(78 nodes) Perinuclear region of cytoplasm network (Astatotilapia calliptera)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sirt2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (382 aa)
	ENSACLP00000012316	Oxysterol-binding protein; Belongs to the OSBP family. (911 aa)
	LOC113029294	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (182 aa)
	LOC113029295	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (186 aa)
	LOC113029296	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (186 aa)
	LOC113029297	Apolipoprotein Db; Belongs to the calycin superfamily. Lipocalin family. (182 aa)
	LOC113029262	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (190 aa)
	mtdh	Uncharacterized protein. (533 aa)
	LOC113024330	Protein kinase domain-containing protein. (550 aa)
	ENSACLP00000026516	Oxysterol-binding protein; Belongs to the OSBP family. (670 aa)
	ENSACLP00000026637	N-acetyltransferase domain-containing protein. (214 aa)
	LOC113024895	Cryptochrome circadian regulator 5. (533 aa)
	ENSACLP00000019853	Nanos homolog 1; Belongs to the nanos family. (185 aa)
	epo	Erythropoietin; Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Belongs to the EPO/TPO family. (185 aa)
	ENSACLP00000028094	Ran GTPase activating protein 1b. (564 aa)
	LOC113019702	Monoacylglycerol O-acyltransferase 3a. (335 aa)
	ENSACLP00000020452	Uncharacterized protein. (319 aa)
	rangap1	RAN GTPase activating protein 1a. (578 aa)
	ENSACLP00000020820	Nanos-type domain-containing protein; Belongs to the nanos family. (236 aa)
	LOC113015766	Oxysterol-binding protein; Belongs to the OSBP family. (975 aa)
	ENSACLP00000021743	Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A. (258 aa)
	ENSACLP00000022097	Metadherin a. (401 aa)
	gak	Cyclin G associated kinase. (1317 aa)
	ENSACLP00000028276	A kinase (PRKA) anchor protein 12b. (1482 aa)
	magi2	Membrane associated guanylate kinase, WW and PDZ domain containing 2a. (1536 aa)
	LOC113011333	Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
	ENSACLP00000029694	Uncharacterized protein. (1089 aa)
	SRC	Tyrosine-protein kinase. (550 aa)
	wbp2	WW domain binding protein 2. (263 aa)
	OSBPL1A	Oxysterol-binding protein; Belongs to the OSBP family. (889 aa)
	LOC113013605	Uncharacterized protein. (224 aa)
	ENSACLP00000033415	PCNA clamp associated factor. (94 aa)
	LOC113020616	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (377 aa)
	rundc1	RUN domain containing 1. (569 aa)
	LOC113006549	Nuclear receptor binding protein 1. (534 aa)
	ENSACLP00000034439	Phosphoinositide kinase, FYVE finger containing. (2087 aa)
	ENSACLP00000035547	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b. (233 aa)
	ENSACLP00000035617	Oxysterol-binding protein; Belongs to the OSBP family. (565 aa)
	ENSACLP00000036317	annotation not available (319 aa)
	nrde2	NRDE-2, necessary for RNA interference, domain containing. (1186 aa)
	ENSACLP00000037293	Oxysterol-binding protein; Belongs to the OSBP family. (759 aa)
	ENSACLP00000038215	Lymphocyte antigen 6 family member pge. (100 aa)
	mogat2	Monoacylglycerol O-acyltransferase 2. (335 aa)
	OSBP	Oxysterol-binding protein; Belongs to the OSBP family. (778 aa)
	LOC113026941	Membrane associated guanylate kinase, WW and PDZ domain containing 2b. (1575 aa)
	myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (288 aa)
	ENSACLP00000006155	Forkhead box P3b. (390 aa)
	osbpl3	Oxysterol-binding protein; Belongs to the OSBP family. (850 aa)
	hmgcll1	3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1. (341 aa)
	AANAT	Arylalkylamine N-acetyltransferase 1. (202 aa)
	ENSACLP00000005103	Oxysterol-binding protein; Belongs to the OSBP family. (755 aa)
	ENSACLP00000004744	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (414 aa)
	LOC113021312	Oxysterol-binding protein; Belongs to the OSBP family. (922 aa)
	ENSACLP00000003839	DEXH (Asp-Glu-X-His) box polypeptide 58. (679 aa)
	ENSACLP00000003814	DEXH (Asp-Glu-X-His) box polypeptide 58. (677 aa)
	ENSACLP00000002940	DnaJ (Hsp40) homolog, subfamily C, member 6. (923 aa)
	LOC113014677	Oxysterol-binding protein; Belongs to the OSBP family. (818 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (381 aa)
	cd34	Si:ch211-286o17.1. (341 aa)
	ENSACLP00000001722	Uncharacterized protein. (330 aa)
