(18 nodes) I-SMAD binding network (Sparus aurata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC115579700	Mothers against decapentaplegic homolog 6-like. (506 aa)
	AXIN2	Axin-2-like. (793 aa)
	LOC115580406	Mothers against decapentaplegic homolog 3. (449 aa)
	ENSSAUP00010004222	annotation not available (838 aa)
	axin1	Axin 1. (869 aa)
	ENSSAUP00010014730	annotation not available (519 aa)
	smad1	SMAD family member 1. (470 aa)
	smad6	SMAD family member 6. (491 aa)
	smad3	SMAD family member 3. (446 aa)
	smad7	SMAD family member 7. (376 aa)
	smad2	SMAD family member 2. (474 aa)
	LOC115578329	Mothers against decapentaplegic homolog 4-like. (616 aa)
	smad9	SMAD family member 9. (467 aa)
	LOC115575929	Axin-2-like. (841 aa)
	LOC115581835	Mothers against decapentaplegic homolog 2. (467 aa)
	LOC115569095	Mothers against decapentaplegic homolog 5. (475 aa)
	LOC115592497	Mothers against decapentaplegic homolog 4-like. (512 aa)
	ints8	Integrator complex subunit 8. (1026 aa)

Your Current Organism:

Sparus aurata

NCBI taxonomy Id: 8175
Other names: Aurata aurata, S. aurata, Sparus auratus, gilthead bream, gilthead seabream, silver seabream

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	ENSSAUP00010004222	ENSSAUP00010000376	ENSSAUP00010004222	Axin-2-like.	annotation not available	0.834
AXIN2	LOC115575929	ENSSAUP00010000376	ENSSAUP00010045326	Axin-2-like.	Axin-2-like.	0.847
AXIN2	axin1	ENSSAUP00010000376	ENSSAUP00010007105	Axin-2-like.	Axin 1.	0.834
ENSSAUP00010004222	AXIN2	ENSSAUP00010004222	ENSSAUP00010000376	annotation not available	Axin-2-like.	0.834
ENSSAUP00010004222	LOC115575929	ENSSAUP00010004222	ENSSAUP00010045326	annotation not available	Axin-2-like.	0.834
ENSSAUP00010014730	LOC115569095	ENSSAUP00010014730	ENSSAUP00010058180	annotation not available	Mothers against decapentaplegic homolog 5.	0.960
ENSSAUP00010014730	LOC115578329	ENSSAUP00010014730	ENSSAUP00010036504	annotation not available	Mothers against decapentaplegic homolog 4-like.	0.847
ENSSAUP00010014730	LOC115579700	ENSSAUP00010014730	ENSSAUP00010002602	annotation not available	Mothers against decapentaplegic homolog 6-like.	0.638
ENSSAUP00010014730	LOC115580406	ENSSAUP00010014730	ENSSAUP00010002596	annotation not available	Mothers against decapentaplegic homolog 3.	0.942
ENSSAUP00010014730	LOC115581835	ENSSAUP00010014730	ENSSAUP00010052525	annotation not available	Mothers against decapentaplegic homolog 2.	0.942
ENSSAUP00010014730	LOC115592497	ENSSAUP00010014730	ENSSAUP00010059920	annotation not available	Mothers against decapentaplegic homolog 4-like.	0.846
ENSSAUP00010014730	ints8	ENSSAUP00010014730	ENSSAUP00010066337	annotation not available	Integrator complex subunit 8.	0.841
ENSSAUP00010014730	smad1	ENSSAUP00010014730	ENSSAUP00010017598	annotation not available	SMAD family member 1.	0.959
ENSSAUP00010014730	smad2	ENSSAUP00010014730	ENSSAUP00010031921	annotation not available	SMAD family member 2.	0.942
ENSSAUP00010014730	smad3	ENSSAUP00010014730	ENSSAUP00010026975	annotation not available	SMAD family member 3.	0.942
ENSSAUP00010014730	smad6	ENSSAUP00010014730	ENSSAUP00010026796	annotation not available	SMAD family member 6.	0.638
ENSSAUP00010014730	smad7	ENSSAUP00010014730	ENSSAUP00010031842	annotation not available	SMAD family member 7.	0.638
ENSSAUP00010014730	smad9	ENSSAUP00010014730	ENSSAUP00010041387	annotation not available	SMAD family member 9.	0.960
LOC115569095	ENSSAUP00010014730	ENSSAUP00010058180	ENSSAUP00010014730	Mothers against decapentaplegic homolog 5.	annotation not available	0.960
LOC115569095	LOC115578329	ENSSAUP00010058180	ENSSAUP00010036504	Mothers against decapentaplegic homolog 5.	Mothers against decapentaplegic homolog 4-like.	0.952