STRINGSTRING
fgf4 fgf4 fgf19 fgf19 LOC113023252 LOC113023252 RPS27A RPS27A fgf8 fgf8 ENSACLP00000008280 ENSACLP00000008280 fgf16 fgf16 ppp2cb ppp2cb fndc3b fndc3b ENSACLP00000009605 ENSACLP00000009605 ENSACLP00000009897 ENSACLP00000009897 LOC113035561 LOC113035561 LOC113009440 LOC113009440 LOC113035745 LOC113035745 LOC113021014 LOC113021014 LOC113030103 LOC113030103 mapk1 mapk1 ENSACLP00000015303 ENSACLP00000015303 FGF6 FGF6 mknk2 mknk2 fgf1 fgf1 LOC113031338 LOC113031338 fgf2 fgf2 ppp2ca ppp2ca LOC113013184 LOC113013184 grb2 grb2 LOC113036096 LOC113036096 fgf17 fgf17 cbl cbl ENSACLP00000029955 ENSACLP00000029955 FGF6-2 FGF6-2 LOC113024985 LOC113024985 uba52 uba52 SRC SRC CBL CBL LOC113033704 LOC113033704 fndc3a fndc3a LOC113015799 LOC113015799 LOC113016782 LOC113016782 LOC113031983 LOC113031983
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC113023252Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
RPS27ARibosomal protein S27a. (212 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSACLP00000008280Cbl-PTB domain-containing protein. (724 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
fndc3bFibronectin type III domain containing 3Ba. (1205 aa)
ENSACLP00000009605Ubiquitin B. (723 aa)
ENSACLP00000009897Cbl-PTB domain-containing protein. (451 aa)
LOC113035561Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
LOC113009440Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (190 aa)
LOC113035745Serine/threonine-protein phosphatase. (309 aa)
LOC113021014Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
LOC113030103Uncharacterized protein. (3518 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
ENSACLP00000015303Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (228 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
mknk2MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (476 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (182 aa)
LOC113031338Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
LOC113013184Tyrosine-protein kinase. (552 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC113036096Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (950 aa)
ENSACLP00000029955Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (262 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC113024985Fibroblast growth factor receptor substrate 2b. (525 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
SRCTyrosine-protein kinase. (550 aa)
CBLCbl proto-oncogene. (514 aa)
LOC113033704Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
fndc3aFibronectin type III domain containing 3A. (1237 aa)
LOC113015799MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (462 aa)
LOC113016782Sprouty RTK signaling antagonist 2. (333 aa)
LOC113031983Cbl proto-oncogene C, E3 ubiquitin protein ligase. (600 aa)
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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