(5 nodes) 5-3 exonuclease, C-terminal domain superfamily network (Astatotilapia calliptera)

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Your Input:
	ercc5	Excision repair cross-complementation group 5. (1115 aa)
	ENSACLP00000007406	Exonuclease 1. (775 aa)
	ENSACLP00000013892	Zgc:110269. (354 aa)
	fen1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (381 aa)
	gen1	Uncharacterized protein. (893 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000007406	ENSACLP00000013892	ENSACLP00000007406	ENSACLP00000013892	Exonuclease 1.	Zgc:110269.	0.903
ENSACLP00000007406	ercc5	ENSACLP00000007406	ENSACLP00000035831	Exonuclease 1.	Excision repair cross-complementation group 5.	0.446
ENSACLP00000007406	fen1	ENSACLP00000007406	ENSACLP00000028668	Exonuclease 1.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.903
ENSACLP00000007406	gen1	ENSACLP00000007406	ENSACLP00000029931	Exonuclease 1.	Uncharacterized protein.	0.765
ENSACLP00000013892	ENSACLP00000007406	ENSACLP00000013892	ENSACLP00000007406	Zgc:110269.	Exonuclease 1.	0.903
ENSACLP00000013892	ercc5	ENSACLP00000013892	ENSACLP00000035831	Zgc:110269.	Excision repair cross-complementation group 5.	0.493
ENSACLP00000013892	fen1	ENSACLP00000013892	ENSACLP00000028668	Zgc:110269.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.856
ENSACLP00000013892	gen1	ENSACLP00000013892	ENSACLP00000029931	Zgc:110269.	Uncharacterized protein.	0.830
ercc5	ENSACLP00000007406	ENSACLP00000035831	ENSACLP00000007406	Excision repair cross-complementation group 5.	Exonuclease 1.	0.446
ercc5	ENSACLP00000013892	ENSACLP00000035831	ENSACLP00000013892	Excision repair cross-complementation group 5.	Zgc:110269.	0.493
ercc5	fen1	ENSACLP00000035831	ENSACLP00000028668	Excision repair cross-complementation group 5.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.493
ercc5	gen1	ENSACLP00000035831	ENSACLP00000029931	Excision repair cross-complementation group 5.	Uncharacterized protein.	0.683
fen1	ENSACLP00000007406	ENSACLP00000028668	ENSACLP00000007406	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Exonuclease 1.	0.903
fen1	ENSACLP00000013892	ENSACLP00000028668	ENSACLP00000013892	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Zgc:110269.	0.856
fen1	ercc5	ENSACLP00000028668	ENSACLP00000035831	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Excision repair cross-complementation group 5.	0.493
fen1	gen1	ENSACLP00000028668	ENSACLP00000029931	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.830
gen1	ENSACLP00000007406	ENSACLP00000029931	ENSACLP00000007406	Uncharacterized protein.	Exonuclease 1.	0.765
gen1	ENSACLP00000013892	ENSACLP00000029931	ENSACLP00000013892	Uncharacterized protein.	Zgc:110269.	0.830
gen1	ercc5	ENSACLP00000029931	ENSACLP00000035831	Uncharacterized protein.	Excision repair cross-complementation group 5.	0.683
gen1	fen1	ENSACLP00000029931	ENSACLP00000028668	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.830