STRINGSTRING
sirt6 sirt6 ENSACLP00000039327 ENSACLP00000039327 ENSACLP00000039284 ENSACLP00000039284 LOC113013393 LOC113013393 actr2 actr2 ENSACLP00000036088 ENSACLP00000036088 RNF8 RNF8 ENSACLP00000035605 ENSACLP00000035605 parp3 parp3 rad18 rad18 LOC113014662 LOC113014662 LOC113022928 LOC113022928 ENSACLP00000030469 ENSACLP00000030469 rad51 rad51 LOC113025855 LOC113025855 sirt7 sirt7 ufl1 ufl1 ARPC4 ARPC4 wrap53 wrap53 ENSACLP00000027693 ENSACLP00000027693 ENSACLP00000027601 ENSACLP00000027601 mre11 mre11 hus1 hus1 ENSACLP00000025627 ENSACLP00000025627 tonsl tonsl smarcad1 smarcad1 ENSACLP00000025050 ENSACLP00000025050 ENSACLP00000025034 ENSACLP00000025034 ENSACLP00000025028 ENSACLP00000025028 rpa3 rpa3 rec114 rec114 ENSACLP00000022919 ENSACLP00000022919 WDR70 WDR70 polh polh LOC113018933 LOC113018933 rbbp8 rbbp8 ddb1 ddb1 pnkp pnkp LOC113034961 LOC113034961 rad50 rad50 LOC113016588 LOC113016588 rnf169 rnf169 prpf19 prpf19 LOC113025194 LOC113025194 ENSACLP00000012686 ENSACLP00000012686 ENSACLP00000012654 ENSACLP00000012654 ENSACLP00000010589 ENSACLP00000010589 ENSACLP00000009352 ENSACLP00000009352 LOC113034173 LOC113034173 paxx paxx timeless timeless shld2 shld2 ENSACLP00000003992 ENSACLP00000003992 vcp vcp ENSACLP00000002055 ENSACLP00000002055 ENSACLP00000000349 ENSACLP00000000349 ENSACLP00000000266 ENSACLP00000000266 LOC113007917 LOC113007917 ENSACLP00000000176 ENSACLP00000000176 LOC113013852 LOC113013852
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sirt6Sirtuin 6. (351 aa)
ENSACLP00000039327HD domain-containing protein. (480 aa)
ENSACLP00000039284HD domain-containing protein. (540 aa)
LOC113013393SAM domain and HD domain 1. (622 aa)
actr2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (394 aa)
ENSACLP00000036088Actin related protein 2/3 complex, subunit 4. (260 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (464 aa)
ENSACLP00000035605Zgc:136908; Belongs to the AAA ATPase family. (721 aa)
parp3Poly [ADP-ribose] polymerase. (532 aa)
rad18RAD18 E3 ubiquitin protein ligase. (493 aa)
LOC113014662Mab-21 domain-containing protein. (512 aa)
LOC113022928SET domain and mariner transposase fusion gene. (316 aa)
ENSACLP00000030469Actin related protein 2/3 complex, subunit 3. (83 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (336 aa)
LOC113025855Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
sirt7Sirtuin 7. (405 aa)
ufl1UFM1-specific ligase 1. (801 aa)
ARPC4Actin related protein 2/3 complex subunit 4. (204 aa)
wrap53WD repeat containing, antisense to TP53. (545 aa)
ENSACLP00000027693Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (537 aa)
ENSACLP00000027601Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (537 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (707 aa)
hus1Checkpoint protein; Belongs to the HUS1 family. (285 aa)
ENSACLP00000025627Actin related protein 3B; Belongs to the actin family. (420 aa)
tonslTonsoku-like, DNA repair protein. (1445 aa)
smarcad1Uncharacterized protein. (1053 aa)
ENSACLP00000025050Uncharacterized protein. (255 aa)
ENSACLP00000025034Uncharacterized protein. (116 aa)
ENSACLP00000025028AAA_23 domain-containing protein. (53 aa)
rpa3Replication protein A3. (122 aa)
rec114REC114 meiotic recombination protein. (223 aa)
ENSACLP00000022919Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (999 aa)
WDR70WD repeat domain 70. (698 aa)
polhPolymerase (DNA directed), eta. (738 aa)
LOC113018933Zgc:101810; Belongs to the actin family. (394 aa)
rbbp8Uncharacterized protein. (670 aa)
ddb1Damage-specific DNA binding protein 1. (1140 aa)
pnkpPolynucleotide kinase 3'-phosphatase. (602 aa)
LOC113034961Uncharacterized protein. (1420 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
LOC113016588Uncharacterized protein; Belongs to the actin family. (427 aa)
rnf169Ring finger protein 169. (585 aa)
prpf19Pre-mRNA processing factor 19. (505 aa)
LOC113025194X-ray repair complementing defective repair in Chinese hamster cells 4. (334 aa)
ENSACLP00000012686Zinc-hook domain-containing protein. (1074 aa)
ENSACLP00000012654Ring finger protein 168. (411 aa)
ENSACLP00000010589Tumor protein p53 binding protein, 1. (1505 aa)
ENSACLP00000009352SMC5-SMC6 complex localization factor 1. (723 aa)
LOC113034173Uncharacterized protein. (237 aa)
paxxUncharacterized protein. (259 aa)
timelessTimeless circadian clock. (1249 aa)
shld2Si:ch211-134m17.9. (753 aa)
ENSACLP00000003992Uncharacterized protein. (32 aa)
vcpValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
ENSACLP00000002055Structural maintenance of chromosomes flexible hinge domain containing 1. (1782 aa)
ENSACLP00000000349HD domain-containing protein. (492 aa)
ENSACLP00000000266HD domain-containing protein. (627 aa)
LOC113007917Actin related protein 3; Belongs to the actin family. (453 aa)
ENSACLP00000000176HD domain-containing protein. (522 aa)
LOC113013852HD domain-containing protein. (746 aa)
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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