(11 nodes) Response to fluid shear stress network (Sparus aurata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSSAUP00010000851	Polycystic kidney disease 1a. (4619 aa)
	LOC115579700	Mothers against decapentaplegic homolog 6-like. (506 aa)
	ubiad1	UbiA prenyltransferase domain containing 1. (349 aa)
	nfe2l2	Nuclear factor, erythroid 2 like 2. (612 aa)
	smad6	SMAD family member 6. (491 aa)
	smad7	SMAD family member 7. (376 aa)
	ptgs2	Prostaglandin-endoperoxide synthase 2. (627 aa)
	pkd2	Polycystin 2, transient receptor potential cation channel. (903 aa)
	p2rx7	Purinergic receptor P2X 7. (576 aa)
	ENSSAUP00010048672	X-box binding protein 1. (264 aa)
	ENSSAUP00010059389	Polycystic kidney disease 1b. (2993 aa)

Your Current Organism:

Sparus aurata

NCBI taxonomy Id: 8175
Other names: Aurata aurata, S. aurata, Sparus auratus, gilthead bream, gilthead seabream, silver seabream

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSAUP00010000851	pkd2	ENSSAUP00010000851	ENSSAUP00010038746	Polycystic kidney disease 1a.	Polycystin 2, transient receptor potential cation channel.	0.907
ENSSAUP00010059389	pkd2	ENSSAUP00010059389	ENSSAUP00010038746	Polycystic kidney disease 1b.	Polycystin 2, transient receptor potential cation channel.	0.907
LOC115579700	smad7	ENSSAUP00010002602	ENSSAUP00010031842	Mothers against decapentaplegic homolog 6-like.	SMAD family member 7.	0.814
pkd2	ENSSAUP00010000851	ENSSAUP00010038746	ENSSAUP00010000851	Polycystin 2, transient receptor potential cation channel.	Polycystic kidney disease 1a.	0.907
pkd2	ENSSAUP00010059389	ENSSAUP00010038746	ENSSAUP00010059389	Polycystin 2, transient receptor potential cation channel.	Polycystic kidney disease 1b.	0.907
smad6	smad7	ENSSAUP00010026796	ENSSAUP00010031842	SMAD family member 6.	SMAD family member 7.	0.814
smad7	LOC115579700	ENSSAUP00010031842	ENSSAUP00010002602	SMAD family member 7.	Mothers against decapentaplegic homolog 6-like.	0.814
smad7	smad6	ENSSAUP00010031842	ENSSAUP00010026796	SMAD family member 7.	SMAD family member 6.	0.814