STRINGSTRING
mapk1 mapk1 LOC113020749 LOC113020749 LOC113027365 LOC113027365 LOC113029118 LOC113029118 grem1 grem1 LOC113006633 LOC113006633 ENSACLP00000039006 ENSACLP00000039006 bmp2 bmp2 LOC113030367 LOC113030367 LOC113012562 LOC113012562 smad1 smad1 LOC113025941 LOC113025941 LOC113022549 LOC113022549 bmpr2 bmpr2 LOC113034265 LOC113034265 ENSACLP00000036881 ENSACLP00000036881 fmod fmod LOC113011971 LOC113011971 ENSACLP00000036110 ENSACLP00000036110 ENSACLP00000035784 ENSACLP00000035784 LOC113032230 LOC113032230 LOC113032604 LOC113032604 LOC113032605 LOC113032605 LOC113032603 LOC113032603 ENSACLP00000035047 ENSACLP00000035047 ENSACLP00000035046 ENSACLP00000035046 LOC113032318 LOC113032318 LOC113027337 LOC113027337 ENSACLP00000034721 ENSACLP00000034721 ENSACLP00000034678 ENSACLP00000034678 LOC113032212 LOC113032212 ENSACLP00000034495 ENSACLP00000034495 LOC113032194 LOC113032194 LOC113010290 LOC113010290 ENSACLP00000034121 ENSACLP00000034121 cul1 cul1 ENSACLP00000033904 ENSACLP00000033904 LOC113007123 LOC113007123 LOC113008224 LOC113008224 LOC113009045 LOC113009045 LOC113033226 LOC113033226 LOC113022007 LOC113022007 NBL1 NBL1 LOC113027667 LOC113027667 rgma rgma CDKN2A CDKN2A LOC113022452 LOC113022452 bmp8a bmp8a ENSACLP00000030856 ENSACLP00000030856 LOC113031843 LOC113031843 ENSACLP00000029906 ENSACLP00000029906 ENSACLP00000029716 ENSACLP00000029716 bmp6 bmp6 ENSACLP00000029027 ENSACLP00000029027 grem2 grem2 LOC113022850 LOC113022850 ENSACLP00000028772 ENSACLP00000028772 LOC113036502 LOC113036502 INHBC INHBC LOC113027597 LOC113027597 LOC113036096 LOC113036096 sp1 sp1 THSD4 THSD4 LOC113013171 LOC113013171 id2 id2 LOC113021225 LOC113021225 ANKFN1 ANKFN1 ENSACLP00000026236 ENSACLP00000026236 ENSACLP00000026208 ENSACLP00000026208 LOC113007307 LOC113007307 LOC113033624 LOC113033624 ENSACLP00000025583 ENSACLP00000025583 LDAH LDAH LOC113029552 LOC113029552 ENSACLP00000025423 ENSACLP00000025423 FBN1 FBN1 ENSACLP00000025385 ENSACLP00000025385 LOC113011625 LOC113011625 ENSACLP00000025268 ENSACLP00000025268 LOC113036990 LOC113036990 LOC113014376 LOC113014376 snapin snapin LOC113021870 LOC113021870 rock1 rock1 ENSACLP00000024355 ENSACLP00000024355 LOC113029528 LOC113029528 LOC113019522 LOC113019522 SMAD3 SMAD3 ENSACLP00000023924 ENSACLP00000023924 LTBP3 LTBP3 ENSACLP00000023013 ENSACLP00000023013 ENSACLP00000022855 ENSACLP00000022855 LOC113008136 LOC113008136 id3 id3 ENSACLP00000022602 ENSACLP00000022602 pitx1 pitx1 smad6 smad6 smad3 smad3 LOC113014729 LOC113014729 LOC113025742 LOC113025742 LOC113023691 LOC113023691 chrd chrd ACVR2A ACVR2A LOC113025730 LOC113025730 ppp2ca ppp2ca skp1 skp1 LOC113021131 LOC113021131 ENSACLP00000020873 ENSACLP00000020873 rbx1 rbx1 ENSACLP00000020843 ENSACLP00000020843 ACVR1C ACVR1C acvr1 acvr1 ENSACLP00000019899 ENSACLP00000019899 gdf5 gdf5 TGFB3 TGFB3 bmp4 bmp4 LOC113032360 LOC113032360 LOC113009362 LOC113009362 LOC113010824 LOC113010824 ENSACLP00000017098 ENSACLP00000017098 ENSACLP00000016742 ENSACLP00000016742 MATN2 MATN2 ENSACLP00000016104 ENSACLP00000016104 smurf1 smurf1 LOC113012044 LOC113012044 LOC113031642 LOC113031642 ENSACLP00000015433 ENSACLP00000015433 pitx2 pitx2 bambi bambi ENSACLP00000015281 ENSACLP00000015281 LOC113028451 LOC113028451 LOC113007501 LOC113007501 ENSACLP00000014162 ENSACLP00000014162 LOC113013555 LOC113013555 LOC113032577 LOC113032577 ENSACLP00000013398 ENSACLP00000013398 ENSACLP00000012848 ENSACLP00000012848 LOC113010725 LOC113010725 LOC113031657 LOC113031657 ENSACLP00000012049 ENSACLP00000012049 LOC113006385 LOC113006385 LOC113021014 LOC113021014 LOC113023567 LOC113023567 TGFBR2 TGFBR2 ENSACLP00000011103 ENSACLP00000011103 LOC113012962 LOC113012962 LOC113016719 LOC113016719 