(49 nodes) Negative regulation of response to DNA damage stimulus network (Astatotilapia calliptera)

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSACLP00000008753	Uncharacterized protein. (436 aa)
	LOC113034173	Uncharacterized protein. (237 aa)
	trip12	Thyroid hormone receptor interactor 12. (2056 aa)
	ercc6	Excision repair cross-complementation group 6. (1439 aa)
	ENSACLP00000009814	AAA domain-containing protein. (866 aa)
	ENSACLP00000010589	Tumor protein p53 binding protein, 1. (1505 aa)
	cdkn2d	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
	recql5	RecQ helicase-like 5. (1018 aa)
	chek2	Checkpoint kinase 2. (523 aa)
	yju2	YJU2 splicing factor homolog. (340 aa)
	ENSACLP00000014741	Tripartite motif containing 32. (671 aa)
	rnf169	Ring finger protein 169. (585 aa)
	radx	RPA1 related single stranded DNA binding protein. (843 aa)
	otub1	Ubiquitin thioesterase. (279 aa)
	ubr5	Ubiquitin protein ligase E3 component n-recognin 5. (2855 aa)
	triap1	TP53 regulated inhibitor of apoptosis 1. (74 aa)
	LOC113024490	Uncharacterized protein. (1009 aa)
	ddias	Rep_fac-A_C domain-containing protein. (789 aa)
	ENSACLP00000019507	Clusterin; Belongs to the clusterin family. (440 aa)
	ENSACLP00000020797	Uncharacterized protein. (83 aa)
	LOC113007511	Uncharacterized protein. (179 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (852 aa)
	ppp1r10	Protein phosphatase 1, regulatory subunit 10. (807 aa)
	parpbp	PARP1 binding protein. (587 aa)
	thoc1	THO complex 1. (654 aa)
	ENSACLP00000024782	Uncharacterized protein. (211 aa)
	ercc4	Excision repair cross-complementation group 4. (899 aa)
	ercc1	Excision repair cross-complementation group 1. (352 aa)
	snai2	Snail family zinc finger 2. (260 aa)
	tpt1	Tumor protein, translationally-controlled 1; Belongs to the TCTP family. (170 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (715 aa)
	marchf7	Membrane-associated ring finger (C3HC4) 7. (783 aa)
	OTUB2	OTU deubiquitinase, ubiquitin aldehyde binding 2. (227 aa)
	LOC113014662	Mab-21 domain-containing protein. (512 aa)
	psmd10	Proteasome 26S subunit, non-ATPase 10. (226 aa)
	clu	Clusterin; Belongs to the clusterin family. (462 aa)
	rmi2	RecQ mediated genome instability 2. (146 aa)
	LOC113008278	Atypical chemokine receptor 3a; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	tmem161a	Transmembrane protein 161A. (496 aa)
	fbh1	F-box DNA helicase 1. (1077 aa)
	LOC113032033	Uncharacterized protein. (182 aa)
	LOC113007064	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (463 aa)
	shld2	Si:ch211-134m17.9. (753 aa)
	bcl2l12	Si:ch73-248e21.1. (356 aa)
	xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1. (627 aa)
	ENSACLP00000002055	Structural maintenance of chromosomes flexible hinge domain containing 1. (1782 aa)
	ENSACLP00000001994	ATPase family AAA domain containing 5a. (1510 aa)
	usp47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1383 aa)
	CLUL1	Clusterin; Belongs to the clusterin family. (465 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000001994	ENSACLP00000010589	ENSACLP00000001994	ENSACLP00000010589	ATPase family AAA domain containing 5a.	Tumor protein p53 binding protein, 1.	0.404
ENSACLP00000001994	chek2	ENSACLP00000001994	ENSACLP00000013461	ATPase family AAA domain containing 5a.	Checkpoint kinase 2.	0.605
ENSACLP00000001994	ercc4	ENSACLP00000001994	ENSACLP00000025304	ATPase family AAA domain containing 5a.	Excision repair cross-complementation group 4.	0.753
ENSACLP00000001994	fbh1	ENSACLP00000001994	ENSACLP00000006307	ATPase family AAA domain containing 5a.	F-box DNA helicase 1.	0.747
ENSACLP00000001994	recql5	ENSACLP00000001994	ENSACLP00000012242	ATPase family AAA domain containing 5a.	RecQ helicase-like 5.	0.704
ENSACLP00000001994	rmi2	ENSACLP00000001994	ENSACLP00000008132	ATPase family AAA domain containing 5a.	RecQ mediated genome instability 2.	0.602
ENSACLP00000001994	xrcc1	ENSACLP00000001994	ENSACLP00000002286	ATPase family AAA domain containing 5a.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.625
ENSACLP00000008753	ercc1	ENSACLP00000008753	ENSACLP00000025684	Uncharacterized protein.	Excision repair cross-complementation group 1.	0.984
ENSACLP00000008753	ercc4	ENSACLP00000008753	ENSACLP00000025304	Uncharacterized protein.	Excision repair cross-complementation group 4.	0.985
ENSACLP00000009814	ENSACLP00000010589	ENSACLP00000009814	ENSACLP00000010589	AAA domain-containing protein.	Tumor protein p53 binding protein, 1.	0.404
ENSACLP00000009814	chek2	ENSACLP00000009814	ENSACLP00000013461	AAA domain-containing protein.	Checkpoint kinase 2.	0.605
ENSACLP00000009814	ercc4	ENSACLP00000009814	ENSACLP00000025304	AAA domain-containing protein.	Excision repair cross-complementation group 4.	0.753
ENSACLP00000009814	fbh1	ENSACLP00000009814	ENSACLP00000006307	AAA domain-containing protein.	F-box DNA helicase 1.	0.747
ENSACLP00000009814	recql5	ENSACLP00000009814	ENSACLP00000012242	AAA domain-containing protein.	RecQ helicase-like 5.	0.704
ENSACLP00000009814	rmi2	ENSACLP00000009814	ENSACLP00000008132	AAA domain-containing protein.	RecQ mediated genome instability 2.	0.602
ENSACLP00000009814	xrcc1	ENSACLP00000009814	ENSACLP00000002286	AAA domain-containing protein.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.625
ENSACLP00000010589	ENSACLP00000001994	ENSACLP00000010589	ENSACLP00000001994	Tumor protein p53 binding protein, 1.	ATPase family AAA domain containing 5a.	0.404
ENSACLP00000010589	ENSACLP00000009814	ENSACLP00000010589	ENSACLP00000009814	Tumor protein p53 binding protein, 1.	AAA domain-containing protein.	0.404
ENSACLP00000010589	LOC113034173	ENSACLP00000010589	ENSACLP00000009124	Tumor protein p53 binding protein, 1.	Uncharacterized protein.	0.475
ENSACLP00000010589	chek2	ENSACLP00000010589	ENSACLP00000013461	Tumor protein p53 binding protein, 1.	Checkpoint kinase 2.	0.994