46 items (Astatotilapia calliptera) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (253 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
	LOC113023252	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
	fgf5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
	RPS27A	Ribosomal protein S27a. (212 aa)
	LOC113016435	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	ENSACLP00000008280	Cbl-PTB domain-containing protein. (724 aa)
	ANOS1	Anosmin 1. (673 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1205 aa)
	ENSACLP00000009605	Ubiquitin B. (723 aa)
	ENSACLP00000009897	Cbl-PTB domain-containing protein. (451 aa)
	LOC113035561	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
	LOC113009440	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
	LOC113035745	Serine/threonine-protein phosphatase. (309 aa)
	LOC113021014	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
	ENSACLP00000012013	Anosmin 1a. (651 aa)
	fgf10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
	LOC113030103	Uncharacterized protein. (3518 aa)
	LOC113009505	Anosmin 1b. (724 aa)
	FGF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	mknk2	MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (476 aa)
	fgf1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (182 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	LOC113033119	Fibroblast growth factor receptor. (836 aa)
	LOC113013184	Tyrosine-protein kinase. (552 aa)
	grb2	Growth factor receptor-bound protein 2b. (217 aa)
	LOC113036096	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	LOC113025830	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
	fgf17	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	ENSACLP00000029128	Uncharacterized protein. (228 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (950 aa)
	ENSACLP00000029955	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (262 aa)
	FGF6-2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	LOC113024985	Fibroblast growth factor receptor substrate 2b. (525 aa)
	SRC	Tyrosine-protein kinase. (550 aa)
	CBL	Cbl proto-oncogene. (514 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	LOC113033704	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1237 aa)
	LOC113015799	MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (462 aa)
	LOC113016782	Sprouty RTK signaling antagonist 2. (333 aa)
	LOC113031983	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (600 aa)

Your Current Organism:

Astatotilapia calliptera

NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANOS1	ENSACLP00000029128	ENSACLP00000008551	ENSACLP00000029128	Anosmin 1.	Uncharacterized protein.	0.746
ANOS1	ENSACLP00000029955	ENSACLP00000008551	ENSACLP00000029955	Anosmin 1.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.661
ANOS1	FGF6	ENSACLP00000008551	ENSACLP00000016108	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.409
ANOS1	FGF6-2	ENSACLP00000008551	ENSACLP00000029977	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.409
ANOS1	LOC113009440	ENSACLP00000008551	ENSACLP00000010438	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.602
ANOS1	LOC113016435	ENSACLP00000008551	ENSACLP00000004929	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.479
ANOS1	LOC113023252	ENSACLP00000008551	ENSACLP00000000196	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.608
ANOS1	LOC113025830	ENSACLP00000008551	ENSACLP00000028651	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.479
ANOS1	LOC113033119	ENSACLP00000008551	ENSACLP00000023821	Anosmin 1.	Fibroblast growth factor receptor.	0.746
ANOS1	LOC113033704	ENSACLP00000008551	ENSACLP00000034581	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.608
ANOS1	LOC113035561	ENSACLP00000008551	ENSACLP00000009951	Anosmin 1.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.608
ANOS1	fgf1	ENSACLP00000008551	ENSACLP00000016836	Anosmin 1.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.608
ANOS1	fgf10	ENSACLP00000008551	ENSACLP00000013832	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.479
ANOS1	fgf17	ENSACLP00000008551	ENSACLP00000028782	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.585
ANOS1	fgf2	ENSACLP00000008551	ENSACLP00000020723	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.580
ANOS1	fgf4	ENSACLP00000008551	ENSACLP00000000005	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.602
ANOS1	fgf5	ENSACLP00000008551	ENSACLP00000003046	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.593
ANOS1	fgf8	ENSACLP00000008551	ENSACLP00000006943	Anosmin 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.747
CBL	ENSACLP00000009605	ENSACLP00000031967	ENSACLP00000009605	Cbl proto-oncogene.	Ubiquitin B.	0.803
CBL	ENSACLP00000029128	ENSACLP00000031967	ENSACLP00000029128	Cbl proto-oncogene.	Uncharacterized protein.	0.595