(44 nodes) Positive regulation of mitotic cell cycle network (Astatotilapia calliptera)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSACLP00000000444	Uncharacterized protein. (1863 aa)
	anapc7	Anaphase promoting complex subunit 7. (565 aa)
	cul4b	Cullin 4B; Belongs to the cullin family. (891 aa)
	lsm11	LSM11, U7 small nuclear RNA associated. (334 aa)
	AIF1	Allograft inflammatory factor 1. (146 aa)
	LSM10	LSM10, U7 small nuclear RNA associated. (123 aa)
	cdca5	Uncharacterized protein. (261 aa)
	ENSACLP00000009762	Chromatin licensing and DNA replication factor 1. (703 aa)
	LOC113036190	CULLIN_2 domain-containing protein; Belongs to the cullin family. (767 aa)
	LOC113034139	Homeobox domain-containing protein. (194 aa)
	cdc7	Cell division cycle 7 homolog (S. cerevisiae). (611 aa)
	rptor	Regulatory associated protein of MTOR, complex 1. (1350 aa)
	ENSACLP00000015199	APC11 anaphase promoting complex subunit 11 homolog (yeast). (94 aa)
	LOC113027151	Cyclin D2, a; Belongs to the cyclin family. (297 aa)
	stox1	Storkhead box 1. (1090 aa)
	rgcc	Regulator of cell cycle. (129 aa)
	rb1	Retinoblastoma 1. (912 aa)
	mblac1	Metallo-beta-lactamase domain containing 1. (220 aa)
	mtbp	MDM2 binding protein. (869 aa)
	cdc25b	Rhodanese domain-containing protein. (571 aa)
	LOC113013070	MBD domain-containing protein. (1059 aa)
	cdc27	Cell division cycle 27. (807 aa)
	LOC113013471	RAD51 paralog C. (359 aa)
	adam17	ADAM metallopeptidase domain 17b. (827 aa)
	ENSACLP00000021431	Cleavage and polyadenylation specific factor 3. (712 aa)
	ube2c	Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (174 aa)
	ppp1r10	Protein phosphatase 1, regulatory subunit 10. (807 aa)
	poldip2	Polymerase (DNA-directed), delta interacting protein 2. (377 aa)
	CCND1	Cyclin D1; Belongs to the cyclin family. (293 aa)
	anapc5	Anaphase promoting complex subunit 5. (771 aa)
	cdc23	CDC23 (cell division cycle 23, yeast, homolog). (595 aa)
	CPSF3	Cleavage and polyadenylation specific factor 3. (637 aa)
	ttl	Tubulin tyrosine ligase. (410 aa)
	nsmce2	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (230 aa)
	ENSACLP00000029365	Lysine (K)-specific methyltransferase 2E. (1232 aa)
	LOC113009062	Cyclin D2, b; Belongs to the cyclin family. (294 aa)
	sass6	SAS-6 centriolar assembly protein. (588 aa)
	stil	STIL centriolar assembly protein. (1075 aa)
	ENSACLP00000035328	Cullin 4A; Belongs to the cullin family. (760 aa)
	mad2l1bp	MAD2L1 binding protein. (385 aa)
	cdc16	Cell division cycle 16 homolog (S. cerevisiae). (619 aa)
	CUL3	Cullin 3; Belongs to the cullin family. (766 aa)
	lgmn	Legumain. (434 aa)
	plrg1	Pleiotropic regulator 1. (513 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIF1	anapc5	ENSACLP00000002443	ENSACLP00000025381	Allograft inflammatory factor 1.	Anaphase promoting complex subunit 5.	0.492
AIF1	cdc16	ENSACLP00000002443	ENSACLP00000039031	Allograft inflammatory factor 1.	Cell division cycle 16 homolog (S. cerevisiae).	0.474
CCND1	CUL3	ENSACLP00000024023	ENSACLP00000040546	Cyclin D1; Belongs to the cyclin family.	Cullin 3; Belongs to the cullin family.	0.722
CCND1	ENSACLP00000000444	ENSACLP00000024023	ENSACLP00000000444	Cyclin D1; Belongs to the cyclin family.	Uncharacterized protein.	0.416
CCND1	LOC113009062	ENSACLP00000024023	ENSACLP00000029886	Cyclin D1; Belongs to the cyclin family.	Cyclin D2, b; Belongs to the cyclin family.	0.849
CCND1	LOC113027151	ENSACLP00000024023	ENSACLP00000016060	Cyclin D1; Belongs to the cyclin family.	Cyclin D2, a; Belongs to the cyclin family.	0.849
CCND1	LOC113036190	ENSACLP00000024023	ENSACLP00000010678	Cyclin D1; Belongs to the cyclin family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.722
CCND1	cdc25b	ENSACLP00000024023	ENSACLP00000019949	Cyclin D1; Belongs to the cyclin family.	Rhodanese domain-containing protein.	0.875
CCND1	rb1	ENSACLP00000024023	ENSACLP00000019169	Cyclin D1; Belongs to the cyclin family.	Retinoblastoma 1.	0.964
CPSF3	ENSACLP00000021431	ENSACLP00000027766	ENSACLP00000021431	Cleavage and polyadenylation specific factor 3.	Cleavage and polyadenylation specific factor 3.	0.829
CPSF3	LSM10	ENSACLP00000027766	ENSACLP00000007007	Cleavage and polyadenylation specific factor 3.	LSM10, U7 small nuclear RNA associated.	0.893
CPSF3	cdc23	ENSACLP00000027766	ENSACLP00000026463	Cleavage and polyadenylation specific factor 3.	CDC23 (cell division cycle 23, yeast, homolog).	0.461
CPSF3	lsm11	ENSACLP00000027766	ENSACLP00000002137	Cleavage and polyadenylation specific factor 3.	LSM11, U7 small nuclear RNA associated.	0.560
CUL3	CCND1	ENSACLP00000040546	ENSACLP00000024023	Cullin 3; Belongs to the cullin family.	Cyclin D1; Belongs to the cyclin family.	0.722
CUL3	ENSACLP00000009762	ENSACLP00000040546	ENSACLP00000009762	Cullin 3; Belongs to the cullin family.	Chromatin licensing and DNA replication factor 1.	0.529
CUL3	ENSACLP00000035328	ENSACLP00000040546	ENSACLP00000035328	Cullin 3; Belongs to the cullin family.	Cullin 4A; Belongs to the cullin family.	0.707
CUL3	LOC113009062	ENSACLP00000040546	ENSACLP00000029886	Cullin 3; Belongs to the cullin family.	Cyclin D2, b; Belongs to the cyclin family.	0.722
CUL3	LOC113013471	ENSACLP00000040546	ENSACLP00000021115	Cullin 3; Belongs to the cullin family.	RAD51 paralog C.	0.460
CUL3	LOC113027151	ENSACLP00000040546	ENSACLP00000016060	Cullin 3; Belongs to the cullin family.	Cyclin D2, a; Belongs to the cyclin family.	0.722
CUL3	LOC113036190	ENSACLP00000040546	ENSACLP00000010678	Cullin 3; Belongs to the cullin family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.829