(49 nodes) Response to interleukin-1 network (Astatotilapia calliptera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSACLP00000027284	Uncharacterized protein. (545 aa)
	LOC113007562	Zmp:0000000936. (639 aa)
	ENSACLP00000028014	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (153 aa)
	YTHDC2	YTH domain containing 2. (1364 aa)
	ENSACLP00000028276	A kinase (PRKA) anchor protein 12b. (1482 aa)
	LOC113012803	Hyaluronidase. (441 aa)
	tnfrsf11a	Tumor necrosis factor receptor superfamily, member 11a, NFKB activator. (649 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (602 aa)
	rbmx	RNA binding motif protein X-linked. (391 aa)
	usp10	Ubiquitin carboxyl-terminal hydrolase. (879 aa)
	ENSACLP00000003323	SCY domain-containing protein. (119 aa)
	ENSACLP00000003656	Chemokine (C-C motif) ligand 25b. (119 aa)
	LOC113027223	SCY domain-containing protein. (99 aa)
	LOC113027224	SCY domain-containing protein. (99 aa)
	ENSACLP00000005703	SCY domain-containing protein. (96 aa)
	LOC113027227	SCY domain-containing protein. (99 aa)
	LOC113027227-2	Monocyte chemotactic protein 1B-like. (99 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (630 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (439 aa)
	LOC113014938	Si:dkey-206d17.12. (644 aa)
	ENSACLP00000008684	Immunoresponsive gene 1, like. (475 aa)
	LOC113034139	Homeobox domain-containing protein. (194 aa)
	ENSACLP00000012123	Ribosomal protein S6 kinase. (785 aa)
	ENSACLP00000013396	SCY domain-containing protein. (102 aa)
	LOC113030441	Ribosomal protein S6 kinase. (784 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (576 aa)
	ENSACLP00000016489	CARD domain-containing protein. (93 aa)
	ENSACLP00000016500	CARD domain-containing protein. (101 aa)
	ENSACLP00000016507	CARD domain-containing protein. (95 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (571 aa)
	LOC113032849	CARD domain-containing protein. (174 aa)
	ENSACLP00000016947	CARD domain-containing protein. (95 aa)
	ENSACLP00000017063	Uncharacterized protein. (198 aa)
	LOC113017367	C-C motif chemokine. (91 aa)
	LOC113017357	C-C motif chemokine. (91 aa)
	pcsk1	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (769 aa)
	tank	TRAF family member-associated NFKB activator. (335 aa)
	irak1	Interleukin-1 receptor-associated kinase 1. (745 aa)
	nr1d1	Nuclear receptor subfamily 1, group d, member 1. (598 aa)
	ST18	ST18 C2H2C-type zinc finger transcription factor. (1130 aa)
	ENSACLP00000035615	Uncharacterized protein. (196 aa)
	ENSACLP00000035628	Interleukin-1. (114 aa)
	LOC113031917	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (754 aa)
	ENSACLP00000039844	Aconitate decarboxylase 1. (475 aa)
	ENSACLP00000040066	Uncharacterized protein. (472 aa)
	rc3h1	Ring finger and CCCH-type domains 1b. (1125 aa)
	LOC113030608	CARD domain-containing protein. (199 aa)
	ENSACLP00000040197	CARD domain-containing protein. (91 aa)
	LOC113032406	Zinc finger CCCH-type containing 12A. (632 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000003323	ENSACLP00000005703	ENSACLP00000003323	ENSACLP00000005703	SCY domain-containing protein.	SCY domain-containing protein.	0.503
ENSACLP00000003323	LOC113017357	ENSACLP00000003323	ENSACLP00000018254	SCY domain-containing protein.	C-C motif chemokine.	0.540
ENSACLP00000003323	LOC113017367	ENSACLP00000003323	ENSACLP00000018210	SCY domain-containing protein.	C-C motif chemokine.	0.540
ENSACLP00000003323	LOC113027223	ENSACLP00000003323	ENSACLP00000005673	SCY domain-containing protein.	SCY domain-containing protein.	0.503
ENSACLP00000003323	LOC113027224	ENSACLP00000003323	ENSACLP00000005688	SCY domain-containing protein.	SCY domain-containing protein.	0.503
ENSACLP00000003323	LOC113027227	ENSACLP00000003323	ENSACLP00000005748	SCY domain-containing protein.	SCY domain-containing protein.	0.503
ENSACLP00000003323	LOC113027227-2	ENSACLP00000003323	ENSACLP00000005794	SCY domain-containing protein.	Monocyte chemotactic protein 1B-like.	0.503
ENSACLP00000003656	ENSACLP00000005703	ENSACLP00000003656	ENSACLP00000005703	Chemokine (C-C motif) ligand 25b.	SCY domain-containing protein.	0.503
ENSACLP00000003656	LOC113017357	ENSACLP00000003656	ENSACLP00000018254	Chemokine (C-C motif) ligand 25b.	C-C motif chemokine.	0.540
ENSACLP00000003656	LOC113017367	ENSACLP00000003656	ENSACLP00000018210	Chemokine (C-C motif) ligand 25b.	C-C motif chemokine.	0.540
ENSACLP00000003656	LOC113027223	ENSACLP00000003656	ENSACLP00000005673	Chemokine (C-C motif) ligand 25b.	SCY domain-containing protein.	0.503
ENSACLP00000003656	LOC113027224	ENSACLP00000003656	ENSACLP00000005688	Chemokine (C-C motif) ligand 25b.	SCY domain-containing protein.	0.503
ENSACLP00000003656	LOC113027227	ENSACLP00000003656	ENSACLP00000005748	Chemokine (C-C motif) ligand 25b.	SCY domain-containing protein.	0.503
ENSACLP00000003656	LOC113027227-2	ENSACLP00000003656	ENSACLP00000005794	Chemokine (C-C motif) ligand 25b.	Monocyte chemotactic protein 1B-like.	0.503
ENSACLP00000005703	ENSACLP00000003323	ENSACLP00000005703	ENSACLP00000003323	SCY domain-containing protein.	SCY domain-containing protein.	0.503
ENSACLP00000005703	ENSACLP00000003656	ENSACLP00000005703	ENSACLP00000003656	SCY domain-containing protein.	Chemokine (C-C motif) ligand 25b.	0.503
ENSACLP00000005703	ENSACLP00000013396	ENSACLP00000005703	ENSACLP00000013396	SCY domain-containing protein.	SCY domain-containing protein.	0.503
ENSACLP00000008684	ENSACLP00000039844	ENSACLP00000008684	ENSACLP00000039844	Immunoresponsive gene 1, like.	Aconitate decarboxylase 1.	0.851
ENSACLP00000012123	LOC113030441	ENSACLP00000012123	ENSACLP00000014332	Ribosomal protein S6 kinase.	Ribosomal protein S6 kinase.	0.849
ENSACLP00000013396	ENSACLP00000005703	ENSACLP00000013396	ENSACLP00000005703	SCY domain-containing protein.	SCY domain-containing protein.	0.503