STRINGSTRING
fgf19 fgf19 LOC113030381 LOC113030381 dkk3 dkk3 ppargc1a ppargc1a PPTC7 PPTC7 dusp12 dusp12 prmt3 prmt3 ENSACLP00000002706 ENSACLP00000002706 ak4 ak4 lepr lepr ENSACLP00000003077 ENSACLP00000003077 LOC113021753 LOC113021753 LOC113021648 LOC113021648 foxk1 foxk1 ppard ppard igf2 igf2 LOC113022594 LOC113022594 sirt6 sirt6 LOC113014966 LOC113014966 LOC113022113 LOC113022113 ppara ppara midn midn etfbkmt etfbkmt ENSACLP00000006511 ENSACLP00000006511 ENSACLP00000006648 ENSACLP00000006648 ogt ogt ENSACLP00000007302 ENSACLP00000007302 LOC113008593 LOC113008593 ENSACLP00000009186 ENSACLP00000009186 acadm acadm pid1 pid1 ENSACLP00000009796 ENSACLP00000009796 DKK3 DKK3 LOC113035561 LOC113035561 ENSACLP00000010348 ENSACLP00000010348 acmsd acmsd prkn prkn c1qtnf6 c1qtnf6 cda cda slc7a11 slc7a11 LOC113021435 LOC113021435 ephx2 ephx2 IGFBP4 IGFBP4 ENSACLP00000013582 ENSACLP00000013582 ENSACLP00000014165 ENSACLP00000014165 pdk1 pdk1 ENSACLP00000014347 ENSACLP00000014347 ptgs2 ptgs2 mlycd mlycd abcg1 abcg1 usp7 usp7 LOC113031642 LOC113031642 LOC113027155 LOC113027155 LOC113010029 LOC113010029 fgf1 fgf1 ENSACLP00000017703 ENSACLP00000017703 nr1h3 nr1h3 LOC113016364 LOC113016364 LOC113016489 LOC113016489 LOC113016660 LOC113016660 ddb1 ddb1 ENSACLP00000018362 ENSACLP00000018362 ENSACLP00000018580 ENSACLP00000018580 LOC113016615 LOC113016615 ENSACLP00000018932 ENSACLP00000018932 wdtc1 wdtc1 ENSACLP00000019192 ENSACLP00000019192 prkaa2 prkaa2 h6pd h6pd ENSACLP00000020455 ENSACLP00000020455 ncs1 ncs1 ENSACLP00000020957 ENSACLP00000020957 LOC113021131 LOC113021131 htr2a htr2a plek plek abcg4 abcg4 LOC113013152 LOC113013152 lacc1 lacc1 nr1d1 nr1d1 ENSACLP00000022919 ENSACLP00000022919 ENSACLP00000023046 ENSACLP00000023046 ncor2 ncor2 LOC113033598 LOC113033598 DGKQ DGKQ srebf2 srebf2 PPARG PPARG zmpste24 zmpste24 lcmt1 lcmt1 ENSACLP00000024954 ENSACLP00000024954 LOC113011617 LOC113011617 JMJD8 JMJD8 LOC113028096 LOC113028096 LOC113025795 LOC113025795 pibf1 pibf1 zbtb20 zbtb20 sirt4 sirt4 SOGA1 SOGA1 tspo tspo snai2 snai2 ttc39b ttc39b LOC113008612 LOC113008612 ENSACLP00000027782 ENSACLP00000027782 LOC113027597 LOC113027597 rusc1 rusc1 LOC113036871 LOC113036871 sirt7 sirt7 guca1a guca1a LOC113020236 LOC113020236 LOC113009616 LOC113009616 LOC113007418 LOC113007418 gnmt gnmt sirt1 sirt1 LOC113010708 LOC113010708 arl2 arl2 bad bad flcn flcn bckdk bckdk LOC113016680 LOC113016680 slc27a4 slc27a4 LOC113009976 LOC113009976 LOC113037288 LOC113037288 TTC39B TTC39B ENSACLP00000033115 ENSACLP00000033115 ENSACLP00000033130 ENSACLP00000033130 fam3c fam3c P2RY6 P2RY6 ENSACLP00000033805 ENSACLP00000033805 pdk3 pdk3 rd3 rd3 lpgat1 lpgat1 ENSACLP00000034747 ENSACLP00000034747 LOC113021701 LOC113021701 sirt5 sirt5 ENSACLP00000035117 ENSACLP00000035117 ENSACLP00000035615 ENSACLP00000035615 ENSACLP00000035628 ENSACLP00000035628 pdk4 pdk4 LOC113028088 LOC113028088 ENSACLP00000036121 ENSACLP00000036121 FOXK2 FOXK2 lpcat3 lpcat3 LOC113027476 LOC113027476 bend3 bend3 p2rx7 p2rx7 LOC113030849 LOC113030849 PPARA PPARA clybl clybl dab2 dab2 LOC113030867 LOC113030867 LOC113030640 LOC113030640 ENSACLP00000040080 ENSACLP00000040080 ENSACLP00000040408 ENSACLP00000040408 gckr gckr nr1h4 nr1h4 arv1 arv1 ENSACLP00000041064 ENSACLP00000041064 prkaa1 prkaa1 srebf1 srebf1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC113030381Guanylate cyclase activator 1d. (188 aa)
dkk3Dickkopf WNT signaling pathway inhibitor 3a. (270 aa)
ppargc1aPeroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (1275 aa)
PPTC7Protein phosphatase; Belongs to the PP2C family. (297 aa)
dusp12Dual specificity phosphatase 12. (299 aa)
prmt3Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (525 aa)
ENSACLP00000002706Fumarate hydratase. (508 aa)
ak4GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (226 aa)
leprLeptin receptor. (1181 aa)
ENSACLP00000003077Ubiquitin-like domain-containing protein. (363 aa)
LOC113021753Uncharacterized protein. (106 aa)
LOC113021648Uncharacterized protein. (108 aa)
foxk1Forkhead box K1. (671 aa)
