(39 nodes) Positive regulation of DNA biosynthetic process network (Astatotilapia calliptera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cct5	Chaperonin containing TCP1, subunit 5 (epsilon). (541 aa)
	grem1	Gremlin 1a, DAN family BMP antagonist. (179 aa)
	nox4	FAD-binding FR-type domain-containing protein. (559 aa)
	NEK2	NIMA-related kinase 2. (425 aa)
	nek2	NIMA-related kinase 2. (446 aa)
	rfc5	Replication factor C (activator 1) 5. (335 aa)
	LOC113035495	Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (543 aa)
	LOC113026054	Uncharacterized protein. (296 aa)
	chtf18	AAA domain-containing protein. (922 aa)
	ENSACLP00000001223	Uncharacterized protein. (496 aa)
	rfc4	Replication factor C (activator 1) 4. (357 aa)
	map3k4	Mitogen-activated protein kinase kinase kinase 4. (1581 aa)
	ENSACLP00000004087	Uncharacterized protein. (139 aa)
	gins3	GINS complex subunit 3. (211 aa)
	ENSACLP00000004131	TAN domain-containing protein. (177 aa)
	ENSACLP00000004294	Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (524 aa)
	polg2	Polymerase (DNA directed), gamma 2, accessory subunit. (455 aa)
	rfc3	Replication factor C (activator 1) 3. (356 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (439 aa)
	ENSACLP00000008384	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2524 aa)
	cct3	T-complex protein 1 subunit gamma. (541 aa)
	nvl	Nuclear VCP like. (864 aa)
	gins2	DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (180 aa)
	pdgfb	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (554 aa)
	gins4	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (224 aa)
	rfc2	Replication factor C (activator 1) 2. (356 aa)
	cct2	Chaperonin containing TCP1, subunit 2 (beta). (551 aa)
	pnkp	Polynucleotide kinase 3'-phosphatase. (602 aa)
	rgcc	Regulator of cell cycle. (129 aa)
	LOC113021108	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (515 aa)
	gfer	Sulfhydryl oxidase. (197 aa)
	mapkapk5	MAPK activated protein kinase 5. (471 aa)
	ENSACLP00000021335	Protection of telomeres 1 homolog. (696 aa)
	fbxo4	F-box protein 4. (396 aa)
	ENSACLP00000023026	Dyskeratosis congenita 1, dyskerin. (491 aa)
	xrcc5	X-ray repair complementing defective repair in Chinese hamster cells 5. (739 aa)
	ENSACLP00000025109	Uncharacterized protein. (413 aa)
	chtf8	CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (136 aa)
	wrap53	WD repeat containing, antisense to TP53. (545 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000001223	ENSACLP00000021335	ENSACLP00000001223	ENSACLP00000021335	Uncharacterized protein.	Protection of telomeres 1 homolog.	0.991
ENSACLP00000001223	ENSACLP00000023026	ENSACLP00000001223	ENSACLP00000023026	Uncharacterized protein.	Dyskeratosis congenita 1, dyskerin.	0.692
ENSACLP00000001223	wrap53	ENSACLP00000001223	ENSACLP00000027950	Uncharacterized protein.	WD repeat containing, antisense to TP53.	0.664
ENSACLP00000004087	ENSACLP00000004131	ENSACLP00000004087	ENSACLP00000004131	Uncharacterized protein.	TAN domain-containing protein.	0.690
ENSACLP00000004087	ENSACLP00000004294	ENSACLP00000004087	ENSACLP00000004294	Uncharacterized protein.	Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.	0.407
ENSACLP00000004087	ENSACLP00000008384	ENSACLP00000004087	ENSACLP00000008384	Uncharacterized protein.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.993
ENSACLP00000004087	LOC113035495	ENSACLP00000004087	ENSACLP00000028068	Uncharacterized protein.	Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.	0.407
ENSACLP00000004087	rfc2	ENSACLP00000004087	ENSACLP00000015610	Uncharacterized protein.	Replication factor C (activator 1) 2.	0.845
ENSACLP00000004087	rfc3	ENSACLP00000004087	ENSACLP00000005448	Uncharacterized protein.	Replication factor C (activator 1) 3.	0.835
ENSACLP00000004087	rfc4	ENSACLP00000004087	ENSACLP00000001974	Uncharacterized protein.	Replication factor C (activator 1) 4.	0.845
ENSACLP00000004087	rfc5	ENSACLP00000004087	ENSACLP00000034324	Uncharacterized protein.	Replication factor C (activator 1) 5.	0.834
ENSACLP00000004087	xrcc5	ENSACLP00000004087	ENSACLP00000024019	Uncharacterized protein.	X-ray repair complementing defective repair in Chinese hamster cells 5.	0.930
ENSACLP00000004131	ENSACLP00000004087	ENSACLP00000004131	ENSACLP00000004087	TAN domain-containing protein.	Uncharacterized protein.	0.690
ENSACLP00000004131	ENSACLP00000004294	ENSACLP00000004131	ENSACLP00000004294	TAN domain-containing protein.	Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.	0.407
ENSACLP00000004131	ENSACLP00000008384	ENSACLP00000004131	ENSACLP00000008384	TAN domain-containing protein.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.994
ENSACLP00000004131	LOC113035495	ENSACLP00000004131	ENSACLP00000028068	TAN domain-containing protein.	Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.	0.407
ENSACLP00000004131	rfc2	ENSACLP00000004131	ENSACLP00000015610	TAN domain-containing protein.	Replication factor C (activator 1) 2.	0.845
ENSACLP00000004131	rfc3	ENSACLP00000004131	ENSACLP00000005448	TAN domain-containing protein.	Replication factor C (activator 1) 3.	0.835
ENSACLP00000004131	rfc4	ENSACLP00000004131	ENSACLP00000001974	TAN domain-containing protein.	Replication factor C (activator 1) 4.	0.845
ENSACLP00000004131	rfc5	ENSACLP00000004131	ENSACLP00000034324	TAN domain-containing protein.	Replication factor C (activator 1) 5.	0.834