(108 nodes) Actin cytoskeleton organization network (Monosiga brevicollis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A9VEE3_MONBE	Predicted protein. (558 aa)
	Mbre_RhoGAP6	RhoGAP domain-containing protein. (895 aa)
	Mbre_LIMK1	Kinase domain-containing protein. (567 aa)
	A9UNS9_MONBE	Uncharacterized protein. (1061 aa)
	A9UNT2_MONBE	I/LWEQ domain-containing protein. (177 aa)
	A9UPI6_MONBE	Uncharacterized protein. (477 aa)
	A9UPX5_MONBE	Uncharacterized protein; Belongs to the protein kinase superfamily. (327 aa)
	A9UQ75_MONBE	Uncharacterized protein. (2144 aa)
	A9UQM4_MONBE	LIM zinc-binding domain-containing protein. (77 aa)
	A9UR23_MONBE	Predicted protein. (228 aa)
	A9UR27_MONBE	Predicted protein. (2580 aa)
	A9UR80_MONBE	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (374 aa)
	A9URA4_MONBE	Predicted protein. (1593 aa)
	A9URB1_MONBE	Predicted protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1025 aa)
	A9URK8_MONBE	Coronin; Belongs to the WD repeat coronin family. (461 aa)
	A9URR1_MONBE	Predicted protein. (363 aa)
	A9URT4_MONBE	Predicted protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1224 aa)
	A9US63_MONBE	Predicted protein. (217 aa)
	A9USD4_MONBE	Predicted protein. (1411 aa)
	A9USD5_MONBE	Predicted protein. (149 aa)
	A9USK9_MONBE	Predicted protein; Belongs to the small GTPase superfamily. Arf family. (176 aa)
	A9USM9_MONBE	Predicted protein. (623 aa)
	A9UST0_MONBE	Predicted protein. (3767 aa)
	A9UST9_MONBE	Predicted protein. (2423 aa)
	A9USX8_MONBE	Predicted protein. (237 aa)
	A9UTC5_MONBE	Predicted protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1741 aa)
	A9UTE0_MONBE	Predicted protein. (1127 aa)
	A9UTF4_MONBE	Predicted protein. (268 aa)
	A9UTZ5_MONBE	Predicted protein. (221 aa)
	A9UU42_MONBE	Predicted protein. (1419 aa)
	A9UU44_MONBE	Predicted protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (771 aa)
	A9UUA5_MONBE	Predicted protein. (881 aa)
	A9UUB1_MONBE	Predicted protein. (344 aa)
	A9UVG5_MONBE	Predicted protein. (1181 aa)
	A9UVN8_MONBE	Predicted protein. (773 aa)
	A9UW41_MONBE	Predicted protein. (86 aa)
	A9UWI5_MONBE	Predicted protein. (194 aa)
	A9UWI6_MONBE	Predicted protein. (193 aa)
	A9UWK8_MONBE	Predicted protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1054 aa)
	A9UWS2_MONBE	Predicted protein. (973 aa)
	A9UWT8_MONBE	Predicted protein. (80 aa)
	A9UWY0_MONBE	Predicted protein. (414 aa)
	A9UXF2_MONBE	Predicted protein. (1390 aa)
	A9UXP7_MONBE	Predicted protein. (189 aa)
	A9UXV2_MONBE	Predicted protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1158 aa)
	A9UYD8_MONBE	Predicted protein. (796 aa)
	A9UYG1_MONBE	Predicted protein. (1640 aa)
	A9UZC5_MONBE	Predicted protein. (836 aa)
	A9V000_MONBE	Predicted protein. (744 aa)
	A9V004_MONBE	Predicted protein. (857 aa)
	A9V006_MONBE	Predicted protein; Belongs to the actin family. (409 aa)
	A9V031_MONBE	Predicted protein. (143 aa)
	A9V0Y2_MONBE	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (182 aa)
	A9V0Y7_MONBE	Adenylyl cyclase-associated protein; Belongs to the CAP family. (775 aa)
	A9V176_MONBE	Predicted protein. (1586 aa)
	A9V1C6_MONBE	Predicted protein. (566 aa)
	A9V1E2_MONBE	Predicted protein. (339 aa)
	A9V1E3_MONBE	Predicted protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (415 aa)
	A9V1E4_MONBE	Predicted protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (138 aa)
	A9V1N4_MONBE	Predicted protein. (1236 aa)
	A9V1P2_MONBE	Predicted protein. (882 aa)
	A9V1R1_MONBE	Predicted protein; Belongs to the actin-binding proteins ADF family. (140 aa)
	A9V1R7_MONBE	Predicted protein. (1099 aa)
	A9V263_MONBE	Predicted protein. (421 aa)
	A9V2A9_MONBE	Predicted protein. (1472 aa)
	A9V2D9_MONBE	Predicted protein. (344 aa)
	A9V2E0_MONBE	Predicted protein. (910 aa)
	A9V2F3_MONBE	Predicted protein. (413 aa)
	A9V2P4_MONBE	Predicted protein. (815 aa)
	A9V3K1_MONBE	Predicted protein. (289 aa)
	A9V3S7_MONBE	Predicted protein. (282 aa)
	A9V419_MONBE	Predicted protein. (305 aa)
	A9V487_MONBE	Fascin. (499 aa)
	A9V4E1_MONBE	Predicted protein. (1371 aa)
	A9V547_MONBE	Predicted protein. (599 aa)
	A9V585_MONBE	Predicted protein. (191 aa)
	A9V5G7_MONBE	Predicted protein. (1137 aa)
	A9V5J9_MONBE	Predicted protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (850 aa)
	A9V5T2_MONBE	Predicted protein. (1321 aa)
	A9V6Q7_MONBE	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (274 aa)
	A9V6R1_MONBE	Predicted protein. (531 aa)
	A9V6V2_MONBE	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (398 aa)
	A9V6X3_MONBE	Predicted protein. (1269 aa)
	A9V6X6_MONBE	Predicted protein. (244 aa)
	A9V703_MONBE	Predicted protein. (2473 aa)
	A9V713_MONBE	Predicted protein. (1293 aa)
	A9V7P7_MONBE	Predicted protein. (6448 aa)
	A9V854_MONBE	Predicted protein. (508 aa)
	A9V866_MONBE	Predicted protein. (135 aa)
	A9V8B5_MONBE	Predicted protein. (427 aa)
	A9V8I0_MONBE	Predicted protein. (1781 aa)
	A9V8S1_MONBE	Predicted protein. (342 aa)
	A9V8W0_MONBE	Predicted protein. (906 aa)
	A9V9I1_MONBE	Predicted protein. (304 aa)
	A9V9W5_MONBE	Predicted protein. (492 aa)
	A9VAA1_MONBE	Predicted protein. (1610 aa)
	A9VAA9_MONBE	Predicted protein. (1509 aa)
	A9VAE7_MONBE	Predicted protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1076 aa)
	A9VAW6_MONBE	Predicted protein. (889 aa)
	A9VAY4_MONBE	Predicted protein. (833 aa)
	A9VAZ3_MONBE	Predicted protein. (1037 aa)
	A9VBK0_MONBE	Predicted protein. (564 aa)
	A9VC33_MONBE	Predicted protein. (1203 aa)
	A9VC36_MONBE	Predicted protein. (1075 aa)
	A9VC70_MONBE	Predicted protein. (192 aa)
	A9VCB7_MONBE	Predicted protein. (1233 aa)
	A9VD21_MONBE	Fascin. (489 aa)
	A9VDA5_MONBE	Predicted protein. (1156 aa)