LOC113035745 LOC113035745 zfyve9 zfyve9 ENSACLP00000009575 ENSACLP00000009575 ppp2cb ppp2cb pknox1 pknox1 LOC113035264 LOC113035264 smad7 smad7 ACVR1B ACVR1B LOC113013569 LOC113013569 LOC113028987 LOC113028987 ENSACLP00000008410 ENSACLP00000008410 LOC113022661 LOC113022661 LOC113022662 LOC113022662 nodal nodal LOC113023392 LOC113023392 LOC113015031 LOC113015031 ENSACLP00000006413 ENSACLP00000006413 LOC113012724 LOC113012724 fstl3 fstl3 ENSACLP00000004744 ENSACLP00000004744 smad9 smad9 LOC113036051 LOC113036051 rgmb rgmb bmpr1a bmpr1a SMURF2 SMURF2 LOC113012818 LOC113012818 GREM1 GREM1 pknox2 pknox2 LOC113033248 LOC113033248 tfdp1 tfdp1 LOC113014962 LOC113014962 ENSACLP00000002714 ENSACLP00000002714 LOC113031943 LOC113031943 LOC113031942 LOC113031942 ltbp2 ltbp2 gdf6 gdf6 ENSACLP00000000119 ENSACLP00000000119
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
LOC113020749CREB binding protein b. (2474 aa)
LOC113027365Uncharacterized protein. (87 aa)
LOC113029118TGFB-induced factor homeobox 1. (307 aa)
grem1Gremlin 1a, DAN family BMP antagonist. (179 aa)
LOC113006633Thrombospondin 1b. (1168 aa)
ENSACLP00000039006Uncharacterized protein. (81 aa)
bmp2Bone morphogenetic protein 2b. (418 aa)
LOC113030367Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (539 aa)
LOC113012562Matrilin 3b. (660 aa)
smad1Mothers against decapentaplegic homolog. (467 aa)
LOC113025941Mothers against decapentaplegic homolog. (472 aa)
LOC113022549Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (500 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1067 aa)
LOC113034265Southpaw. (412 aa)
ENSACLP00000036881CREB binding protein a. (2436 aa)
fmodFibromodulin b. (347 aa)
LOC113011971Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
ENSACLP00000036110Si:dkey-235d18.5. (516 aa)
ENSACLP00000035784Zinc finger, FYVE domain containing 9b. (679 aa)
LOC113032230Growth differentiation factor 6a. (440 aa)
LOC113032604Uncharacterized protein. (86 aa)
LOC113032605Uncharacterized protein. (85 aa)
LOC113032603Uncharacterized protein. (86 aa)
ENSACLP00000035047Uncharacterized protein. (85 aa)
ENSACLP00000035046RGM domain family, member D. (463 aa)
LOC113032318Uncharacterized protein. (86 aa)
LOC113027337Nodal-related 1. (402 aa)
ENSACLP00000034721Zinc finger, FYVE domain containing 16. (1408 aa)
ENSACLP00000034678annotation not available (85 aa)
LOC113032212Uncharacterized protein. (86 aa)
ENSACLP00000034495Uncharacterized protein. (85 aa)
LOC113032194Uncharacterized protein. (86 aa)
LOC113010290Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (368 aa)
ENSACLP00000034121Uncharacterized protein. (83 aa)
cul1Cullin 1b; Belongs to the cullin family. (776 aa)
ENSACLP00000033904Anti-Mullerian hormone. (512 aa)
LOC113007123Matrilin 3a. (486 aa)
LOC113008224Inhibin subunit beta B. (404 aa)
LOC113009045Decorin; May affect the rate of fibrils formation. (358 aa)
LOC113033226Mothers against decapentaplegic homolog. (473 aa)
LOC113022007Ras homolog family member Cb. (193 aa)
NBL1NBL1, DAN family BMP antagonist. (187 aa)
LOC113027667TGF_BETA_2 domain-containing protein. (379 aa)
rgmaRepulsive guidance molecule BMP co-receptor a. (446 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (131 aa)
LOC113022452Ras homolog gene family, member Ab. (195 aa)
bmp8aBone morphogenetic protein 8a. (452 aa)
ENSACLP00000030856Fibrillin 2b. (2678 aa)
LOC113031843PLAC domain-containing protein. (1192 aa)
ENSACLP00000029906Inhibitor of DNA binding 1, HLH protein. (130 aa)
ENSACLP00000029716Noggin; Belongs to the noggin family. (222 aa)
bmp6Bone morphogenetic protein 6; Belongs to the enoyl-CoA hydratase/isomerase family. (601 aa)
ENSACLP00000029027Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (499 aa)
