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A9VDW9_MONBE A9VDW9_MONBE A9VE06_MONBE A9VE06_MONBE A9VE47_MONBE A9VE47_MONBE ITPA_MONBE ITPA_MONBE TUB_1 TUB_1 TUA TUA KATNA1 KATNA1 A9V8R9_MONBE A9V8R9_MONBE A9V907_MONBE A9V907_MONBE A9V999_MONBE A9V999_MONBE A9VA31_MONBE A9VA31_MONBE A9VA79_MONBE A9VA79_MONBE A9VAJ0_MONBE A9VAJ0_MONBE A9VAS0_MONBE A9VAS0_MONBE A9VB34_MONBE A9VB34_MONBE A9VB45_MONBE A9VB45_MONBE A9VB93_MONBE A9VB93_MONBE A9VBA3_MONBE A9VBA3_MONBE A9UNW6_MONBE A9UNW6_MONBE RSSA_MONBE RSSA_MONBE A9UPJ4_MONBE A9UPJ4_MONBE A9UPW0_MONBE A9UPW0_MONBE A9UQ56_MONBE A9UQ56_MONBE MTNA_MONBE MTNA_MONBE A9UQF5_MONBE A9UQF5_MONBE A9UQF8_MONBE A9UQF8_MONBE A9UQJ9_MONBE A9UQJ9_MONBE EIF3E_MONBE EIF3E_MONBE A9UQY4_MONBE A9UQY4_MONBE A9UR66_MONBE A9UR66_MONBE A9UR80_MONBE A9UR80_MONBE A9VBM3_MONBE A9VBM3_MONBE A9VBS7_MONBE A9VBS7_MONBE A9VC19_MONBE A9VC19_MONBE MTND_MONBE MTND_MONBE MTNB_MONBE MTNB_MONBE A9VCR0_MONBE A9VCR0_MONBE A9VCY3_MONBE A9VCY3_MONBE EIF3L_MONBE EIF3L_MONBE A9V7Y8_MONBE A9V7Y8_MONBE A9VD21_MONBE A9VD21_MONBE A9URD2_MONBE A9URD2_MONBE A9URL9_MONBE A9URL9_MONBE A9URN8_MONBE A9URN8_MONBE A9URT6_MONBE A9URT6_MONBE A9US53_MONBE A9US53_MONBE A9US86_MONBE A9US86_MONBE A9US91_MONBE A9US91_MONBE A9USG4_MONBE A9USG4_MONBE RS3A_MONBE RS3A_MONBE A9USL5_MONBE A9USL5_MONBE A9UST4_MONBE A9UST4_MONBE A9USY8_MONBE A9USY8_MONBE A9UT33_MONBE A9UT33_MONBE PURA_MONBE PURA_MONBE TUB_2 TUB_2 A9UTV6_MONBE A9UTV6_MONBE A9UU61_MONBE A9UU61_MONBE A9UU74_MONBE A9UU74_MONBE A9UU80_MONBE A9UU80_MONBE A9UU85_MONBE A9UU85_MONBE EIF6 EIF6 A9UUD7_MONBE A9UUD7_MONBE A9UV63_MONBE A9UV63_MONBE A9UV90_MONBE A9UV90_MONBE LSM1 LSM1 A9UVR8_MONBE A9UVR8_MONBE A9UW43_MONBE A9UW43_MONBE A9UW93_MONBE A9UW93_MONBE A9UWC1_MONBE A9UWC1_MONBE A9UWK9_MONBE A9UWK9_MONBE A9UWM7_MONBE A9UWM7_MONBE A9UWV7_MONBE A9UWV7_MONBE A9UX30_MONBE A9UX30_MONBE A9UX42_MONBE A9UX42_MONBE A9UXF4_MONBE A9UXF4_MONBE A9UXH7_MONBE A9UXH7_MONBE A9UXM0_MONBE A9UXM0_MONBE A9UYD3_MONBE A9UYD3_MONBE A9UYE2_MONBE A9UYE2_MONBE A9UYP4_MONBE A9UYP4_MONBE A9UZ46_MONBE A9UZ46_MONBE A9UZC1_MONBE A9UZC1_MONBE A9UZQ6_MONBE A9UZQ6_MONBE A9V001_MONBE A9V001_MONBE A9V0P3_MONBE A9V0P3_MONBE A9V0Y2_MONBE A9V0Y2_MONBE A9V1I7_MONBE A9V1I7_MONBE A9V1N3_MONBE A9V1N3_MONBE A9V1V8_MONBE A9V1V8_MONBE A9V222_MONBE A9V222_MONBE ENOPH_MONBE ENOPH_MONBE kynu kynu A9V3N2_MONBE A9V3N2_MONBE EIF3H_MONBE EIF3H_MONBE A9V3Q3_MONBE A9V3Q3_MONBE A9V3X7_MONBE A9V3X7_MONBE A9V487_MONBE A9V487_MONBE A9V489_MONBE A9V489_MONBE A9V4A9_MONBE A9V4A9_MONBE A9V4C0_MONBE A9V4C0_MONBE A9V4G5_MONBE A9V4G5_MONBE A9V4M8_MONBE A9V4M8_MONBE EIF3A_MONBE EIF3A_MONBE A9V581_MONBE A9V581_MONBE A9V629_MONBE A9V629_MONBE A9V684_MONBE A9V684_MONBE A9V6L5_MONBE A9V6L5_MONBE A9V6Q7_MONBE A9V6Q7_MONBE A9V6V2_MONBE A9V6V2_MONBE A9V701_MONBE A9V701_MONBE KATNAL2 KATNAL2 DRE2_MONBE DRE2_MONBE LIS1_MONBE LIS1_MONBE NUBP2_MONBE NUBP2_MONBE A9V7K9_MONBE A9V7K9_MONBE
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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co-expression
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A9VDW9_MONBECoatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (945 aa)
A9VE06_MONBEPredicted protein. (534 aa)
A9VE47_MONBEEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (319 aa)
ITPA_MONBEInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (199 aa)
TUB_1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
TUATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. (494 aa)
A9V8R9_MONBED-aminoacyl-tRNA deacylase. (900 aa)
A9V907_MONBET-complex protein 1 subunit delta. (527 aa)
A9V999_MONBEPredicted protein. (391 aa)
A9VA31_MONBEProteasome subunit beta; Belongs to the peptidase T1B family. (224 aa)
A9VA79_MONBEUMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (201 aa)
A9VAJ0_MONBEProteasome subunit alpha type. (254 aa)
