(9 nodes) Purine catabolism network (Monosiga brevicollis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	A9UW63_MONBE	Predicted protein; Belongs to the Nudix hydrolase family. (191 aa)
	A9UX49_MONBE	Predicted protein. (144 aa)
	A9URE9_MONBE	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (311 aa)
	ITPA_MONBE	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (199 aa)
	A9VCS7_MONBE	Predicted protein; Belongs to the 5'-nucleotidase family. (546 aa)
	A9V8K8_MONBE	Predicted protein. (552 aa)
	A9V4L5_MONBE	Predicted protein. (555 aa)
	A9V354_MONBE	Predicted protein. (484 aa)
	A9UXL1_MONBE	Predicted protein. (163 aa)

Your Current Organism:

Monosiga brevicollis

NCBI taxonomy Id: 81824
Other names: M. brevicollis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A9URE9_MONBE	A9V4L5_MONBE	A9URE9	A9V4L5	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	Predicted protein.	0.937
A9URE9_MONBE	A9V8K8_MONBE	A9URE9	A9V8K8	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	Predicted protein.	0.632
A9URE9_MONBE	A9VCS7_MONBE	A9URE9	A9VCS7	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	Predicted protein; Belongs to the 5'-nucleotidase family.	0.961
A9UW63_MONBE	A9UX49_MONBE	A9UW63	A9UX49	Predicted protein; Belongs to the Nudix hydrolase family.	Predicted protein.	0.497
A9UW63_MONBE	A9UXL1_MONBE	A9UW63	A9UXL1	Predicted protein; Belongs to the Nudix hydrolase family.	Predicted protein.	0.501
A9UX49_MONBE	A9UW63_MONBE	A9UX49	A9UW63	Predicted protein.	Predicted protein; Belongs to the Nudix hydrolase family.	0.497
A9UX49_MONBE	A9UXL1_MONBE	A9UX49	A9UXL1	Predicted protein.	Predicted protein.	0.670
A9UX49_MONBE	A9V8K8_MONBE	A9UX49	A9V8K8	Predicted protein.	Predicted protein.	0.593
A9UX49_MONBE	A9VCS7_MONBE	A9UX49	A9VCS7	Predicted protein.	Predicted protein; Belongs to the 5'-nucleotidase family.	0.593
A9UX49_MONBE	ITPA_MONBE	A9UX49	A9VE54	Predicted protein.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.515
A9UXL1_MONBE	A9UW63_MONBE	A9UXL1	A9UW63	Predicted protein.	Predicted protein; Belongs to the Nudix hydrolase family.	0.501
A9UXL1_MONBE	A9UX49_MONBE	A9UXL1	A9UX49	Predicted protein.	Predicted protein.	0.670
A9V354_MONBE	A9V4L5_MONBE	A9V354	A9V4L5	Predicted protein.	Predicted protein.	0.438
A9V4L5_MONBE	A9URE9_MONBE	A9V4L5	A9URE9	Predicted protein.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.937
A9V4L5_MONBE	A9V354_MONBE	A9V4L5	A9V354	Predicted protein.	Predicted protein.	0.438
A9V4L5_MONBE	A9VCS7_MONBE	A9V4L5	A9VCS7	Predicted protein.	Predicted protein; Belongs to the 5'-nucleotidase family.	0.909
A9V4L5_MONBE	ITPA_MONBE	A9V4L5	A9VE54	Predicted protein.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.901
A9V8K8_MONBE	A9URE9_MONBE	A9V8K8	A9URE9	Predicted protein.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.632
A9V8K8_MONBE	A9UX49_MONBE	A9V8K8	A9UX49	Predicted protein.	Predicted protein.	0.593
A9VCS7_MONBE	A9URE9_MONBE	A9VCS7	A9URE9	Predicted protein; Belongs to the 5'-nucleotidase family.	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.	0.961