grem2Gremlin 2, DAN family BMP antagonist a. (192 aa)
LOC113022850Bone morphogenetic protein 7a. (425 aa)
ENSACLP00000028772Matrilin 1. (492 aa)
LOC113036502Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
INHBCInhibin subunit beta C. (374 aa)
LOC113027597E1A binding protein p300 a. (2787 aa)
LOC113036096Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
sp1Sp1 transcription factor. (729 aa)
THSD4Thrombospondin type 1 domain containing 4. (971 aa)
LOC113013171Uncharacterized protein. (193 aa)
id2Inhibitor of DNA binding 2a. (136 aa)
LOC113021225E3 ubiquitin-protein ligase. (844 aa)
ANKFN1Ankyrin repeat and fibronectin type III domain containing 1. (425 aa)
ENSACLP00000026236Uncharacterized protein. (387 aa)
ENSACLP00000026208Noggin. (189 aa)
LOC113007307Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
LOC113033624Mothers against decapentaplegic homolog. (510 aa)
ENSACLP00000025583Growth differentiation factor 7. (376 aa)
LDAHLipid droplet associated hydrolase. (352 aa)
LOC113029552Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (515 aa)
ENSACLP00000025423Growth differentiation factor 7. (411 aa)
FBN1Fibrillin 1. (2866 aa)
ENSACLP00000025385Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (524 aa)
LOC113011625Lipid droplet associated hydrolase. (352 aa)
ENSACLP00000025268Retinoblastoma-like 1 (p107). (1067 aa)
LOC113036990Bone morphogenetic protein 16. (504 aa)
LOC113014376Mothers against decapentaplegic homolog. (607 aa)
snapinSNAP associated protein. (156 aa)
LOC113021870Si:dkey-222f2.1; Belongs to the intermediate filament family. (451 aa)
rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1386 aa)
ENSACLP00000024355TGF_BETA_2 domain-containing protein. (383 aa)
LOC113029528Inhibin subunit beta Aa. (450 aa)
LOC113019522Mothers against decapentaplegic homolog. (501 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
ENSACLP00000023924Fibronectin type-III domain-containing protein. (774 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1239 aa)
ENSACLP00000023013Matrilin 4. (645 aa)
ENSACLP00000022855TGF_BETA_2 domain-containing protein. (391 aa)
LOC113008136Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (653 aa)
id3Inhibitor of DNA binding 3. (117 aa)
ENSACLP00000022602Mothers against decapentaplegic homolog. (494 aa)
pitx1Homeobox protein. (315 aa)
smad6Mothers against decapentaplegic homolog. (488 aa)
smad3Mothers against decapentaplegic homolog. (425 aa)
LOC113014729TNF_2 domain-containing protein. (237 aa)
LOC113025742Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (537 aa)
LOC113023691Uncharacterized protein. (334 aa)
chrdChordin; Belongs to the chordin family. (952 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
LOC113025730Mothers against decapentaplegic homolog. (503 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
LOC113021131E1A binding protein p300 b. (2771 aa)
ENSACLP00000020873Uncharacterized protein. (424 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (107 aa)
ENSACLP00000020843PLAC domain-containing protein. (201 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
acvr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (685 aa)
ENSACLP00000019899Neogenin 1b. (1338 aa)
gdf5Growth differentiation factor 5. (477 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
bmp4Bone morphogenetic protein 4. (403 aa)
LOC113032360Hemojuvelin BMP co-receptor. (416 aa)
LOC113009362Uncharacterized protein. (206 aa)
LOC113010824E2F transcription factor 5. (385 aa)
ENSACLP00000017098Uncharacterized protein. (1315 aa)
ENSACLP00000016742E2F transcription factor 4. (373 aa)
MATN2Matrilin 2. (677 aa)
ENSACLP00000016104Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
