(33 nodes) Positive regulation of phosphatidylinositol 3-kinase signaling network (Perca flavescens)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	A0A484DBU7	Ig-like domain-containing protein. (451 aa)
	A0A484C472	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (896 aa)
	A0A484C4U4	Decorin; May affect the rate of fibrils formation. (374 aa)
	A0A484CAQ7	DBB domain-containing protein. (851 aa)
	A0A484CC43	Deacetylase sirtuin-type domain-containing protein. (722 aa)
	A0A484CD70	SERPIN domain-containing protein; Belongs to the serpin family. (465 aa)
	A0A484CDM4	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (984 aa)
	A0A484CFX7	G_PROTEIN_RECEP_F1_2 domain-containing protein. (439 aa)
	A0A484CFZ4	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (512 aa)
	A0A484CH91	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (228 aa)
	A0A484CJ28	Uncharacterized protein. (959 aa)
	A0A484CJN1	Uncharacterized protein. (309 aa)
	A0A484CJY7	Tyrosine-protein kinase receptor. (784 aa)
	A0A484CNW2	Gla domain-containing protein. (110 aa)
	A0A484CPJ2	Uncharacterized protein. (313 aa)
	A0A484CV05	Olfactomedin-like domain-containing protein. (439 aa)
	A0A484CX60	Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
	A0A484CYL5	HECT domain-containing protein. (865 aa)
	A0A484CYY4	Olfactomedin-like domain-containing protein. (485 aa)
	A0A484CZV8	Uncharacterized protein. (239 aa)
	A0A484D1G9	Tyrosine-protein kinase receptor. (547 aa)
	A0A484D1R2	Uncharacterized protein. (139 aa)
	A0A484D1T3	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (940 aa)
	A0A484D2I0	Uncharacterized protein. (3476 aa)
	A0A484D3K6	Uncharacterized protein. (342 aa)
	A0A484D5X1	Uncharacterized protein. (506 aa)
	A0A484D7E5	Tyrosine-protein kinase receptor. (797 aa)
	A0A484D9H3	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	A0A484DBP6	Tyrosine-protein kinase receptor. (384 aa)
	A0A484DDU5	Homeobox domain-containing protein. (205 aa)
	A0A484DJT7	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (573 aa)
	A0A484DKK5	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (199 aa)
	A0A484DN87	Tyrosine-protein kinase receptor. (814 aa)

Your Current Organism:

Perca flavescens

NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A484C472	A0A484CYL5	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.	HECT domain-containing protein.	0.845
A0A484C4U4	A0A484CDM4	Decorin; May affect the rate of fibrils formation.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.544
A0A484C4U4	A0A484CNW2	Decorin; May affect the rate of fibrils formation.	Gla domain-containing protein.	0.428
A0A484C4U4	A0A484CX60	Decorin; May affect the rate of fibrils formation.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.902
A0A484C4U4	A0A484D1T3	Decorin; May affect the rate of fibrils formation.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.	0.544
A0A484C4U4	A0A484D9H3	Decorin; May affect the rate of fibrils formation.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.902
A0A484CC43	A0A484D5X1	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein.	0.600
A0A484CD70	A0A484CFX7	SERPIN domain-containing protein; Belongs to the serpin family.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.865
A0A484CD70	A0A484CNW2	SERPIN domain-containing protein; Belongs to the serpin family.	Gla domain-containing protein.	0.809
A0A484CDM4	A0A484C4U4	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Decorin; May affect the rate of fibrils formation.	0.544
A0A484CDM4	A0A484CJY7	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase receptor.	0.549
A0A484CDM4	A0A484D1G9	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase receptor.	0.549
A0A484CDM4	A0A484D1R2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.549
A0A484CDM4	A0A484D7E5	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase receptor.	0.549
A0A484CDM4	A0A484DBP6	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase receptor.	0.549
A0A484CDM4	A0A484DBU7	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Ig-like domain-containing protein.	0.549
A0A484CDM4	A0A484DN87	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase receptor.	0.549
A0A484CFX7	A0A484CD70	G_PROTEIN_RECEP_F1_2 domain-containing protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.865
A0A484CFX7	A0A484CNW2	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Gla domain-containing protein.	0.992
A0A484CFZ4	A0A484CH91	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.907