(41 nodes) Negative regulation of BMP signaling pathway network (Sparus aurata)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	skor2	SKI family transcriptional corepressor 2. (805 aa)
	NBL1	NBL1, DAN family BMP antagonist. (204 aa)
	LOC115579753	SKI family transcriptional corepressor 1 homolog-B-like. (794 aa)
	LOC115579700	Mothers against decapentaplegic homolog 6-like. (506 aa)
	lemd3	LEM domain containing 3. (859 aa)
	SMURF2	SMAD specific E3 ubiquitin protein ligase 2. (753 aa)
	LOC115575625	E3 ubiquitin-protein ligase SMURF2. (770 aa)
	LOC115580265	DAN domain family member 5-like. (250 aa)
	vwc2l	Von Willebrand factor C domain containing 2 like. (269 aa)
	LOC115578445	Sclerostin domain-containing protein 1-like. (207 aa)
	fstl3	Follistatin like 3. (317 aa)
	sostdc1	Sclerostin domain containing 1. (217 aa)
	sorl1	Sortilin related receptor 1. (2235 aa)
	ENSSAUP00010022153	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2b. (492 aa)
	LOC115573618	Spartin-like. (598 aa)
	LOC115595254	Secreted frizzled-related protein 2-like. (333 aa)
	smad6	SMAD family member 6. (491 aa)
	skor1	SKI family transcriptional corepressor 1. (747 aa)
	LOC115591259	CTD small phosphatase-like protein 3. (379 aa)
	bmper	BMP binding endothelial regulator. (692 aa)
	smad7	SMAD family member 7. (376 aa)
	LOC115583639	Ski oncogene-like. (695 aa)
	LOC115586236	CTD small phosphatase-like protein 2-A. (474 aa)
	ENSSAUP00010036931	Gremlin 1a, DAN family BMP antagonist. (163 aa)
	ENSSAUP00010038265	Noggin 2. (212 aa)
	smurf1	SMAD specific E3 ubiquitin protein ligase 1. (763 aa)
	ENSSAUP00010042439	Spartin a. (559 aa)
	LOC115596278	Dickkopf-related protein 1-like. (251 aa)
	LOC115575017	Noggin-like. (223 aa)
	GREM1	Gremlin-1-like. (182 aa)
	sfrp2	Secreted frizzled related protein 2. (324 aa)
	ENSSAUP00010051938	annotation not available (476 aa)
	ski	SKI proto-oncogene. (728 aa)
	ENSSAUP00010057930	Chordin. (905 aa)
	ENSSAUP00010058030	Chordin. (941 aa)
	bambi	BMP and activin membrane bound inhibitor. (262 aa)
	LOC115578889	Serine protease HTRA3-like. (489 aa)
	LOC115594469	Chordin-like protein 2. (444 aa)
	ENSSAUP00010067344	Gremlin 2, DAN family BMP antagonist a. (173 aa)
	tnfaip6	TNF alpha induced protein 6. (263 aa)
	skil	SKI like proto-oncogene. (773 aa)

Your Current Organism:

Sparus aurata

NCBI taxonomy Id: 8175
Other names: Aurata aurata, S. aurata, Sparus auratus, gilthead bream, gilthead seabream, silver seabream

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSAUP00010036931	ENSSAUP00010067344	ENSSAUP00010036931	ENSSAUP00010067344	Gremlin 1a, DAN family BMP antagonist.	Gremlin 2, DAN family BMP antagonist a.	0.852
ENSSAUP00010036931	GREM1	ENSSAUP00010036931	ENSSAUP00010045796	Gremlin 1a, DAN family BMP antagonist.	Gremlin-1-like.	0.848
ENSSAUP00010036931	LOC115575017	ENSSAUP00010036931	ENSSAUP00010045494	Gremlin 1a, DAN family BMP antagonist.	Noggin-like.	0.465
ENSSAUP00010038265	ENSSAUP00010057930	ENSSAUP00010038265	ENSSAUP00010057930	Noggin 2.	Chordin.	0.489
ENSSAUP00010038265	ENSSAUP00010058030	ENSSAUP00010038265	ENSSAUP00010058030	Noggin 2.	Chordin.	0.489
ENSSAUP00010038265	LOC115575017	ENSSAUP00010038265	ENSSAUP00010045494	Noggin 2.	Noggin-like.	0.850
ENSSAUP00010042439	LOC115573618	ENSSAUP00010042439	ENSSAUP00010023184	Spartin a.	Spartin-like.	0.849
ENSSAUP00010057930	ENSSAUP00010038265	ENSSAUP00010057930	ENSSAUP00010038265	Chordin.	Noggin 2.	0.489
ENSSAUP00010057930	LOC115575017	ENSSAUP00010057930	ENSSAUP00010045494	Chordin.	Noggin-like.	0.431
ENSSAUP00010057930	bmper	ENSSAUP00010057930	ENSSAUP00010030061	Chordin.	BMP binding endothelial regulator.	0.613
ENSSAUP00010057930	tnfaip6	ENSSAUP00010057930	ENSSAUP00010068470	Chordin.	TNF alpha induced protein 6.	0.536
ENSSAUP00010058030	ENSSAUP00010038265	ENSSAUP00010058030	ENSSAUP00010038265	Chordin.	Noggin 2.	0.489
ENSSAUP00010058030	LOC115575017	ENSSAUP00010058030	ENSSAUP00010045494	Chordin.	Noggin-like.	0.431
ENSSAUP00010058030	bmper	ENSSAUP00010058030	ENSSAUP00010030061	Chordin.	BMP binding endothelial regulator.	0.613
ENSSAUP00010058030	tnfaip6	ENSSAUP00010058030	ENSSAUP00010068470	Chordin.	TNF alpha induced protein 6.	0.536
ENSSAUP00010067344	ENSSAUP00010036931	ENSSAUP00010067344	ENSSAUP00010036931	Gremlin 2, DAN family BMP antagonist a.	Gremlin 1a, DAN family BMP antagonist.	0.852
ENSSAUP00010067344	GREM1	ENSSAUP00010067344	ENSSAUP00010045796	Gremlin 2, DAN family BMP antagonist a.	Gremlin-1-like.	0.850
ENSSAUP00010067344	LOC115580265	ENSSAUP00010067344	ENSSAUP00010007707	Gremlin 2, DAN family BMP antagonist a.	DAN domain family member 5-like.	0.422
GREM1	ENSSAUP00010036931	ENSSAUP00010045796	ENSSAUP00010036931	Gremlin-1-like.	Gremlin 1a, DAN family BMP antagonist.	0.848
GREM1	ENSSAUP00010067344	ENSSAUP00010045796	ENSSAUP00010067344	Gremlin-1-like.	Gremlin 2, DAN family BMP antagonist a.	0.850