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mad1l1 | Mitotic arrest deficient 1 like 1. (720 aa) | ||||
gsk3b | Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (425 aa) | ||||
PLK1 | Serine/threonine-protein kinase PLK. (582 aa) | ||||
ENSACLP00000002048 | Zinc finger protein 652. (469 aa) | ||||
anapc7 | Anaphase promoting complex subunit 7. (565 aa) | ||||
ccne1 | Cyclin E1; Belongs to the cyclin family. (428 aa) | ||||
espl1 | Extra spindle pole bodies like 1, separase. (2169 aa) | ||||
LOC113020369 | Cyclin-dependent kinase 21; Belongs to the protein kinase superfamily. (300 aa) | ||||
ENSACLP00000006245 | Protein kinase domain-containing protein. (194 aa) | ||||
ENSACLP00000006066 | BUB3 mitotic checkpoint protein. (324 aa) | ||||
ENSACLP00000005893 | SCD domain-containing protein. (1191 aa) | ||||
mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (740 aa) | ||||
cdk2 | Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) | ||||
LOC113036694 | 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2; Belongs to the 14-3-3 family. (247 aa) | ||||
cdk7 | Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa) | ||||
LOC113009452 | Uncharacterized protein. (178 aa) | ||||
LOC113009063 | Uncharacterized protein. (181 aa) | ||||
cdk4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (306 aa) | ||||
bub1b | BUB1 mitotic checkpoint serine/threonine kinase Bb. (426 aa) | ||||
ENSACLP00000004744 | Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (414 aa) | ||||
ccna1 | Cyclin A1; Belongs to the cyclin family. (398 aa) | ||||
LOC113037131 | Ribosomal_L7Ae domain-containing protein. (166 aa) | ||||
ENSACLP00000004131 | TAN domain-containing protein. (177 aa) | ||||
LOC113006604 | Growth arrest and DNA damage inducible beta. (161 aa) | ||||
ENSACLP00000004087 | Uncharacterized protein. (139 aa) | ||||
GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) | ||||
LOC113032810 | Cyclin E2; Belongs to the cyclin family. (391 aa) | ||||
FZR1 | Fizzy/cell division cycle 20 related 1a. (496 aa) | ||||
LOC113033248 | Mothers against decapentaplegic homolog. (489 aa) | ||||
tfdp1 | Transcription factor. (413 aa) | ||||
LOC113035402 | Cyclin B2; Belongs to the cyclin family. (386 aa) | ||||
ENSACLP00000035671 | Cell division cycle 20 homolog. (492 aa) | ||||
ttk | Ttk protein kinase. (1006 aa) | ||||
ENSACLP00000034976 | Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (127 aa) | ||||
ENSACLP00000034906 | Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (159 aa) | ||||
LOC113019977 | Cyclin Dx; Belongs to the cyclin family. (317 aa) | ||||
LOC113010290 | Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (368 aa) | ||||
ENSACLP00000034034 | Uncharacterized protein. (545 aa) | ||||
cul1 | Cullin 1b; Belongs to the cullin family. (776 aa) | ||||
cdk6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (325 aa) | ||||
LOC113030401 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family. (255 aa) | ||||
LOC113022485 | Cyclin-dependent kinase inhibitor 1A. (165 aa) | ||||
LOC113022479 | Cyclin D3; Belongs to the cyclin family. (317 aa) | ||||
wee1 | Wee1-like protein kinase. (622 aa) | ||||
LOC113016698 | WD_REPEATS_REGION domain-containing protein. (518 aa) | ||||
LOC113026355 | Structural maintenance of chromosomes protein. (1245 aa) | ||||
LOC113025000 | Retinoblastoma-like 2 (p130). (1098 aa) | ||||
orc1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (899 aa) | ||||
TMEM82 | Transmembrane protein 82. (344 aa) | ||||
CDKN2A | Cyclin dependent kinase inhibitor 2A. (131 aa) | ||||
cdc14a | Cell division cycle 14Ab. (674 aa) | ||||
ENSACLP00000030513 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (469 aa) | ||||
ccnb3 | Cyclin B3; Belongs to the cyclin family. (431 aa) | ||||
LOC113009062 | Cyclin D2, b; Belongs to the cyclin family. (294 aa) | ||||
orc5 | Origin recognition complex, subunit 5. (450 aa) | ||||
HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (484 aa) | ||||
HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (489 aa) | ||||
ENSACLP00000028325 | Cell division cycle 26 homolog. (87 aa) | ||||
