STRINGSTRING
cbx6 cbx6 LOC113031861 LOC113031861 LOC113027513 LOC113027513 LOC113012864 LOC113012864 RPS27A RPS27A ENSACLP00000004152 ENSACLP00000004152 LOC113027683 LOC113027683 LOC113027683-2 LOC113027683-2 cdk4 cdk4 EZH1 EZH1 mapk1 mapk1 ENSACLP00000006047 ENSACLP00000006047 LOC113011815 LOC113011815 ENSACLP00000006388 ENSACLP00000006388 map2k7 map2k7 LOC113014472 LOC113014472 ENSACLP00000006657 ENSACLP00000006657 ENSACLP00000006670 ENSACLP00000006670 ENSACLP00000006681 ENSACLP00000006681 ENSACLP00000006709 ENSACLP00000006709 LOC113018712 LOC113018712 LOC113026110 LOC113026110 mapkapk2 mapkapk2 mdm4 mdm4 ENSACLP00000009605 ENSACLP00000009605 suz12 suz12 tnik tnik LOC113034495 LOC113034495 LOC113008649 LOC113008649 ENSACLP00000011125 ENSACLP00000011125 LOC113024610 LOC113024610 LOC113022696 LOC113022696 cdkn2d cdkn2d LOC113021014 LOC113021014 LOC113036079 LOC113036079 LOC113009105 LOC113009105 LOC113030109 LOC113030109 ENSACLP00000012684 ENSACLP00000012684 ENSACLP00000012764 ENSACLP00000012764 ENSACLP00000012767 ENSACLP00000012767 LOC113030103 LOC113030103 NPTX1 NPTX1 cbx8 cbx8 LOC113023624 LOC113023624 RING1 RING1 eed eed LOC113013098 LOC113013098 LOC113021112 LOC113021112 LOC113027683-3 LOC113027683-3 LOC113027683-4 LOC113027683-4 ENSACLP00000017804 ENSACLP00000017804 ENSACLP00000017828 ENSACLP00000017828 ENSACLP00000017878 ENSACLP00000017878 ENSACLP00000017898 ENSACLP00000017898 ENSACLP00000018041 ENSACLP00000018041 ENSACLP00000018114 ENSACLP00000018114 ENSACLP00000018137 ENSACLP00000018137 ENSACLP00000018190 ENSACLP00000018190 ENSACLP00000018263 ENSACLP00000018263 ENSACLP00000018275 ENSACLP00000018275 LOC113018910 LOC113018910 ENSACLP00000018306 ENSACLP00000018306 ENSACLP00000018350 ENSACLP00000018350 LOC113018911 LOC113018911 ENSACLP00000018440 ENSACLP00000018440 ENSACLP00000018553 ENSACLP00000018553 ENSACLP00000018590 ENSACLP00000018590 ENSACLP00000018737 ENSACLP00000018737 ENSACLP00000018876 ENSACLP00000018876 ENSACLP00000018916 ENSACLP00000018916 ENSACLP00000019020 ENSACLP00000019020 LOC113008654 LOC113008654 ENSACLP00000019026 ENSACLP00000019026 ENSACLP00000019052 ENSACLP00000019052 H2AZ1 H2AZ1 ENSACLP00000019116 ENSACLP00000019116 LOC113008654-2 LOC113008654-2 LOC113006738 LOC113006738 mapkapk5 mapkapk5 ENSACLP00000020044 ENSACLP00000020044 ENSACLP00000020155 ENSACLP00000020155 ENSACLP00000020378 ENSACLP00000020378 LOC113021152 LOC113021152 ENSACLP00000021612 ENSACLP00000021612 ENSACLP00000021626 ENSACLP00000021626 ENSACLP00000021637 ENSACLP00000021637 ENSACLP00000021747 ENSACLP00000021747 ENSACLP00000021798 ENSACLP00000021798 ENSACLP00000021837 ENSACLP00000021837 ENSACLP00000021919 ENSACLP00000021919 ENSACLP00000021962 ENSACLP00000021962 ENSACLP00000022030 ENSACLP00000022030 H4-16 H4-16 ENSACLP00000022379 ENSACLP00000022379 LOC113008652 LOC113008652 ENSACLP00000022682 ENSACLP00000022682 LOC113028594 LOC113028594 ENSACLP00000023020 ENSACLP00000023020 ENSACLP00000023387 ENSACLP00000023387 nme9 nme9 ENSACLP00000023454 ENSACLP00000023454 ENSACLP00000023615 ENSACLP00000023615 ENSACLP00000023776 ENSACLP00000023776 ENSACLP00000023814 ENSACLP00000023814 ENSACLP00000023827 ENSACLP00000023827 ENSACLP00000023958 ENSACLP00000023958 ENSACLP00000023998 ENSACLP00000023998 ENSACLP00000024183 ENSACLP00000024183 LOC113035672 LOC113035672 CBX2 CBX2 ENSACLP00000026173 ENSACLP00000026173 LOC113010915 LOC113010915 SCML2 SCML2 LOC113027596 LOC113027596 LOC113008059 LOC113008059 LOC113022853 LOC113022853 