ppardPeroxisome proliferator-activated receptor delta b. (509 aa)
igf2Insulin-like growth factor 2b. (215 aa)
LOC113022594Nuclear receptor subfamily 1, group D, member 4b. (587 aa)
sirt6Sirtuin 6. (351 aa)
LOC113014966Apolipoprotein Ea. (262 aa)
LOC113022113Tribbles pseudokinase 3. (353 aa)
pparaPeroxisome proliferator-activated receptor alpha a. (476 aa)
midnMidnolin. (566 aa)
etfbkmtElectron transfer flavoprotein subunit beta lysine methyltransferase. (258 aa)
ENSACLP00000006511Battenin. (378 aa)
ENSACLP00000006648Battenin. (415 aa)
ogtO-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1. (1038 aa)
ENSACLP00000007302SREBF chaperone. (1271 aa)
LOC113008593ATP-binding cassette, sub-family D (ALD), member 2. (737 aa)
ENSACLP00000009186Nuclear protein 1a. (73 aa)
acadmAcyl-CoA dehydrogenase medium chain. (424 aa)
pid1Phosphotyrosine interaction domain containing 1. (225 aa)
ENSACLP00000009796Uncharacterized protein. (112 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (270 aa)
LOC113035561Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
ENSACLP00000010348Nuclear receptor corepressor 1. (2152 aa)
acmsd2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa)
prknE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (456 aa)
c1qtnf6C1q and TNF related 6b. (242 aa)
cdaCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (165 aa)
slc7a11Solute carrier family 7 member 11. (494 aa)
LOC113021435Zgc:158403. (565 aa)
ephx2Epoxide hydrolase 2, cytoplasmic. (561 aa)
IGFBP4Insulin like growth factor binding protein 4. (260 aa)
ENSACLP00000013582Uncharacterized protein. (1377 aa)
ENSACLP00000014165Zgc:103586. (134 aa)
pdk1Protein-serine/threonine kinase. (429 aa)
ENSACLP00000014347Uncharacterized protein. (114 aa)
ptgs2Prostaglandin-endoperoxide synthase 2b. (620 aa)
mlycdMalonyl-CoA decarboxylase. (504 aa)
abcg1ATP-binding cassette, sub-family G (WHITE), member 1. (723 aa)
usp7Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1112 aa)
LOC113031642Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
LOC113027155TP53 induced glycolysis regulatory phosphatase a. (271 aa)
LOC113010029ATCAY kinesin light chain interacting caytaxin b. (352 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (182 aa)
ENSACLP00000017703G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (386 aa)
nr1h3Nuclear receptor subfamily 1, group H, member 3. (464 aa)
LOC113016364Dimethylaniline monooxygenase [N-oxide-forming]. (553 aa)
LOC113016489Dimethylaniline monooxygenase [N-oxide-forming]. (551 aa)
LOC113016660Dimethylaniline monooxygenase [N-oxide-forming]. (568 aa)
ddb1Damage-specific DNA binding protein 1. (1140 aa)
ENSACLP00000018362Serine/threonine-protein kinase TOR. (2384 aa)
ENSACLP00000018580Dimethylaniline monooxygenase [N-oxide-forming]. (530 aa)
LOC113016615Dimethylaniline monooxygenase [N-oxide-forming]. (561 aa)
ENSACLP00000018932Flavin-containing monooxygenase. (204 aa)
wdtc1WD and tetratricopeptide repeats 1. (675 aa)
ENSACLP00000019192Trypsin domain containing 1. (556 aa)
prkaa2Non-specific serine/threonine protein kinase. (557 aa)
h6pdHexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase). (791 aa)
ENSACLP00000020455Uncharacterized protein. (490 aa)
ncs1Uncharacterized protein. (222 aa)
ENSACLP00000020957Peroxiredoxin like 2C. (209 aa)
LOC113021131E1A binding protein p300 b. (2771 aa)
htr2a5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a. (501 aa)
plekPleckstrin. (351 aa)
abcg4ATP-binding cassette, sub-family G (WHITE), member 4a. (642 aa)
LOC113013152Nuclear receptor subfamily 1, group H, member 5. (515 aa)
lacc1Laccase (multicopper oxidoreductase) domain containing 1. (414 aa)
nr1d1Nuclear receptor subfamily 1, group d, member 1. (598 aa)
ENSACLP00000022919Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (999 aa)
ENSACLP00000023046Si:dkey-6n21.13; Belongs to the G-protein coupled receptor 1 family. (374 aa)
ncor2Nuclear receptor corepressor 2. (2362 aa)
LOC113033598Si:dkey-190g11.3. (220 aa)
DGKQDiacylglycerol kinase. (919 aa)
srebf2Sterol regulatory element binding transcription factor 2. (1178 aa)