A9VAS0_MONBEDipeptidyl peptidase 3; Belongs to the peptidase M49 family. (742 aa)
A9VB34_MONBEInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (530 aa)
A9VB45_MONBET-complex protein 1 subunit gamma. (555 aa)
A9VB93_MONBEProteasome subunit alpha type. (246 aa)
A9VBA3_MONBEGPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. (332 aa)
A9UNW6_MONBEPCI domain-containing protein. (586 aa)
RSSA_MONBE40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. (278 aa)
A9UPJ4_MONBERibosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (216 aa)
A9UPW0_MONBEPUA domain-containing protein. (185 aa)
A9UQ56_MONBET-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (559 aa)
MTNA_MONBEMethylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (361 aa)
A9UQF5_MONBECoatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (860 aa)
A9UQF8_MONBERibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (310 aa)
A9UQJ9_MONBEProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (392 aa)
EIF3E_MONBEEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (485 aa)
A9UQY4_MONBESignal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (620 aa)
A9UR66_MONBEEukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs. (544 aa)
A9UR80_MONBEActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (374 aa)
A9VBM3_MONBEEukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (1893 aa)
A9VBS7_MONBE60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (521 aa)
A9VC19_MONBEPredicted protein. (1210 aa)
MTND_MONBE1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (176 aa)
MTNB_MONBEProbable methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (249 aa)
A9VCR0_MONBESignal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (597 aa)
A9VCY3_MONBEPredicted protein. (540 aa)
EIF3L_MONBEEukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (512 aa)
A9V7Y8_MONBEProteasome endopeptidase complex; Belongs to the peptidase T1A family. (624 aa)
A9VD21_MONBEFascin. (489 aa)
A9URD2_MONBEAlanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (1000 aa)
A9URL9_MONBEProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (772 aa)
A9URN8_MONBES-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (233 aa)
A9URT6_MONBEProteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (193 aa)
A9US53_MONBEKatanin p80 WD40 repeat-containing subunit B1 homolog; May participate in a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays; Belongs to the WD repeat KATNB1 family. (578 aa)
A9US86_MONBECoatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1218 aa)
A9US91_MONBECytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. (706 aa)
A9USG4_MONBEProbable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. (341 aa)
RS3A_MONBE40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family. (259 aa)
A9USL5_MONBEATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1085 aa)
A9UST4_MONBEMolybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. (160 aa)
A9USY8_MONBES-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (286 aa)
A9UT33_MONBENADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of the anamorsin/DRE2 homolog. Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family. In the N-terminal section; belongs to the flavodoxin family. (602 aa)
PURA_MONBEAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. (431 aa)
TUB_2Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
A9UTV6_MONBEDynein light chain roadblock. (97 aa)
A9UU61_MONBEDynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (653 aa)
A9UU74_MONBEPhosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions. (257 aa)
A9UU80_MONBEPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (563 aa)
A9UU85_MONBEProteasome subunit alpha type. (256 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (245 aa)
A9UUD7_MONBEEukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (281 aa)
