(9 nodes) Nicotinamide nucleotide biosynthetic process network (Monosiga brevicollis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A9UVU0_MONBE	Predicted protein. (378 aa)
	A9UZ86_MONBE	Predicted protein. (414 aa)
	A9UZQ0_MONBE	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (571 aa)
	KMO	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (438 aa)
	A9V531_MONBE	Nicotinamide-nucleotide adenylyltransferase. (260 aa)
	A9VB31_MONBE	Predicted protein. (574 aa)
	A9UQD2_MONBE	Uncharacterized protein. (297 aa)
	A9UX53_MONBE	Predicted protein. (508 aa)
	kynu	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (460 aa)

Your Current Organism:

Monosiga brevicollis

NCBI taxonomy Id: 81824
Other names: M. brevicollis

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A9UQD2_MONBE	A9UZQ0_MONBE	A9UQD2	A9UZQ0	Uncharacterized protein.	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.415
A9UQD2_MONBE	A9V531_MONBE	A9UQD2	A9V531	Uncharacterized protein.	Nicotinamide-nucleotide adenylyltransferase.	0.438
A9UVU0_MONBE	A9UZQ0_MONBE	A9UVU0	A9UZQ0	Predicted protein.	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.526
A9UVU0_MONBE	KMO	A9UVU0	A9V478	Predicted protein.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.547
A9UVU0_MONBE	kynu	A9UVU0	A9V3C0	Predicted protein.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.954
A9UX53_MONBE	A9V531_MONBE	A9UX53	A9V531	Predicted protein.	Nicotinamide-nucleotide adenylyltransferase.	0.947
A9UZQ0_MONBE	A9UQD2_MONBE	A9UZQ0	A9UQD2	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Uncharacterized protein.	0.415
A9UZQ0_MONBE	A9UVU0_MONBE	A9UZQ0	A9UVU0	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Predicted protein.	0.526
A9UZQ0_MONBE	A9V531_MONBE	A9UZQ0	A9V531	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Nicotinamide-nucleotide adenylyltransferase.	0.983
A9UZQ0_MONBE	A9VB31_MONBE	A9UZQ0	A9VB31	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Predicted protein.	0.415
A9UZQ0_MONBE	KMO	A9UZQ0	A9V478	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.405
A9UZQ0_MONBE	kynu	A9UZQ0	A9V3C0	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.530
A9V531_MONBE	A9UQD2_MONBE	A9V531	A9UQD2	Nicotinamide-nucleotide adenylyltransferase.	Uncharacterized protein.	0.438
A9V531_MONBE	A9UX53_MONBE	A9V531	A9UX53	Nicotinamide-nucleotide adenylyltransferase.	Predicted protein.	0.947
A9V531_MONBE	A9UZQ0_MONBE	A9V531	A9UZQ0	Nicotinamide-nucleotide adenylyltransferase.	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.983
A9V531_MONBE	A9VB31_MONBE	A9V531	A9VB31	Nicotinamide-nucleotide adenylyltransferase.	Predicted protein.	0.941
A9V531_MONBE	KMO	A9V531	A9V478	Nicotinamide-nucleotide adenylyltransferase.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.483
A9V531_MONBE	kynu	A9V531	A9V3C0	Nicotinamide-nucleotide adenylyltransferase.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.453
A9VB31_MONBE	A9UZQ0_MONBE	A9VB31	A9UZQ0	Predicted protein.	Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.	0.415
A9VB31_MONBE	A9V531_MONBE	A9VB31	A9V531	Predicted protein.	Nicotinamide-nucleotide adenylyltransferase.	0.941