PPARGPeroxisome proliferator activated receptor gamma. (536 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
lcmt1Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (339 aa)
ENSACLP00000024954DnaJ (Hsp40) homolog, subfamily C, member 30b. (190 aa)
LOC113011617Apolipoprotein Ba. (4368 aa)
JMJD8Jumonji domain containing 8. (309 aa)
LOC113028096Cytochrome c oxidase assembly homolog 11 (yeast). (257 aa)
LOC113025795Protein phosphatase; Belongs to the PP2C family. (297 aa)
pibf1Progesterone immunomodulatory binding factor 1. (766 aa)
zbtb20Zinc finger and BTB domain containing 20. (700 aa)
sirt4NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (311 aa)
SOGA1Suppressor of glucose, autophagy associated 1. (1918 aa)
tspoTranslocator protein. (161 aa)
snai2Snail family zinc finger 2. (260 aa)
ttc39bTetratricopeptide repeat domain 39B. (580 aa)
LOC113008612Si:ch73-352p4.8. (525 aa)
ENSACLP00000027782J domain-containing protein. (202 aa)
LOC113027597E1A binding protein p300 a. (2787 aa)
rusc1Uncharacterized protein. (1901 aa)
LOC113036871ATP-binding cassette, sub-family G (WHITE), member 4b. (645 aa)
sirt7Sirtuin 7. (405 aa)
guca1aGuanylate cyclase activator 1A. (202 aa)
LOC113020236Forkhead box K2. (607 aa)
LOC113009616TP53 induced glycolysis regulatory phosphatase b. (312 aa)
LOC113007418RAN binding protein 2. (3055 aa)
gnmtGlycine N-methyltransferase. (295 aa)
sirt1Deacetylase sirtuin-type domain-containing protein. (715 aa)
LOC113010708NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (306 aa)
arl2ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
badBCL2 associated agonist of cell death b. (158 aa)
flcnFolliculin. (556 aa)
bckdkProtein-serine/threonine kinase. (445 aa)
LOC113016680ATCAY kinesin light chain interacting caytaxin a. (374 aa)
slc27a4Solute carrier family 27 member 4. (655 aa)
LOC113009976FATP synthase c subunit lysine N-methyltransferase. (208 aa)
LOC113037288Apolipoprotein Bb, tandem duplicate 2. (3682 aa)
TTC39BTetratricopeptide repeat domain 39B. (587 aa)
ENSACLP00000033115Vitellogenin domain-containing protein. (752 aa)
ENSACLP00000033130Uncharacterized protein. (420 aa)
fam3cFamily with sequence similarity 3 member C. (227 aa)
P2RY6Pyrimidinergic receptor P2Y6. (329 aa)
ENSACLP00000033805Uncharacterized protein. (480 aa)
pdk3Protein-serine/threonine kinase. (425 aa)
rd3Retinal degeneration 3, GUCY2D regulator. (220 aa)
lpgat1Lysophosphatidylglycerol acyltransferase 1. (372 aa)
ENSACLP00000034747Tetratricopeptide repeat domain 39A. (566 aa)
LOC113021701Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (165 aa)
sirt5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (372 aa)
ENSACLP00000035117Uncharacterized protein. (139 aa)
ENSACLP00000035615Uncharacterized protein. (196 aa)
ENSACLP00000035628Interleukin-1. (114 aa)
pdk4Protein-serine/threonine kinase. (475 aa)
LOC113028088Protein-serine/threonine kinase. (409 aa)
ENSACLP00000036121Uncharacterized protein. (134 aa)
FOXK2Forkhead box K2. (615 aa)
lpcat3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (464 aa)
LOC113027476Uncharacterized protein. (161 aa)
bend3BEN domain containing 3. (818 aa)
p2rx7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (580 aa)
LOC113030849PDZ domain containing 3b. (545 aa)
PPARAPeroxisome proliferator-activated receptor alpha b. (501 aa)
clyblCitrate lyase beta like. (343 aa)
dab2DAB adaptor protein 2. (778 aa)
LOC113030867Flavin-containing monooxygenase. (431 aa)
LOC113030640G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)
ENSACLP00000040080Podocan. (586 aa)
ENSACLP00000040408Uncharacterized protein. (665 aa)
gckrUncharacterized protein. (602 aa)
nr1h4Nuclear receptor subfamily 1, group H, member 4. (485 aa)
arv1ARV1 homolog, fatty acid homeostasis modulator. (239 aa)
ENSACLP00000041064Apolipoprotein Eb. (288 aa)
prkaa1Non-specific serine/threonine protein kinase. (571 aa)
srebf1Sterol regulatory element binding transcription factor 1. (1176 aa)
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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