	ENSACLP00000010422	Arylalkylamine N-acetyltransferase 2. (233 aa)
	ENSACLP00000010416	Uncharacterized protein. (324 aa)
	LOC113030532	Monoacylglycerol O-acyltransferase 3b. (326 aa)
	dcun1d3	DCN1-like protein. (326 aa)
	hif1an	Hypoxia inducible factor 1 subunit alpha inhibitor. (354 aa)
	bspry	Uncharacterized protein. (467 aa)
	atraid	All-trans retinoic acid-induced differentiation factor. (231 aa)
	LOC113011397	Apolipoprotein Da, duplicate 1; Belongs to the calycin superfamily. Lipocalin family. (186 aa)
	creb3l2	cAMP responsive element binding protein 3-like 2. (548 aa)
	ENSACLP00000023214	Uncharacterized protein. (337 aa)
	ENSACLP00000024080	Epithelial cell adhesion molecule. (298 aa)
	ENSACLP00000024108	Si:dkey-43k4.5; Belongs to the potassium channel family. (506 aa)
	LOC113035381	Epithelial cell adhesion molecule. (306 aa)
	wdr44	WD repeat domain 44. (906 aa)
	wbp2nl	WBP2 N-terminal like. (283 aa)
	tmem134	Transmembrane protein 134. (203 aa)
	LOC113013184	Tyrosine-protein kinase. (552 aa)
	fbxl5	F-box and leucine-rich repeat protein 5. (697 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AANAT	ENSACLP00000010422	ENSACLP00000005145	ENSACLP00000010422	Arylalkylamine N-acetyltransferase 1.	Arylalkylamine N-acetyltransferase 2.	0.849
AANAT	ENSACLP00000026637	ENSACLP00000005145	ENSACLP00000026637	Arylalkylamine N-acetyltransferase 1.	N-acetyltransferase domain-containing protein.	0.848
AANAT	hmgcll1	ENSACLP00000005145	ENSACLP00000005334	Arylalkylamine N-acetyltransferase 1.	3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1.	0.459
ENSACLP00000002940	ENSACLP00000034439	ENSACLP00000002940	ENSACLP00000034439	DnaJ (Hsp40) homolog, subfamily C, member 6.	Phosphoinositide kinase, FYVE finger containing.	0.562
ENSACLP00000002940	LOC113013184	ENSACLP00000002940	ENSACLP00000025858	DnaJ (Hsp40) homolog, subfamily C, member 6.	Tyrosine-protein kinase.	0.458
ENSACLP00000002940	LOC113026941	ENSACLP00000002940	ENSACLP00000039989	DnaJ (Hsp40) homolog, subfamily C, member 6.	Membrane associated guanylate kinase, WW and PDZ domain containing 2b.	0.619
ENSACLP00000002940	SRC	ENSACLP00000002940	ENSACLP00000031792	DnaJ (Hsp40) homolog, subfamily C, member 6.	Tyrosine-protein kinase.	0.458
ENSACLP00000002940	epo	ENSACLP00000002940	ENSACLP00000027784	DnaJ (Hsp40) homolog, subfamily C, member 6.	Erythropoietin; Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Belongs to the EPO/TPO family.	0.567
ENSACLP00000002940	gak	ENSACLP00000002940	ENSACLP00000028221	DnaJ (Hsp40) homolog, subfamily C, member 6.	Cyclin G associated kinase.	0.993
ENSACLP00000002940	magi2	ENSACLP00000002940	ENSACLP00000028677	DnaJ (Hsp40) homolog, subfamily C, member 6.	Membrane associated guanylate kinase, WW and PDZ domain containing 2a.	0.619
ENSACLP00000003814	ENSACLP00000033415	ENSACLP00000003814	ENSACLP00000033415	DEXH (Asp-Glu-X-His) box polypeptide 58.	PCNA clamp associated factor.	0.439
ENSACLP00000003839	ENSACLP00000033415	ENSACLP00000003839	ENSACLP00000033415	DEXH (Asp-Glu-X-His) box polypeptide 58.	PCNA clamp associated factor.	0.439
ENSACLP00000004744	sirt2	ENSACLP00000004744	ENSACLP00000017528	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.558
ENSACLP00000005103	gak	ENSACLP00000005103	ENSACLP00000028221	Oxysterol-binding protein; Belongs to the OSBP family.	Cyclin G associated kinase.	0.532
ENSACLP00000010422	AANAT	ENSACLP00000010422	ENSACLP00000005145	Arylalkylamine N-acetyltransferase 2.	Arylalkylamine N-acetyltransferase 1.	0.849
ENSACLP00000010422	ENSACLP00000026637	ENSACLP00000010422	ENSACLP00000026637	Arylalkylamine N-acetyltransferase 2.	N-acetyltransferase domain-containing protein.	0.850
ENSACLP00000010422	hmgcll1	ENSACLP00000010422	ENSACLP00000005334	Arylalkylamine N-acetyltransferase 2.	3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1.	0.459
ENSACLP00000012316	gak	ENSACLP00000012316	ENSACLP00000028221	Oxysterol-binding protein; Belongs to the OSBP family.	Cyclin G associated kinase.	0.532
ENSACLP00000026516	gak	ENSACLP00000026516	ENSACLP00000028221	Oxysterol-binding protein; Belongs to the OSBP family.	Cyclin G associated kinase.	0.532
ENSACLP00000026637	AANAT	ENSACLP00000026637	ENSACLP00000005145	N-acetyltransferase domain-containing protein.	Arylalkylamine N-acetyltransferase 1.	0.848