ENSACLP00000028690 ENSACLP00000028690 LOC113020216 LOC113020216 cbx2 cbx2 map2k4 map2k4 LOC113020374 LOC113020374 LOC113032720 LOC113032720 LOC113028005 LOC113028005 LOC113033077 LOC113033077 CDKN2A CDKN2A bmi1 bmi1 ENSACLP00000033001 ENSACLP00000033001 H3-3B H3-3B ENSACLP00000033341 ENSACLP00000033341 ENSACLP00000033485 ENSACLP00000033485 cdk6 cdk6 ezh2 ezh2 ENSACLP00000034906 ENSACLP00000034906 ENSACLP00000034976 ENSACLP00000034976 LOC113033615 LOC113033615 ENSACLP00000035755 ENSACLP00000035755 MAPKAPK3 MAPKAPK3 LOC113011809 LOC113011809 MAP2K6 MAP2K6 fosl2 fosl2 ENSACLP00000038872 ENSACLP00000038872 ENSACLP00000039028 ENSACLP00000039028 ENSACLP00000039140 ENSACLP00000039140 ENSACLP00000039196 ENSACLP00000039196 map3k5 map3k5 scmh1 scmh1 LOC113015812 LOC113015812 LOC113020834 LOC113020834 LOC113020844 LOC113020844 LOC113020841 LOC113020841
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cbx6Chromo domain-containing protein. (509 aa)
LOC113031861Si:ch211-1i11.3. (1326 aa)
LOC113027513Retinoblastoma binding protein 4, like. (427 aa)
LOC113012864Mitogen-activated protein kinase. (361 aa)
RPS27ARibosomal protein S27a. (212 aa)
ENSACLP00000004152Histone H3; Belongs to the histone H3 family. (94 aa)
LOC113027683Histone H3; Belongs to the histone H3 family. (136 aa)
LOC113027683-2Histone H3.3. (136 aa)
cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (306 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (766 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
ENSACLP00000006047Mitogen-activated protein kinase. (402 aa)
LOC113011815Retinoblastoma binding protein 4. (424 aa)
ENSACLP00000006388Histone H2A; Belongs to the histone H2A family. (140 aa)
map2k7Mitogen-activated protein kinase kinase 7. (439 aa)
LOC113014472WD_REPEATS_REGION domain-containing protein. (426 aa)
ENSACLP00000006657Histone H3; Belongs to the histone H3 family. (140 aa)
ENSACLP00000006670Histone H2A; Belongs to the histone H2A family. (131 aa)
ENSACLP00000006681Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (145 aa)
ENSACLP00000006709Histone H2B; Belongs to the histone H2B family. (134 aa)
LOC113018712Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (384 aa)
LOC113026110JunE proto-oncogene, AP-1 transcription factor subunit. (347 aa)
mapkapk2MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (389 aa)
mdm4MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (495 aa)
ENSACLP00000009605Ubiquitin B. (723 aa)
suz12SUZ12 polycomb repressive complex 2 subunit b. (691 aa)
tnikTRAF2 and NCK interacting kinase a. (1511 aa)
LOC113034495Mitogen-activated protein kinase. (456 aa)
LOC113008649Histone H3. (136 aa)
ENSACLP00000011125Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (95 aa)
LOC113024610Neuronal pentraxin receptor b. (597 aa)
LOC113022696Mitogen-activated protein kinase. (361 aa)
cdkn2dCyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
LOC113021014Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
LOC113036079Mitogen-activated protein kinase. (420 aa)
LOC113009105Mitogen-activated protein kinase. (361 aa)
LOC113030109Lysine (K)-specific demethylase 6B, b. (1732 aa)
ENSACLP00000012684Histone H2A; Belongs to the histone H2A family. (127 aa)
ENSACLP00000012764Histone H3; Belongs to the histone H3 family. (90 aa)
ENSACLP00000012767Histone H2A; Belongs to the histone H2A family. (114 aa)
LOC113030103Uncharacterized protein. (3518 aa)
NPTX1Uncharacterized protein. (427 aa)
cbx8Chromobox homolog 8b. (361 aa)