LOC113036502 | Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa) | ||||
rad21 | RAD21 cohesin complex component a. (635 aa) | ||||
LOC113012094 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b; Belongs to the 14-3-3 family. (247 aa) | ||||
hdac8 | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (387 aa) | ||||
ENSACLP00000027823 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (819 aa) | ||||
mcm5 | DNA helicase; Belongs to the MCM family. (737 aa) | ||||
LOC113027597 | E1A binding protein p300 a. (2787 aa) | ||||
mcm4 | DNA helicase; Belongs to the MCM family. (860 aa) | ||||
orc2 | Uncharacterized protein. (576 aa) | ||||
cdc23 | CDC23 (cell division cycle 23, yeast, homolog). (595 aa) | ||||
ENSACLP00000026364 | Uncharacterized protein. (371 aa) | ||||
LOC113007307 | Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa) | ||||
ENSACLP00000025961 | Uncharacterized protein. (159 aa) | ||||
LOC113033624 | Mothers against decapentaplegic homolog. (510 aa) | ||||
mcm6 | DNA helicase; Belongs to the MCM family. (828 aa) | ||||
dbf4 | DBF4 zinc finger. (637 aa) | ||||
anapc5 | Anaphase promoting complex subunit 5. (771 aa) | ||||
anapc4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (807 aa) | ||||
orc3 | Origin recognition complex, subunit 3. (720 aa) | ||||
ENSACLP00000025268 | Retinoblastoma-like 1 (p107). (1067 aa) | ||||
LOC113014376 | Mothers against decapentaplegic homolog. (607 aa) | ||||
mad2l2 | Mitotic arrest deficient 2 like 2. (210 aa) | ||||
tmem82 | Transmembrane protein 82. (348 aa) | ||||
snapin | SNAP associated protein. (156 aa) | ||||
LOC113021870 | Si:dkey-222f2.1; Belongs to the intermediate filament family. (451 aa) | ||||
fam126b | Zgc:158316. (615 aa) | ||||
cdc6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (602 aa) | ||||
ENSACLP00000024253 | Zinc finger and BTB domain containing 17. (775 aa) | ||||
CCND1 | Cyclin D1; Belongs to the cyclin family. (293 aa) | ||||
SMAD3 | Mothers against decapentaplegic homolog. (425 aa) | ||||
ENSACLP00000023092 | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4053 aa) | ||||
zbtb10 | Zinc finger and BTB domain containing 10. (740 aa) | ||||
ENSACLP00000002506 | Uncharacterized protein. (179 aa) | ||||
LOC113036202 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (277 aa) | ||||
e2f2 | Si:ch211-160f23.5. (448 aa) | ||||
ENSACLP00000022602 | Mothers against decapentaplegic homolog. (494 aa) | ||||
smad3 | Mothers against decapentaplegic homolog. (425 aa) | ||||
ENSACLP00000021745 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa) | ||||
ENSACLP00000021730 | Uncharacterized protein. (436 aa) | ||||
LOC113025730 | Mothers against decapentaplegic homolog. (503 aa) | ||||
skp1 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa) | ||||
gadd45g | Growth arrest and DNA-damage-inducible, gamma a. (159 aa) | ||||
LOC113014748 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Belongs to the 14-3-3 family. (263 aa) | ||||
e2f1 | E2F transcription factor 1. (454 aa) | ||||
LOC113021131 | E1A binding protein p300 b. (2771 aa) | ||||
cdc27 | Cell division cycle 27. (807 aa) | ||||
rbx1 | Ring-box 1, E3 ubiquitin protein ligase. (107 aa) | ||||
LOC113033065 | Uncharacterized protein. (589 aa) | ||||
ENSACLP00000020481 | E2F_CC-MB domain-containing protein. (233 aa) | ||||
E2F3 | E2F transcription factor 3. (445 aa) | ||||
LOC113009944 | Fizzy/cell division cycle 20 related 1b. (531 aa) | ||||
LOC113014899 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) | ||||
cdkn1b | Cyclin-dependent kinase inhibitor 1Bb. (184 aa) | ||||
cdc16 | Cell division cycle 16 homolog (S. cerevisiae). (619 aa) | ||||
GADD45A | Growth arrest and DNA-damage-inducible, alpha, b. (177 aa) | ||||
ENSACLP00000040195 | Zinc finger and BTB domain containing 47b. (648 aa) | ||||
ccnb1 | Cyclin B1; Belongs to the cyclin family. (399 aa) | ||||
LOC113020749 | CREB binding protein b. (2474 aa) | ||||
LOC113027366 | Ribosomal_L7Ae domain-containing protein. (157 aa) | ||||
LOC113027367 | Growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1. (154 aa) | ||||
