000026032	ENSACLP00000028690	Frataxin.	Lysine (K)-specific demethylase 6B, a.	0.412
ENSACLP00000026032	LOC113030109	ENSACLP00000026032	ENSACLP00000012365	Frataxin.	Lysine (K)-specific demethylase 6B, b.	0.412
ENSACLP00000026032	ccs	ENSACLP00000026032	ENSACLP00000021058	Frataxin.	Copper chaperone for superoxide dismutase.	0.463
ENSACLP00000026032	sod2	ENSACLP00000026032	ENSACLP00000030837	Frataxin.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.574
ENSACLP00000028690	ENSACLP00000018137	ENSACLP00000028690	ENSACLP00000018137	Lysine (K)-specific demethylase 6B, a.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.432
ENSACLP00000028690	ENSACLP00000026032	ENSACLP00000028690	ENSACLP00000026032	Lysine (K)-specific demethylase 6B, a.	Frataxin.	0.412
ENSACLP00000028690	LOC113026110	ENSACLP00000028690	ENSACLP00000007182	Lysine (K)-specific demethylase 6B, a.	JunE proto-oncogene, AP-1 transcription factor subunit.	0.432
ENSACLP00000028690	LOC113027966	ENSACLP00000028690	ENSACLP00000028953	Lysine (K)-specific demethylase 6B, a.	Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b.	0.837
ENSACLP00000028690	LOC113030109	ENSACLP00000028690	ENSACLP00000012365	Lysine (K)-specific demethylase 6B, a.	Lysine (K)-specific demethylase 6B, b.	0.802
ENSACLP00000028690	aifm1	ENSACLP00000028690	ENSACLP00000011216	Lysine (K)-specific demethylase 6B, a.	Apoptosis inducing factor mitochondrion associated 1.	0.422
ENSACLP00000028690	nme9	ENSACLP00000028690	ENSACLP00000023412	Lysine (K)-specific demethylase 6B, a.	NME/NM23 family member 8; Belongs to the NDK family.	0.762
ENSACLP00000028690	park7	ENSACLP00000028690	ENSACLP00000023901	Lysine (K)-specific demethylase 6B, a.	Parkinson protein 7.	0.452