Your Current Organism:

Monosiga brevicollis

NCBI taxonomy Id: 81824
Other names: M. brevicollis

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A9UNT2_MONBE	A9USM9_MONBE	A9UNT2	A9USM9	I/LWEQ domain-containing protein.	Predicted protein.	0.426
A9UNT2_MONBE	A9V2D9_MONBE	A9UNT2	A9V2D9	I/LWEQ domain-containing protein.	Predicted protein.	0.564
A9UNT2_MONBE	A9V6R1_MONBE	A9UNT2	A9V6R1	I/LWEQ domain-containing protein.	Predicted protein.	0.437
A9UNT2_MONBE	A9V6V2_MONBE	A9UNT2	A9V6V2	I/LWEQ domain-containing protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.454
A9UNT2_MONBE	A9V866_MONBE	A9UNT2	A9V866	I/LWEQ domain-containing protein.	Predicted protein.	0.564
A9UNT2_MONBE	A9VAA1_MONBE	A9UNT2	A9VAA1	I/LWEQ domain-containing protein.	Predicted protein.	0.437
A9UPI6_MONBE	A9USX8_MONBE	A9UPI6	A9USX8	Uncharacterized protein.	Predicted protein.	0.615
A9UPI6_MONBE	A9UVG5_MONBE	A9UPI6	A9UVG5	Uncharacterized protein.	Predicted protein.	0.411
A9UPI6_MONBE	A9UWI5_MONBE	A9UPI6	A9UWI5	Uncharacterized protein.	Predicted protein.	0.615
A9UPI6_MONBE	A9UWI6_MONBE	A9UPI6	A9UWI6	Uncharacterized protein.	Predicted protein.	0.615
A9UPI6_MONBE	A9UXP7_MONBE	A9UPI6	A9UXP7	Uncharacterized protein.	Predicted protein.	0.513
A9UPI6_MONBE	A9UZC5_MONBE	A9UPI6	A9UZC5	Uncharacterized protein.	Predicted protein.	0.411
A9UPI6_MONBE	A9V1N4_MONBE	A9UPI6	A9V1N4	Uncharacterized protein.	Predicted protein.	0.447
A9UPI6_MONBE	A9V585_MONBE	A9UPI6	A9V585	Uncharacterized protein.	Predicted protein.	0.532
A9UPI6_MONBE	A9VAZ3_MONBE	A9UPI6	A9VAZ3	Uncharacterized protein.	Predicted protein.	0.491
A9UPI6_MONBE	A9VC70_MONBE	A9UPI6	A9VC70	Uncharacterized protein.	Predicted protein.	0.532
A9UPX5_MONBE	A9USX8_MONBE	A9UPX5	A9USX8	Uncharacterized protein; Belongs to the protein kinase superfamily.	Predicted protein.	0.615
A9UPX5_MONBE	A9UVG5_MONBE	A9UPX5	A9UVG5	Uncharacterized protein; Belongs to the protein kinase superfamily.	Predicted protein.	0.411
A9UPX5_MONBE	A9UWI5_MONBE	A9UPX5	A9UWI5	Uncharacterized protein; Belongs to the protein kinase superfamily.	Predicted protein.	0.615
A9UPX5_MONBE	A9UWI6_MONBE	A9UPX5	A9UWI6	Uncharacterized protein; Belongs to the protein kinase superfamily.	Predicted protein.	0.615