LOC113011971 | Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa) | ||||
YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b; Belongs to the 14-3-3 family. (244 aa) | ||||
ENSACLP00000036875 | Stromal antigen 2b. (1278 aa) | ||||
ENSACLP00000036881 | CREB binding protein a. (2436 aa) | ||||
LOC113025941 | Mothers against decapentaplegic homolog. (472 aa) | ||||
smc3 | Structural maintenance of chromosomes protein. (1217 aa) | ||||
cntd2 | Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (406 aa) | ||||
ENSACLP00000037904 | Anaphase promoting complex subunit 1. (1883 aa) | ||||
LOC113027446 | Cyclin-dependent kinase inhibitor 1Cb. (208 aa) | ||||
zbtb46 | Zinc finger and BTB domain containing 46. (861 aa) | ||||
ENSACLP00000038411 | Cell division cycle 20 homolog. (361 aa) | ||||
LOC113008396 | Si:ch211-269e2.1. (1185 aa) | ||||
cdc25b | Rhodanese domain-containing protein. (571 aa) | ||||
abl1 | Tyrosine-protein kinase. (1104 aa) | ||||
ap5s1 | Adaptor related protein complex 5 subunit sigma 1. (200 aa) | ||||
ENSACLP00000019391 | Cyclin-dependent kinase 20. (531 aa) | ||||
LOC113031225 | Cyclin A2; Belongs to the cyclin family. (440 aa) | ||||
rb1 | Retinoblastoma 1. (912 aa) | ||||
TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa) | ||||
mdm2 | MDM2 proto-oncogene. (523 aa) | ||||
ENSACLP00000018094 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (211 aa) | ||||
ENSACLP00000018067 | BUB1 N-terminal domain-containing protein. (85 aa) | ||||
anapc10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (186 aa) | ||||
skp2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (416 aa) | ||||
LOC113032586 | Uncharacterized protein. (799 aa) | ||||
LOC113031082 | Stromal antigen 2a. (1276 aa) | ||||
LOC113010824 | E2F transcription factor 5. (385 aa) | ||||
pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa) | ||||
anapc13 | Anaphase promoting complex subunit 13. (74 aa) | ||||
ENSACLP00000016742 | E2F transcription factor 4. (373 aa) | ||||
cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae). (568 aa) | ||||
LOC113015757 | Uncharacterized protein. (156 aa) | ||||
LOC113027151 | Cyclin D2, a; Belongs to the cyclin family. (297 aa) | ||||
pkmyt1 | Protein kinase, membrane associated tyrosine/threonine 1. (583 aa) | ||||
ENSACLP00000015199 | APC11 anaphase promoting complex subunit 11 homolog (yeast). (94 aa) | ||||
GADD45B-2 | Growth arrest and DNA damage inducible beta. (214 aa) | ||||
LOC113031427 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa) | ||||
chek2 | Checkpoint kinase 2. (523 aa) | ||||
cdc7 | Cell division cycle 7 homolog (S. cerevisiae). (611 aa) | ||||
LOC113011288 | Growth arrest and DNA-damage-inducible, alpha, a. (163 aa) | ||||
mcm3 | DNA helicase; Belongs to the MCM family. (811 aa) | ||||
LOC113027124 | Wee1-like protein kinase. (547 aa) | ||||
ENSACLP00000012049 | Myelocytomatosis oncogene homolog. (336 aa) | ||||
cdkn2d | Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa) | ||||
ENSACLP00000011103 | Transforming growth factor beta; Belongs to the TGF-beta family. (403 aa) | ||||
LOC113022176 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (244 aa) | ||||
snph | Syntaphilin b. (877 aa) | ||||
mcm2 | DNA helicase; Belongs to the MCM family. (886 aa) | ||||
stag1 | Stromal antigen 1a. (1266 aa) | ||||
ENSACLP00000008418 | MAD2 mitotic arrest deficient-like 1 (yeast). (205 aa) | ||||
ENSACLP00000008410 | annotation not available (228 aa) | ||||
ENSACLP00000008384 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2524 aa) | ||||
ENSACLP00000008361 | MAD2 mitotic arrest deficient-like 1 (yeast). (215 aa) | ||||
ccnh | Cyclin H; Belongs to the cyclin family. (350 aa) | ||||
LOC113030590 | 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1; Belongs to the 14-3-3 family. (247 aa) | ||||
ENSACLP00000007272 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (276 aa) | ||||
LOC113023392 | E2F_TDP domain-containing protein. (307 aa) | ||||
smc1a | Structural maintenance of chromosomes protein. (1231 aa) | ||||
LOC113018712 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (384 aa) |