(45 nodes) Negative regulation of transforming growth factor beta receptor signaling pathway network (Sparus aurata)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC115570847	WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2-like. (576 aa)
	LOC115582810	Caveolin-2-like. (188 aa)
	CAV3	Caveolin 3. (185 aa)
	LOC115579700	Mothers against decapentaplegic homolog 6-like. (506 aa)
	lemd3	LEM domain containing 3. (859 aa)
	sirt1	Sirtuin 1. (697 aa)
	tdp2	tyrosyl-DNA phosphodiesterase 2. (362 aa)
	ENSSAUP00010009049	Si:ch211-267e7.3. (468 aa)
	glg1	Golgi glycoprotein 1. (1167 aa)
	LOC115585331	Caveolin-2-like. (212 aa)
	pin1	Peptidylprolyl cis/trans isomerase, NIMA-interacting 1. (156 aa)
	ENSSAUP00010011158	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (594 aa)
	LOC115574096	Disintegrin and metalloproteinase domain-containing protein 17-like. (871 aa)
	LOC115582887	Caveolin-2-like. (166 aa)
	nrros	Negative regulator of reactive oxygen species. (684 aa)
	LOC115583431	Protein TMEPAI-like. (326 aa)
	spry1	Sprouty RTK signaling antagonist 1. (362 aa)
	LOC115574825	WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2-like. (578 aa)
	ENSSAUP00010019818	Heat shock protein 5. (662 aa)
	ldlrad4	Low density lipoprotein receptor class A domain containing 4. (323 aa)
	strap	Serine/threonine kinase receptor associated protein. (341 aa)
	LOC115594527	Protein FAM89A-like. (181 aa)
	smad6	SMAD family member 6. (491 aa)
	ENSSAUP00010028834	Elastin microfibril interfacer 1b. (1059 aa)
	LOC115580273	Golgi apparatus protein 1-like. (1209 aa)
	smad7	SMAD family member 7. (376 aa)
	LOC115583639	Ski oncogene-like. (695 aa)
	lingo3	Leucine rich repeat and Ig domain containing 3. (610 aa)
	LOC115569961	Cell death activator CIDE-A-like. (215 aa)
	ENSSAUP00010040816	Elastin microfibril interfacer 1a. (993 aa)
	znf451	Zinc finger protein 451. (865 aa)
	snx25	Sorting nexin 25. (976 aa)
	LOC115572277	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3. (622 aa)
	ENSSAUP00010046739	ADAMTS-like 2. (924 aa)
	ENSSAUP00010046907	Si:ch211-263k4.2. (1405 aa)
	ENSSAUP00010051938	annotation not available (476 aa)
	spred3	Sprouty related EVH1 domain containing 3. (520 aa)
	bcl9l	BCL9 like. (1529 aa)
	ski	SKI proto-oncogene. (728 aa)
	bambi	BMP and activin membrane bound inhibitor. (262 aa)
	pbld	Phenazine biosynthesis like protein domain containing. (325 aa)
	LOC115578889	Serine protease HTRA3-like. (489 aa)
	LOC115566422	Disintegrin and metalloproteinase domain-containing protein 17-like. (863 aa)
	spry2	Sprouty RTK signaling antagonist 2. (335 aa)
	skil	SKI like proto-oncogene. (773 aa)

Your Current Organism:

Sparus aurata

NCBI taxonomy Id: 8175
Other names: Aurata aurata, S. aurata, Sparus auratus, gilthead bream, gilthead seabream, silver seabream

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSAUP00010019818	sirt1	ENSSAUP00010019818	ENSSAUP00010004232	Heat shock protein 5.	Sirtuin 1.	0.508
ENSSAUP00010046907	LOC115569961	ENSSAUP00010046907	ENSSAUP00010040523	Si:ch211-263k4.2.	Cell death activator CIDE-A-like.	0.520
ENSSAUP00010046907	sirt1	ENSSAUP00010046907	ENSSAUP00010004232	Si:ch211-263k4.2.	Sirtuin 1.	0.400
LOC115569961	ENSSAUP00010046907	ENSSAUP00010040523	ENSSAUP00010046907	Cell death activator CIDE-A-like.	Si:ch211-263k4.2.	0.520
LOC115579700	LOC115583431	ENSSAUP00010002602	ENSSAUP00010016624	Mothers against decapentaplegic homolog 6-like.	Protein TMEPAI-like.	0.481
LOC115579700	LOC115583639	ENSSAUP00010002602	ENSSAUP00010034264	Mothers against decapentaplegic homolog 6-like.	Ski oncogene-like.	0.581
LOC115579700	bambi	ENSSAUP00010002602	ENSSAUP00010063325	Mothers against decapentaplegic homolog 6-like.	BMP and activin membrane bound inhibitor.	0.782
LOC115579700	ldlrad4	ENSSAUP00010002602	ENSSAUP00010020369	Mothers against decapentaplegic homolog 6-like.	Low density lipoprotein receptor class A domain containing 4.	0.481
LOC115579700	lemd3	ENSSAUP00010002602	ENSSAUP00010002907	Mothers against decapentaplegic homolog 6-like.	LEM domain containing 3.	0.590
LOC115579700	ski	ENSSAUP00010002602	ENSSAUP00010055746	Mothers against decapentaplegic homolog 6-like.	SKI proto-oncogene.	0.593
LOC115579700	skil	ENSSAUP00010002602	ENSSAUP00010068924	Mothers against decapentaplegic homolog 6-like.	SKI like proto-oncogene.	0.639
LOC115579700	smad7	ENSSAUP00010002602	ENSSAUP00010031842	Mothers against decapentaplegic homolog 6-like.	SMAD family member 7.	0.814
LOC115579700	strap	ENSSAUP00010002602	ENSSAUP00010021575	Mothers against decapentaplegic homolog 6-like.	Serine/threonine kinase receptor associated protein.	0.778
LOC115583431	LOC115579700	ENSSAUP00010016624	ENSSAUP00010002602	Protein TMEPAI-like.	Mothers against decapentaplegic homolog 6-like.	0.481
LOC115583431	smad6	ENSSAUP00010016624	ENSSAUP00010026796	Protein TMEPAI-like.	SMAD family member 6.	0.481
LOC115583431	smad7	ENSSAUP00010016624	ENSSAUP00010031842	Protein TMEPAI-like.	SMAD family member 7.	0.481
LOC115583639	LOC115579700	ENSSAUP00010034264	ENSSAUP00010002602	Ski oncogene-like.	Mothers against decapentaplegic homolog 6-like.	0.581
LOC115583639	smad6	ENSSAUP00010034264	ENSSAUP00010026796	Ski oncogene-like.	SMAD family member 6.	0.581
LOC115583639	smad7	ENSSAUP00010034264	ENSSAUP00010031842	Ski oncogene-like.	SMAD family member 7.	0.581
bambi	LOC115579700	ENSSAUP00010063325	ENSSAUP00010002602	BMP and activin membrane bound inhibitor.	Mothers against decapentaplegic homolog 6-like.	0.782