11 items (Astatotilapia calliptera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113033859	Uncharacterized protein. (927 aa)
	ENSACLP00000022835	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (352 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (305 aa)
	LOC113011047	Mitogen-activated protein kinase kinase 2b. (395 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	LOC113021014	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
	LOC113012951	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (296 aa)
	LOC113024985	Fibroblast growth factor receptor substrate 2b. (525 aa)
	LOC113022018	Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (202 aa)
	LOC113016221	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (421 aa)
	ENSACLP00000041401	Rap guanine nucleotide exchange factor (GEF) 1b. (1042 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACLP00000022835	LOC113011047	ENSACLP00000022835	ENSACLP00000003805	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 2b.	0.829
ENSACLP00000022835	LOC113016221	ENSACLP00000022835	ENSACLP00000034218	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.	0.833
ENSACLP00000022835	LOC113021014	ENSACLP00000022835	ENSACLP00000011537	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.949
ENSACLP00000022835	mapk1	ENSACLP00000022835	ENSACLP00000005434	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.949
ENSACLP00000041401	LOC113012951	ENSACLP00000041401	ENSACLP00000012544	Rap guanine nucleotide exchange factor (GEF) 1b.	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	0.584
ENSACLP00000041401	LOC113024985	ENSACLP00000041401	ENSACLP00000031175	Rap guanine nucleotide exchange factor (GEF) 1b.	Fibroblast growth factor receptor substrate 2b.	0.741
ENSACLP00000041401	LOC113033859	ENSACLP00000041401	ENSACLP00000013518	Rap guanine nucleotide exchange factor (GEF) 1b.	Uncharacterized protein.	0.821
ENSACLP00000041401	crkl	ENSACLP00000041401	ENSACLP00000029556	Rap guanine nucleotide exchange factor (GEF) 1b.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.966
LOC113011047	ENSACLP00000022835	ENSACLP00000003805	ENSACLP00000022835	Mitogen-activated protein kinase kinase 2b.	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	0.829
LOC113011047	LOC113016221	ENSACLP00000003805	ENSACLP00000034218	Mitogen-activated protein kinase kinase 2b.	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.	0.832
LOC113011047	LOC113021014	ENSACLP00000003805	ENSACLP00000011537	Mitogen-activated protein kinase kinase 2b.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.949
LOC113011047	mapk1	ENSACLP00000003805	ENSACLP00000005434	Mitogen-activated protein kinase kinase 2b.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.949
LOC113012951	ENSACLP00000041401	ENSACLP00000012544	ENSACLP00000041401	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	Rap guanine nucleotide exchange factor (GEF) 1b.	0.584
LOC113012951	LOC113022018	ENSACLP00000012544	ENSACLP00000033270	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family.	0.849
LOC113012951	LOC113024985	ENSACLP00000012544	ENSACLP00000031175	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	Fibroblast growth factor receptor substrate 2b.	0.564
LOC113012951	LOC113033859	ENSACLP00000012544	ENSACLP00000013518	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	Uncharacterized protein.	0.584
LOC113012951	crkl	ENSACLP00000012544	ENSACLP00000029556	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.493
LOC113016221	ENSACLP00000022835	ENSACLP00000034218	ENSACLP00000022835	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	0.833
LOC113016221	LOC113011047	ENSACLP00000034218	ENSACLP00000003805	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase 2b.	0.832
LOC113016221	LOC113021014	ENSACLP00000034218	ENSACLP00000011537	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.949