LOC113023624Chromobox 4. (647 aa)
RING1Ring finger protein 1. (395 aa)
eedEmbryonic ectoderm development. (443 aa)
LOC113013098Mitogen-activated protein kinase. (364 aa)
LOC113021112Neuronal pentraxin receptor a. (555 aa)
LOC113027683-3Histone H3.3. (136 aa)
LOC113027683-4Histone H3.3. (136 aa)
ENSACLP00000017804Uncharacterized protein; Belongs to the histone H2A family. (242 aa)
ENSACLP00000017828Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa)
ENSACLP00000017878Uncharacterized protein. (137 aa)
ENSACLP00000017898Histone H2A; Belongs to the histone H2A family. (131 aa)
ENSACLP00000018041Histone H3; Belongs to the histone H3 family. (91 aa)
ENSACLP00000018114Thioredoxin; Belongs to the thioredoxin family. (110 aa)
ENSACLP00000018137Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (261 aa)
ENSACLP00000018190Histone H2A; Belongs to the histone H2A family. (134 aa)
ENSACLP00000018263annotation not available (91 aa)
ENSACLP00000018275Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (144 aa)
LOC113018910Thioredoxin; Belongs to the thioredoxin family. (130 aa)
ENSACLP00000018306Uncharacterized protein. (125 aa)
ENSACLP00000018350Histone H2B; Belongs to the histone H2B family. (159 aa)
LOC113018911Thioredoxin; Belongs to the thioredoxin family. (107 aa)
ENSACLP00000018440Histone H3; Belongs to the histone H3 family. (95 aa)
ENSACLP00000018553Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ENSACLP00000018590Histone H3; Belongs to the histone H3 family. (136 aa)
ENSACLP00000018737Histone domain-containing protein. (178 aa)
ENSACLP00000018876Histone H3; Belongs to the histone H3 family. (97 aa)
ENSACLP00000018916Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa)
ENSACLP00000019020Histone H2B; Belongs to the histone H2B family. (112 aa)
LOC113008654Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ENSACLP00000019026Histone H2A; Belongs to the histone H2A family. (134 aa)
ENSACLP00000019052Histone H2A; Belongs to the histone H2A family. (133 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (128 aa)
ENSACLP00000019116Histone H3; Belongs to the histone H3 family. (138 aa)
LOC113008654-2Histone H4. (103 aa)
LOC113006738V-fos FBJ murine osteosarcoma viral oncogene homolog Ab. (376 aa)
mapkapk5MAPK activated protein kinase 5. (471 aa)
ENSACLP00000020044Uncharacterized protein. (548 aa)
ENSACLP00000020155Misshapen-like kinase 1. (517 aa)
ENSACLP00000020378CNH domain-containing protein. (283 aa)
LOC113021152Chromobox homolog 7a. (357 aa)
ENSACLP00000021612Histone H2B; Belongs to the histone H2B family. (153 aa)
ENSACLP00000021626Histone H2A; Belongs to the histone H2A family. (129 aa)
ENSACLP00000021637Histone H3; Belongs to the histone H3 family. (93 aa)
ENSACLP00000021747Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (146 aa)
ENSACLP00000021798Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (104 aa)
ENSACLP00000021837Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (83 aa)
ENSACLP00000021919Histone H2A; Belongs to the histone H2A family. (140 aa)
ENSACLP00000021962Histone H3; Belongs to the histone H3 family. (139 aa)
ENSACLP00000022030Histone H2B; Belongs to the histone H2B family. (63 aa)
H4-16Histone H4. (103 aa)
ENSACLP00000022379Histone H2A; Belongs to the histone H2A family. (154 aa)
LOC113008652Histone H2B 1/2. (124 aa)
ENSACLP00000022682Histone domain-containing protein. (143 aa)
LOC113028594Neuronal pentraxin IIb. (438 aa)
