(71 nodes) Hedgehog signaling pathway network (Perca flavescens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A484D0P1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (449 aa)
	A0A484BYY3	Uncharacterized protein. (174 aa)
	A0A484BZ84	Uncharacterized protein; Belongs to the cyclin family. (294 aa)
	A0A484BZD0	Tetraspanin. (283 aa)
	A0A484BZF0	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (817 aa)
	A0A484C0P8	Uncharacterized protein. (1080 aa)
	A0A484C159	CULLIN_2 domain-containing protein; Belongs to the cullin family. (776 aa)
	A0A484C1H4	Uncharacterized protein; Belongs to the LIMR family. (492 aa)
	A0A484C1I7	Uncharacterized protein. (1632 aa)
	A0A484C1J4	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (413 aa)
	A0A484C232	Uncharacterized protein. (245 aa)
	A0A484C2D0	Uncharacterized protein. (374 aa)
	A0A484C2V7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
	A0A484C3B4	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (457 aa)
	A0A484C3H3	Uncharacterized protein. (1172 aa)
	A0A484C538	Uncharacterized protein. (1374 aa)
	A0A484C829	Uncharacterized protein. (167 aa)
	A0A484C8E6	Arrestin_C domain-containing protein. (410 aa)
	A0A484C8K3	Uncharacterized protein. (1376 aa)
	A0A484CAF9	Uncharacterized protein. (4618 aa)
	A0A484CCJ0	Uncharacterized protein. (370 aa)
	A0A484CD89	Uncharacterized protein. (874 aa)
	A0A484CEV7	Uncharacterized protein. (2974 aa)
	A0A484CFB8	Uncharacterized protein. (258 aa)
	A0A484CGM9	Uncharacterized protein. (167 aa)
	A0A484CGZ6	E3 ubiquitin-protein ligase. (729 aa)
	A0A484CGZ7	Uncharacterized protein. (410 aa)
	A0A484CHP7	RING-type domain-containing protein. (549 aa)
	A0A484CIA9	Uncharacterized protein. (124 aa)
	A0A484CKS5	E3 ubiquitin-protein ligase. (774 aa)
	A0A484CL27	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (417 aa)
	A0A484CN07	Uncharacterized protein; Belongs to the cyclin family. (318 aa)
	A0A484CNE1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (404 aa)
	A0A484CNI8	CULLIN_2 domain-containing protein; Belongs to the cullin family. (766 aa)
	A0A484CNZ3	Arrestin_C domain-containing protein. (416 aa)
	A0A484CPC8	Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
	A0A484CPE5	Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
	A0A484CR60	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (413 aa)
	A0A484CS26	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (597 aa)
	A0A484CSB9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (431 aa)
	A0A484CT15	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (425 aa)
	A0A484CTM9	BH4_2 domain-containing protein. (228 aa)
	A0A484CTU5	SSD domain-containing protein. (1484 aa)
	A0A484CVF5	Uncharacterized protein. (4746 aa)
	A0A484CVI7	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (446 aa)
	A0A484CVV5	Uncharacterized protein. (392 aa)
	A0A484CW42	Uncharacterized protein. (1494 aa)
	A0A484CXG9	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (704 aa)
	A0A484CXS4	Uncharacterized protein. (566 aa)
	A0A484CY36	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (353 aa)
	A0A484D0B7	Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
	A0A484DQN2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
	A0A484DPR8	Uncharacterized protein. (1802 aa)
	A0A484DNM9	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1356 aa)
	A0A484DMY5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (461 aa)
	A0A484DM06	EGF-like domain-containing protein. (702 aa)
	A0A484DLC0	E3 ubiquitin-protein ligase. (760 aa)
	A0A484DL95	Arrestin_C domain-containing protein. (418 aa)
	A0A484DL29	Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
	A0A484DIP0	CULLIN_2 domain-containing protein; Belongs to the cullin family. (767 aa)
	A0A484DFY8	Uncharacterized protein. (1388 aa)
	A0A484DFR1	Uncharacterized protein. (964 aa)
	A0A484DEJ0	Uncharacterized protein. (1486 aa)
	A0A484DCW1	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1583 aa)
	A0A484DBS7	SSD domain-containing protein. (1541 aa)
	A0A484DBE4	Uncharacterized protein. (1380 aa)
	A0A484D7W0	Uncharacterized protein. (2886 aa)
	A0A484D5D4	Uncharacterized protein; Belongs to the LIMR family. (493 aa)
	A0A484D5B3	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (460 aa)
	A0A484D1G7	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (296 aa)
	A0A484D197	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (298 aa)

Your Current Organism:

Perca flavescens

NCBI taxonomy Id: 8167
Other names: Morone flavescens, P. flavescens, yellow perch

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A484BYY3	A0A484BZF0	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.774
A0A484BYY3	A0A484C159	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.876
A0A484BYY3	A0A484C1I7	Uncharacterized protein.	Uncharacterized protein.	0.811
A0A484BYY3	A0A484C1J4	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.491
A0A484BYY3	A0A484C2D0	Uncharacterized protein.	Uncharacterized protein.	0.901
A0A484BYY3	A0A484C2V7	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.618
A0A484BYY3	A0A484C3B4	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.430
A0A484BYY3	A0A484C3H3	Uncharacterized protein.	Uncharacterized protein.	0.499
A0A484BYY3	A0A484C8E6	Uncharacterized protein.	Arrestin_C domain-containing protein.	0.629
A0A484BYY3	A0A484CGZ7	Uncharacterized protein.	Uncharacterized protein.	0.905
A0A484BYY3	A0A484CL27	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.618
A0A484BYY3	A0A484CNE1	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.618
A0A484BYY3	A0A484CNI8	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.778
A0A484BYY3	A0A484CNZ3	Uncharacterized protein.	Arrestin_C domain-containing protein.	0.629
A0A484BYY3	A0A484CPC8	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.683
A0A484BYY3	A0A484CPE5	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.860
A0A484BYY3	A0A484CR60	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.491
A0A484BYY3	A0A484CSB9	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.517
A0A484BYY3	A0A484CT15	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.656
A0A484BYY3	A0A484CTU5	Uncharacterized protein.	SSD domain-containing protein.	0.686