23 items (Astatotilapia calliptera) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

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gene fusions

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co-expression

protein homology

Your Input:
	LOC113036949	Glucuronokinase with putative uridyl pyrophosphorylase. (622 aa)
	eftud2	Elongation factor Tu GTP binding domain containing 2. (971 aa)
	galk1	Galactokinase 1. (393 aa)
	gfm2	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (769 aa)
	mvk	Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
	EFL1	Elongation factor like GTPase 1. (1110 aa)
	ENSACLP00000038160	Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family. (356 aa)
	ENSACLP00000036091	MutL homolog 3 (E. coli). (1171 aa)
	LOC113016085	Tr-type G domain-containing protein. (858 aa)
	lonp2	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (842 aa)
	rps2	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (279 aa)
	ENSACLP00000031218	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (735 aa)
	lonp1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1002 aa)
	rps16	Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (146 aa)
	top2b	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1602 aa)
	gfm1	Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...] (748 aa)
	pms2	PMS1 homolog 2, mismatch repair system component. (861 aa)
	ENSACLP00000019245	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1503 aa)
	mrps9	Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (400 aa)
	galk2	Galactokinase 2. (458 aa)
	mvd	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (402 aa)
	eef2	Eukaryotic translation elongation factor 2b. (859 aa)
	pms1	PMS1 homolog 1, mismatch repair system component. (897 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFL1	ENSACLP00000019245	ENSACLP00000038190	ENSACLP00000019245	Elongation factor like GTPase 1.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.561
EFL1	ENSACLP00000038160	ENSACLP00000038190	ENSACLP00000038160	Elongation factor like GTPase 1.	Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	0.966
EFL1	mrps9	ENSACLP00000038190	ENSACLP00000015879	Elongation factor like GTPase 1.	Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.983
EFL1	rps16	ENSACLP00000038190	ENSACLP00000026419	Elongation factor like GTPase 1.	Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family.	0.905
EFL1	rps2	ENSACLP00000038190	ENSACLP00000041528	Elongation factor like GTPase 1.	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.	0.966
EFL1	top2b	ENSACLP00000038190	ENSACLP00000025733	Elongation factor like GTPase 1.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.561
ENSACLP00000019245	EFL1	ENSACLP00000019245	ENSACLP00000038190	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Elongation factor like GTPase 1.	0.561
ENSACLP00000019245	ENSACLP00000031218	ENSACLP00000019245	ENSACLP00000031218	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.438
ENSACLP00000019245	ENSACLP00000038160	ENSACLP00000019245	ENSACLP00000038160	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	0.435
ENSACLP00000019245	LOC113016085	ENSACLP00000019245	ENSACLP00000034886	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Tr-type G domain-containing protein.	0.491
ENSACLP00000019245	eef2	ENSACLP00000019245	ENSACLP00000004582	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Eukaryotic translation elongation factor 2b.	0.491
ENSACLP00000019245	eftud2	ENSACLP00000019245	ENSACLP00000001977	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Elongation factor Tu GTP binding domain containing 2.	0.443
ENSACLP00000019245	gfm2	ENSACLP00000019245	ENSACLP00000040752	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.599
ENSACLP00000019245	mrps9	ENSACLP00000019245	ENSACLP00000015879	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.509
ENSACLP00000019245	rps2	ENSACLP00000019245	ENSACLP00000041528	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.	0.442
ENSACLP00000031218	ENSACLP00000019245	ENSACLP00000031218	ENSACLP00000019245	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.438
ENSACLP00000031218	ENSACLP00000036091	ENSACLP00000031218	ENSACLP00000036091	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	MutL homolog 3 (E. coli).	0.995
ENSACLP00000031218	mrps9	ENSACLP00000031218	ENSACLP00000015879	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.434
ENSACLP00000031218	pms1	ENSACLP00000031218	ENSACLP00000004103	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	PMS1 homolog 1, mismatch repair system component.	0.996
ENSACLP00000031218	pms2	ENSACLP00000031218	ENSACLP00000022142	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	PMS1 homolog 2, mismatch repair system component.	0.999