smurf1E3 ubiquitin-protein ligase. (733 aa)
LOC113012044Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
LOC113031642Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
ENSACLP00000015433Anti-dorsalizing morphogenic protein. (380 aa)
pitx2Homeobox protein. (313 aa)
bambiBMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a. (296 aa)
ENSACLP00000015281Noggin; Belongs to the noggin family. (208 aa)
LOC113028451Uncharacterized protein. (1398 aa)
LOC113007501Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1199 aa)
ENSACLP00000014162Homeobox domain-containing protein. (132 aa)
LOC113013555Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
LOC113032577Inhibitor of DNA binding 4. (141 aa)
ENSACLP00000013398Follistatin a. (319 aa)
ENSACLP00000012848Uncharacterized protein. (193 aa)
LOC113010725Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
LOC113031657Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (627 aa)
ENSACLP00000012049Myelocytomatosis oncogene homolog. (336 aa)
LOC113006385Lefty1. (357 aa)
LOC113021014Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
LOC113023567Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (470 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
ENSACLP00000011103Transforming growth factor beta; Belongs to the TGF-beta family. (403 aa)
LOC113012962Uncharacterized protein. (193 aa)
LOC113016719TGF_BETA_2 domain-containing protein. (391 aa)
LOC113035745Serine/threonine-protein phosphatase. (309 aa)
zfyve9Zinc finger, FYVE domain containing 9a. (1194 aa)
ENSACLP00000009575TNF_2 domain-containing protein. (208 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
pknox1Pbx/knotted 1 homeobox 1.1. (436 aa)
LOC113035264Homeobox protein. (295 aa)
smad7Mothers against decapentaplegic homolog. (376 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
LOC113013569Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
LOC113028987Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
ENSACLP00000008410annotation not available (228 aa)
LOC113022661Zgc:113307. (383 aa)
LOC113022662Fibromodulin a. (348 aa)
nodalNodal-related 2. (386 aa)
LOC113023392E2F_TDP domain-containing protein. (307 aa)
LOC113015031MYCL proto-oncogene, bHLH transcription factor b. (471 aa)
ENSACLP00000006413DCC netrin 1 receptor. (1537 aa)
LOC113012724MYCL proto-oncogene, bHLH transcription factor a. (369 aa)
fstl3Follistatin-like 3 (secreted glycoprotein). (250 aa)
ENSACLP00000004744Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (414 aa)
smad9Mothers against decapentaplegic homolog. (468 aa)
LOC113036051Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (503 aa)
rgmbRepulsive guidance molecule BMP co-receptor b. (474 aa)
bmpr1aReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (529 aa)
SMURF2E3 ubiquitin-protein ligase. (776 aa)
LOC113012818Uncharacterized protein. (193 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (137 aa)
pknox2Pbx/knotted 1 homeobox 2. (488 aa)
LOC113033248Mothers against decapentaplegic homolog. (489 aa)
tfdp1Transcription factor. (413 aa)
LOC113014962Upstream transcription factor 2, c-fos interacting. (327 aa)
ENSACLP00000002714Thrombospondin 1a. (1126 aa)
LOC113031943BHLH domain-containing protein. (330 aa)
LOC113031942Uncharacterized protein. (90 aa)
ltbp2Uncharacterized protein. (2080 aa)
gdf6Growth differentiation factor 6b. (436 aa)
ENSACLP00000000119Integrator complex subunit 8. (930 aa)
Your Current Organism:
Astatotilapia calliptera
NCBI taxonomy Id: 8154
Other names: A. calliptera, Ctenochromis callipterus, Haplochromis calliptera, Haplochromis callipterus, eastern happy
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