ENSACLP00000023020Histone H3; Belongs to the histone H3 family. (91 aa)
ENSACLP00000023387Uncharacterized protein; Belongs to the histone H2A family. (232 aa)
nme9NME/NM23 family member 8; Belongs to the NDK family. (635 aa)
ENSACLP00000023454Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
ENSACLP00000023615Histone H3; Belongs to the histone H3 family. (108 aa)
ENSACLP00000023776Histone H2B; Belongs to the histone H2B family. (111 aa)
ENSACLP00000023814Uncharacterized protein; Belongs to the histone H2A family. (241 aa)
ENSACLP00000023827Uncharacterized protein. (773 aa)
ENSACLP00000023958annotation not available (108 aa)
ENSACLP00000023998annotation not available (93 aa)
ENSACLP00000024183Histone H2A; Belongs to the histone H2A family. (122 aa)
LOC113035672Histone H2A; Belongs to the histone H2A family. (138 aa)
CBX2Chromobox 2. (533 aa)
ENSACLP00000026173Mitogen-activated protein kinase. (390 aa)
LOC113010915Histone H2B; Belongs to the histone H2B family. (116 aa)
SCML2Scm polycomb group protein like 2. (686 aa)
LOC113027596Chromobox homolog 7b. (258 aa)
LOC113008059Mitogen-activated protein kinase kinase kinase kinase 4. (1487 aa)
LOC113022853MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (412 aa)
ENSACLP00000028690Lysine (K)-specific demethylase 6B, a. (2186 aa)
LOC113020216VEFS-Box domain-containing protein. (741 aa)
cbx2Chromobox homolog 2 (Drosophila Pc class). (526 aa)
map2k4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (426 aa)
LOC113020374Scm polycomb group protein like 2. (681 aa)
LOC113032720Si:dkey-283b15.2. (594 aa)
LOC113028005Mitogen-activated protein kinase kinase 6. (359 aa)
LOC113033077Uncharacterized protein. (1298 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (131 aa)
bmi1Bmi1 polycomb ring finger oncogene 1a. (335 aa)
ENSACLP00000033001Ring finger protein 2. (364 aa)
H3-3BHistone H3.3. (136 aa)
ENSACLP00000033341Protein kinase domain-containing protein. (158 aa)
ENSACLP00000033485TRAF2 and NCK interacting kinase b. (531 aa)
cdk6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (325 aa)
ezh2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (763 aa)
ENSACLP00000034906Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (159 aa)
ENSACLP00000034976Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (127 aa)
LOC113033615Histone H2A; Belongs to the histone H2A family. (129 aa)
ENSACLP00000035755Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (404 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (421 aa)
LOC113011809V-fos FBJ murine osteosarcoma viral oncogene homolog Aa. (380 aa)
MAP2K6Mitogen-activated protein kinase kinase 6. (254 aa)
fosl2Fos-like antigen 2. (353 aa)
ENSACLP00000038872Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (164 aa)
ENSACLP00000039028Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (95 aa)
ENSACLP00000039140Histone H2B; Belongs to the histone H2B family. (132 aa)
ENSACLP00000039196Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
map3k5Mitogen-activated protein kinase kinase kinase 5. (1370 aa)
scmh1SAM domain-containing protein. (780 aa)
LOC113015812Mitogen-activated protein kinase kinase kinase kinase 4. (1500 aa)
LOC113020834Chromobox homolog 4 (Pc class homolog, Drosophila). (616 aa)
LOC113020844Chromobox homolog 8a (Pc class homolog, Drosophila). (342 aa)
LOC113020841Neuronal pentraxin 2a. (449 aa)
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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