A9UV63_MONBEtRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family. (483 aa)
A9UV90_MONBECytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. (361 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs. (126 aa)
A9UVR8_MONBEAdenylyltransferase and sulfurtransferase MOCS3 homolog; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards U [...] (385 aa)
A9UW43_MONBEEukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (225 aa)
A9UW93_MONBEEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (315 aa)
A9UWC1_MONBEPredicted protein. (438 aa)
A9UWK9_MONBEPredicted protein. (296 aa)
A9UWM7_MONBEProteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (216 aa)
A9UWV7_MONBEDynein light chain. (89 aa)
A9UX30_MONBECysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (392 aa)
A9UX42_MONBEDynein light chain. (104 aa)
A9UXF4_MONBEObg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (394 aa)
A9UXH7_MONBEProteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (247 aa)
A9UXM0_MONBECoatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (295 aa)
A9UYD3_MONBEProteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (211 aa)
A9UYE2_MONBEExportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (945 aa)
A9UYP4_MONBECoatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (530 aa)
A9UZ46_MONBEArp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (297 aa)
A9UZC1_MONBES-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (289 aa)
A9UZQ6_MONBEMethionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). (445 aa)
A9V001_MONBEPredicted protein. (547 aa)
A9V0P3_MONBESpindle pole body component. (754 aa)
A9V0Y2_MONBEActin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (182 aa)
A9V1I7_MONBEUbiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...] (153 aa)
A9V1N3_MONBE3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family. In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family. (1520 aa)
A9V1V8_MONBEInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1062 aa)
A9V222_MONBEProteasome subunit alpha type. (263 aa)
ENOPH_MONBEEnolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (301 aa)
kynuKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (460 aa)
A9V3N2_MONBEPredicted protein. (530 aa)
EIF3H_MONBEEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (354 aa)
A9V3Q3_MONBEPutative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. (302 aa)
A9V3X7_MONBESpindle pole body component. (749 aa)
A9V487_MONBEFascin. (499 aa)
A9V489_MONBEPredicted protein. (375 aa)
A9V4A9_MONBECysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (355 aa)
A9V4C0_MONBEPredicted protein. (556 aa)
A9V4G5_MONBEProteasome subunit alpha type. (248 aa)
A9V4M8_MONBETubulin-specific chaperone A; Belongs to the TBCA family. (115 aa)
EIF3A_MONBEEukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (1052 aa)
A9V581_MONBEPredicted protein. (345 aa)
A9V629_MONBEObg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (394 aa)
A9V684_MONBEProteasome subunit alpha type. (236 aa)
A9V6L5_MONBEEukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (650 aa)
A9V6Q7_MONBEF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (274 aa)
A9V6V2_MONBEActin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (398 aa)
A9V701_MONBESerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (369 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (603 aa)
DRE2_MONBEAnamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...] (282 aa)
LIS1_MONBELissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes. (410 aa)
NUBP2_MONBECytosolic Fe-S cluster assembly factor NUBP2 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (284 aa)
A9V7K9_MONBECoatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (945 aa)
Your Current Organism:
Monosiga brevicollis
NCBI taxonomy Id: 81824
Other names: M. brevicollis
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